1IHB
CRYSTAL STRUCTURE OF P18-INK4C(INK6)
Summary for 1IHB
| Entry DOI | 10.2210/pdb1ihb/pdb |
| Descriptor | CYCLIN-DEPENDENT KINASE 6 INHIBITOR (2 entities in total) |
| Functional Keywords | cell cycle inhibitor, p18-ink4c(ink6), ankyrin repeat, cdk 4/6 inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 35129.47 |
| Authors | Ravichandran, V.,Swaminathan, K.,Marmorstein, R. (deposition date: 1997-10-25, release date: 1998-12-02, Last modification date: 2024-02-07) |
| Primary citation | Venkataramani, R.,Swaminathan, K.,Marmorstein, R. Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations. Nat.Struct.Biol., 5:74-81, 1998 Cited by PubMed: 9437433DOI: 10.1038/nsb0198-74 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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