5ICV
Crystal structure of human NatF (hNaa60) bound to a bisubstrate analogue
Summary for 5ICV
Entry DOI | 10.2210/pdb5icv/pdb |
Descriptor | N-alpha-acetyltransferase 60, MET-LYS-ALA-VAL-LIG, [5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)furan-2-yl]methyl (3R)-4-{[3-({(E)-2-[(2,2-dihydroxyethyl)sulfanyl]ethenyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate, ... (4 entities in total) |
Functional Keywords | transferase, acetylation, gnat, nat |
Biological source | Homo sapiens (Human) More |
Cellular location | Golgi apparatus membrane : Q9H7X0 |
Total number of polymer chains | 4 |
Total formula weight | 43618.96 |
Authors | Stove, S.I.,Magin, R.S.,Marmorstein, R.,Arnesen, T. (deposition date: 2016-02-23, release date: 2016-06-22, Last modification date: 2024-01-10) |
Primary citation | Stve, S.I.,Magin, R.S.,Foyn, H.,Haug, B.E.,Marmorstein, R.,Arnesen, T. Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation. Structure, 24:1044-1056, 2016 Cited by PubMed: 27320834DOI: 10.1016/j.str.2016.04.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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