8TTF
 
 | | NorA double mutant - E222QD307N at pH 7.5 | | 分子名称: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | | 主引用文献 | NorA double mutant - E222QD307N at pH 7.5
To Be Published
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8TTE
 | | Protonated state of NorA at pH 5.0 | | 分子名称: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Protonated state of NorA at pH 5.0
To Be Published
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2KIR
 | | Solution structure of a designer toxin, mokatoxin-1 | | 分子名称: | Designer toxin | | 著者 | Biancalana, M, Koide, A, Takacs, Z, Goldstein, S, Koide, S. | | 登録日 | 2009-05-07 | | 公開日 | 2009-12-29 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2I5Z
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2HKD
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7L0G
 | | Monobody 12VC1 Bound to HRAS(G12C) | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Teng, K.W, Hattori, T, Tsai, S, Koide, S. | | 登録日 | 2020-12-11 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Nat Commun, 12, 2021
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7L0F
 | | Monobody 12VC3 Bound to HRAS(WT) | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Teng, K.W, Hattori, T, Tsai, S, Koide, S. | | 登録日 | 2020-12-11 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Nat Commun, 12, 2021
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5CWU
 | | Crystal structure of Chaetomium thermophilum Nup188 TAIL domain | | 分子名称: | GLYCEROL, Nucleoporin NUP188 | | 著者 | Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2015-07-28 | | 公開日 | 2015-09-16 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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5CWV
 | | Crystal structure of Chaetomium thermophilum Nup192 TAIL domain | | 分子名称: | Nucleoporin NUP192 | | 著者 | Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2015-07-28 | | 公開日 | 2015-09-16 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (3.155 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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5CWW
 | | Crystal structure of the Chaetomium thermophilum heterotrimeric Nup82 NTD-Nup159 TAIL-Nup145N APD complex | | 分子名称: | Nucleoporin NUP145N, Nucleoporin NUP159, Nucleoporin NUP82 | | 著者 | Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2015-07-28 | | 公開日 | 2015-09-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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7JW7
 | | Structure of monobody 27 human MLKL pseudokinase domain complex | | 分子名称: | Mixed lineage kinase domain-like protein, Monobody 27 | | 著者 | Meng, Y, Garnish, S.E, Koide, A, Koide, S, Czabotar, P.E, Murphy, J.M. | | 登録日 | 2020-08-25 | | 公開日 | 2021-03-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis.
Nat Commun, 12, 2021
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7JXU
 | | Structure of monobody 32 human MLKL pseudokinase domain complex | | 分子名称: | 1,2-ETHANEDIOL, Mixed lineage kinase domain-like protein, Monobody 32 | | 著者 | Meng, Y, Garnish, S.E, Koide, A, Koide, S, Czabotar, P.E, Murphy, J.M. | | 登録日 | 2020-08-28 | | 公開日 | 2021-03-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis.
Nat Commun, 12, 2021
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4YHP
 | | Crystal structure of 309M3-B Fab in complex with H3K9me3 peptide | | 分子名称: | Fab Heavy Chain, Fab Light Chain, H3K9me3 peptide | | 著者 | Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S. | | 登録日 | 2015-02-27 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4YHY
 | | Crystal structure of 309M3-B in complex with trimethylated Lys | | 分子名称: | Fab Heavy Chain, Fab Light Chain, N-TRIMETHYLLYSINE | | 著者 | Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S. | | 登録日 | 2015-02-27 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4YHZ
 | | Crystal structure of 304M3-B Fab in complex with H3K4me3 peptide | | 分子名称: | Fab Heavy Chain, Fab Light Chain, GLYCEROL, ... | | 著者 | Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S. | | 登録日 | 2015-02-27 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.304 Å) | | 主引用文献 | Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4JQI
 | | Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide | | 分子名称: | 1,2-ETHANEDIOL, Beta-arrestin-1, CHLORIDE ION, ... | | 著者 | Shukla, A.K, Manglik, A, Kruse, A.C, Xiao, K, Reis, R.I, Tseng, W.C, Staus, D.P, Hilger, D, Uysal, S, Huang, L.H, Paduch, M, Shukla, P.T, Koide, A, Koide, S, Weis, W.I, Kossiakoff, A.A, Kobilka, B.K, Lefkowitz, R.J. | | 登録日 | 2013-03-20 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Nature, 497, 2013
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3RZW
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3CSG
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3CSB
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5G15
 | | Structure Aurora A (122-403) bound to activating monobody Mb1 and AMPPCP | | 分子名称: | AURORA A KINASE, MAGNESIUM ION, MB1 MONOBODY, ... | | 著者 | Zorba, A, Kutter, S, Kern, D, Koide, S, Koide, A. | | 登録日 | 2016-03-23 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Allosteric modulation of a human protein kinase with monobodies.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6BYN
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5MTN
 | | Monobody Mb(Lck_1) bound to Lck-Sh2 | | 分子名称: | Monobody Mb(Lck_1), SULFATE ION, Tyrosine-protein kinase Lck | | 著者 | Pojer, F, Kukenshoner, T, Koide, S, Hantschel, O. | | 登録日 | 2017-01-10 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.
J. Mol. Biol., 429, 2017
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5MTJ
 | | Yes1-SH2 in complex with monobody Mb(Yes_1) | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Monobody Mb(Yes_1), SULFATE ION, ... | | 著者 | Sha, F, Kukenshoner, T, Koide, S, Hantschel, O. | | 登録日 | 2017-01-09 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | | 主引用文献 | Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.
J. Mol. Biol., 429, 2017
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5MTM
 | | Monobody Mb(Lck_3) bound to Lck-SH2 domain | | 分子名称: | Monobody Mb(Lck_3), Tyrosine-protein kinase Lck, ZINC ION | | 著者 | Pojer, F, Kukenshoner, T, Koide, S, Hantschel, O. | | 登録日 | 2017-01-10 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | | 主引用文献 | Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.
J. Mol. Biol., 429, 2017
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4JE4
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