6BYN
Crystal structure of WDR5-Mb(S4) monobody complex
Summary for 6BYN
Entry DOI | 10.2210/pdb6byn/pdb |
Descriptor | WD repeat-containing protein 5, WDR5-binding Monobody, Mb(S4) (3 entities in total) |
Functional Keywords | beta-propeller, fibronectin, mll1, inhibitor, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 44087.89 |
Authors | |
Primary citation | Gupta, A.,Xu, J.,Lee, S.,Tsai, S.T.,Zhou, B.,Kurosawa, K.,Werner, M.S.,Koide, A.,Ruthenburg, A.J.,Dou, Y.,Koide, S. Facile target validation in an animal model with intracellularly expressed monobodies. Nat. Chem. Biol., 14:895-900, 2018 Cited by PubMed: 30013062DOI: 10.1038/s41589-018-0099-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.69 Å) |
Structure validation
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