5HR5
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![BU of 5hr5 by Molmil](/molmil-images/mine/5hr5) | Bovine Heart 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFKFB2) | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2, ... | 著者 | Crochet, R.B. | 登録日 | 2016-01-22 | 公開日 | 2016-11-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal structure of heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) and the inhibitory influence of citrate on substrate binding. Proteins, 85, 2017
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5HTK
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![BU of 5htk by Molmil](/molmil-images/mine/5htk) | Human Heart 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFKFB2) | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-O-phosphono-beta-D-fructofuranose, ... | 著者 | Crochet, R.B. | 登録日 | 2016-01-27 | 公開日 | 2016-11-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Crystal structure of heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) and the inhibitory influence of citrate on substrate binding. Proteins, 85, 2017
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8K5C
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8K5D
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8K5B
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8HNP
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![BU of 8hnp by Molmil](/molmil-images/mine/8hnp) | Archaeal transcription factor Mutant | 分子名称: | Archaeal transcription regulator | 著者 | Bae, D.W, Cha, S.S. | 登録日 | 2022-12-08 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | 主引用文献 | An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1. Nucleic Acids Res., 51, 2023
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8HNO
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![BU of 8hno by Molmil](/molmil-images/mine/8hno) | Archaeal transcription factor Wild type | 分子名称: | Archaeal transcription regulator | 著者 | Bae, D.W, Cha, S.S. | 登録日 | 2022-12-08 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1. Nucleic Acids Res., 51, 2023
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2RSY
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![BU of 2rsy by Molmil](/molmil-images/mine/2rsy) | Solution structure of the SH2 domain of Csk in complex with a phosphopeptide from Cbp | 分子名称: | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Tyrosine-protein kinase CSK | 著者 | Tanaka, H, Akagi, K, Oneyama, C, Tanaka, M, Sasaki, Y, Kanou, T, Lee, Y, Yokogawa, D, Debenecker, M, Nakagawa, A, Okada, M, Ikegami, T. | 登録日 | 2012-09-10 | 公開日 | 2013-04-10 | 最終更新日 | 2019-12-25 | 実験手法 | SOLUTION NMR | 主引用文献 | Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains. J.Biol.Chem., 288, 2013
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7EWH
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![BU of 7ewh by Molmil](/molmil-images/mine/7ewh) | Crystal structure of human PHGDH in complex with Homoharringtonine | 分子名称: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, D-3-phosphoglycerate dehydrogenase | 著者 | Hsieh, C.H, Cheng, Y.S, Lee, Y.S, Huang, H.C, Juan, H.F. | 登録日 | 2021-05-25 | 公開日 | 2022-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Homoharringtonine as a PHGDH inhibitor: Unraveling metabolic dependencies and developing a potent therapeutic strategy for high-risk neuroblastoma. Biomed Pharmacother, 166, 2023
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7YU1
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7YU0
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8H2G
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8I7W
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![BU of 8i7w by Molmil](/molmil-images/mine/8i7w) | Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer | 分子名称: | 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Park, J.H, Ishimoto, N, Park, S.Y. | 登録日 | 2023-02-02 | 公開日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2. Nat Commun, 14, 2023
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8I7V
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![BU of 8i7v by Molmil](/molmil-images/mine/8i7v) | Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer | 分子名称: | 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Park, J.H, Ishimoto, N, Park, S.Y. | 登録日 | 2023-02-02 | 公開日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2. Nat Commun, 14, 2023
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7YU2
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4F9F
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![BU of 4f9f by Molmil](/molmil-images/mine/4f9f) | Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP and Trehalose | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, VldE, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | 著者 | Cavalier, M.C, Yim, Y.-S, Asamizu, S, Neau, D, Almabruk, K.H, Mahmud, T, Lee, Y.-H. | 登録日 | 2012-05-18 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.807 Å) | 主引用文献 | Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex. Plos One, 7, 2012
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4F97
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![BU of 4f97 by Molmil](/molmil-images/mine/4f97) | Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP and validoxylamine A 7'-phosphate | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Cavalier, M.C, Yim, Y.-S, Asamizu, S, Neau, D, Almabruk, K.H, Mahmud, T, Lee, Y.-H. | 登録日 | 2012-05-18 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.108 Å) | 主引用文献 | Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex. Plos One, 7, 2012
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4F96
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![BU of 4f96 by Molmil](/molmil-images/mine/4f96) | Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, VldE | 著者 | Cavalier, M.C, Yim, Y.-S, Asamizu, S, Neau, D, Almabruk, K.H, Mahmud, T, Lee, Y.-H. | 登録日 | 2012-05-18 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | 主引用文献 | Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex. Plos One, 7, 2012
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4MA4
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![BU of 4ma4 by Molmil](/molmil-images/mine/4ma4) | S-glutathionylated PFKFB3 | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, ACETIC ACID, ... | 著者 | Lee, Y.-H, Seo, M.-S. | 登録日 | 2013-08-15 | 公開日 | 2013-12-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | PFKFB3 Regulates Oxidative Stress Homeostasis via Its S-Glutathionylation in Cancer. J.Mol.Biol., 426, 2014
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7EPP
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2BIF
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![BU of 2bif by Molmil](/molmil-images/mine/2bif) | 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE H256A MUTANT WITH F6P IN PHOSPHATASE ACTIVE SITE | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Yuen, M.H, Hasemann, C.A. | 登録日 | 1998-10-26 | 公開日 | 1999-02-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities. J.Biol.Chem., 274, 1999
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5AUI
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![BU of 5aui by Molmil](/molmil-images/mine/5aui) | |
5AUK
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![BU of 5auk by Molmil](/molmil-images/mine/5auk) | Crystal structure of the Ga-substituted Ferredoxin | 分子名称: | BENZAMIDINE, Ferredoxin-1, SULFATE ION, ... | 著者 | Kurisu, G, Muraki, N, Taya, M, Hase, T. | 登録日 | 2015-04-24 | 公開日 | 2015-09-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | X-ray Structure and Nuclear Magnetic Resonance Analysis of the Interaction Sites of the Ga-Substituted Cyanobacterial Ferredoxin Biochemistry, 54, 2015
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2DW5
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![BU of 2dw5 by Molmil](/molmil-images/mine/2dw5) | Crystal structure of human peptidylarginine deiminase 4 in complex with N-alpha-benzoyl-N5-(2-fluoro-1-iminoethyl)-L-ornithine amide | 分子名称: | CALCIUM ION, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, Protein-arginine deiminase type-4, ... | 著者 | Luo, Y, Arita, K, Sato, M, Thompson, P.R. | 登録日 | 2006-08-04 | 公開日 | 2006-10-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization Biochemistry, 45, 2006
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4OOZ
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![BU of 4ooz by Molmil](/molmil-images/mine/4ooz) | Crystal structure of beta-1,4-D-mannanase from Cryptopygus antarcticus in complex with mannopentaose | 分子名称: | Beta-1,4-mannanase, beta-D-mannopyranose, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose, ... | 著者 | Kim, M.-K, An, Y.J, Jeong, C.-S, Cha, S.-S. | 登録日 | 2014-02-04 | 公開日 | 2014-08-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-based investigation into the functional roles of the extended loop and substrate-recognition sites in an endo-beta-1,4-d-mannanase from the Antarctic springtail, Cryptopygus antarcticus. Proteins, 82, 2014
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