6SNI
 
 | | Cryo-EM structure of nanodisc reconstituted yeast ALG6 in complex with 6AG9 Fab | | 分子名称: | 6AG9-Fab heavy chain, 6AG9-Fab light chain, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Bloch, J.S, Pesciullesi, G, Boilevin, J, Nosol, K, Irobalieva, R.N, Darbre, T, Aebi, M, Kossiakoff, A.A, Reymond, J.L, Locher, K.P. | | 登録日 | 2019-08-24 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure and mechanism of the ER-based glucosyltransferase ALG6.
Nature, 579, 2020
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6SNH
 | | Cryo-EM structure of yeast ALG6 in complex with 6AG9 Fab and Dol25-P-Glc | | 分子名称: | 6AG9 Fab heavy chain, 6AG9 Fab light chain, Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase, ... | | 著者 | Bloch, J.S, Pesciullesi, G, Boilevin, J, Nosol, K, Irobalieva, R.N, Darbre, T, Aebi, M, Kossiakoff, A.A, Reymond, J.L, Locher, K.P. | | 登録日 | 2019-08-24 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure and mechanism of the ER-based glucosyltransferase ALG6.
Nature, 579, 2020
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4XTR
 | | Structure of Get3 bound to the transmembrane domain of Pep12 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ... | | 著者 | Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J. | | 登録日 | 2015-01-23 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
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4XVU
 | | Structure of Get3 bound to the transmembrane domain of Nyv1 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Antibody heavy chain, ... | | 著者 | Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J. | | 登録日 | 2015-01-28 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
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4XH2
 | | Crystal structure of human paxillin LD4 motif in complex with Fab fragment | | 分子名称: | ACETATE ION, ACETYL GROUP, Fab Heavy Chain, ... | | 著者 | Nocula-Lugowska, M, Lugowski, M, Salgia, R, Kossiakoff, A.A. | | 登録日 | 2015-01-04 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
J.Mol.Biol., 427, 2015
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4XMN
 | | Structure of the yeast coat nucleoporin complex, space group P212121 | | 分子名称: | Antibody 87 heavy chain, Antibody 87 light chain, Nucleoporin NUP120, ... | | 著者 | Stuwe, T, Correia, A.R, Lin, D.H, Paduch, M, Lu, V.T, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2015-01-14 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (7.6 Å) | | 主引用文献 | Nuclear pores. Architecture of the nuclear pore complex coat.
Science, 347, 2015
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4XWO
 | | Structure of Get3 bound to the transmembrane domain of Sec22 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ... | | 著者 | Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J. | | 登録日 | 2015-01-29 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
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4XMM
 | | Structure of the yeast coat nucleoporin complex, space group C2 | | 分子名称: | Antibody 57 heavy chain, Antibody 57 light chain, Nucleoporin NUP120, ... | | 著者 | Stuwe, T, Correia, A.R, Lin, D.H, Paduch, M, Lu, V.T, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2015-01-14 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (7.384 Å) | | 主引用文献 | Nuclear pores. Architecture of the nuclear pore complex coat.
Science, 347, 2015
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4XGZ
 | | Crystal structure of human paxillin LD2 motif in complex with Fab fragment | | 分子名称: | 1,2-ETHANEDIOL, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... | | 著者 | Nocula-Lugowska, M, Lugowski, M, Salgia, R, Kossiakoff, A.A. | | 登録日 | 2015-01-04 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
J.Mol.Biol., 427, 2015
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1Y3T
 | | Crystal structure of YxaG, a dioxygenase from Bacillus subtilis | | 分子名称: | FE (III) ION, Hypothetical protein yxaG | | 著者 | Gopal, B, Madan, L.L, Betz, S.F, Kossiakoff, A.A. | | 登録日 | 2004-11-26 | | 公開日 | 2005-01-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Crystal Structure of a Quercetin 2,3-Dioxygenase from Bacillus subtilis Suggests Modulation of Enzyme Activity by a Change in the Metal Ion at the Active Site(s)
Biochemistry, 44, 2005
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1YIW
 | | X-ray Crystal Structure of a Chemically Synthesized Ubiquitin | | 分子名称: | CADMIUM ION, CHLORIDE ION, Ubiquitin | | 著者 | Bang, D, Makhatadze, G.I, Tereshko, V, Kossiakoff, A.A, Kent, S.B. | | 登録日 | 2005-01-13 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
Angew.Chem.Int.Ed.Engl., 44, 2005
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1YJ1
 | | X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin | | 分子名称: | CADMIUM ION, CHLORIDE ION, Ubiquitin | | 著者 | Bang, D, Makhatadze, G.I, Tereshko, V, Kossiakoff, A.A, Kent, S.B. | | 登録日 | 2005-01-13 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
Angew.Chem.Int.Ed.Engl., 44, 2005
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6U8C
 | | Crystal structure of an engineered ultra-high affinity Fab-Protein G complex | | 分子名称: | Antibody heavy chain Fab, Antibody light chain Fab, Protein G | | 著者 | Slezak, T, Filippova, E.V, Davydova, E.K, Kossiakoff, A.A. | | 登録日 | 2019-09-04 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.
Protein Sci., 29, 2020
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7PTI
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6UKJ
 | | Single-Particle Cryo-EM Structure of Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT) 7G8 Isoform | | 分子名称: | CHOLESTEROL HEMISUCCINATE, Chloroquine resistance transporter, Fab Heavy Chain, ... | | 著者 | Kim, J, Tan, Y.Z, Wicht, K.J, Erramilli, S.K, Dhingra, S.K, Okombo, J, Vendome, J, Hagenah, L.M, Giacometti, S.I, Warren, A.L, Nosol, K, Roepe, P.D, Potter, C.S, Carragher, B, Kossiakoff, A.A, Quick, M, Fidock, D.A, Mancia, F. | | 登録日 | 2019-10-05 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.
Nature, 576, 2019
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6USF
 | | CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor with varenicline in complex with anti-BRIL synthetic antibody BAK5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, ... | | 著者 | Alvarez, F.J.D, Mukherjee, S, Han, S, Ammirati, M, Kossiakoff, A.A. | | 登録日 | 2019-10-26 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
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6UR8
 | | CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor in complex with varenicline | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chimera of soluble cytochrome b562 (BRIL) and neuronal acetylcholine receptor subunit alpha-4, Neuronal acetylcholine receptor subunit beta-2, ... | | 著者 | Alvarez, F.J.D, Mukherjee, S, Han, S, Ammirati, M, Kossiakoff, A.A. | | 登録日 | 2019-10-22 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
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5BK2
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5C8J
 | | A YidC-like protein in the archaeal plasma membrane | | 分子名称: | Antibody fragment, heavy chain, light chain, ... | | 著者 | Borowska, M.T, Dominik, P.K, Anghel, S.A, Kossiakoff, A.A, Keenan, R.J. | | 登録日 | 2015-06-25 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.502 Å) | | 主引用文献 | A YidC-like Protein in the Archaeal Plasma Membrane.
Structure, 23, 2015
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5BK1
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5BJZ
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6B6Z
 | | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) | | 分子名称: | Apo Fab Heavy Chain, Apo Fab Light Chain, ZINC ION | | 著者 | Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S. | | 登録日 | 2017-10-03 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.112 Å) | | 主引用文献 | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
To Be Published
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6AZ2
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6AYZ
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6BF8
 | | Cryo-EM structure of human insulin degrading enzyme in complex with insulin | | 分子名称: | Insulin-degrading enzyme | | 著者 | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | | 登録日 | 2017-10-26 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
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