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4MA4

S-glutathionylated PFKFB3

Summary for 4MA4
Entry DOI10.2210/pdb4ma4/pdb
Related2axn 3QPW
Descriptor6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, ADENOSINE-5'-DIPHOSPHATE, MALONIC ACID, ... (7 entities in total)
Functional Keywordss-glutathionylated protein, rossmann fold, phosphoryl transferase, s-glutathionylation, cytosol, hydrolase, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight60956.97
Authors
Lee, Y.-H.,Seo, M.-S. (deposition date: 2013-08-15, release date: 2013-12-11, Last modification date: 2020-07-29)
Primary citationSeo, M.,Lee, Y.H.
PFKFB3 Regulates Oxidative Stress Homeostasis via Its S-Glutathionylation in Cancer.
J.Mol.Biol., 426:830-842, 2014
Cited by
PubMed: 24295899
DOI: 10.1016/j.jmb.2013.11.021
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.23 Å)
Structure validation

217705

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