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7LET
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BU of 7let by Molmil
Structure of importin a2 bound to the p50- and p65-NLSs
分子名称: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-15
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LEQ
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BU of 7leq by Molmil
Structure of importin a2 bound to p50 NLS
分子名称: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-14
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
8URW
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BU of 8urw by Molmil
Cyanobacterial RNA polymerase elongation complex with NusG and CTP
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA (40-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Qayyum, M.Z, Imashimizu, M, Leanca, M, Vishwakarma, R.K, Bradley Riaz, A, Yuzenkova, Y, Murakami, K.S.
登録日2023-10-26
公開日2023-12-27
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024
7SZ6
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BU of 7sz6 by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-3
分子名称: Portal protein
著者Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
登録日2021-11-25
公開日2022-03-30
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (6.24 Å)
主引用文献Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7SZ4
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BU of 7sz4 by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-2
分子名称: Portal protein
著者Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
登録日2021-11-25
公開日2022-03-30
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7SYA
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BU of 7sya by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length
分子名称: Portal protein
著者Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
登録日2021-11-24
公開日2022-04-20
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7SXK
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BU of 7sxk by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length
分子名称: Portal protein
著者Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
登録日2021-11-23
公開日2022-04-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7N9H
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BU of 7n9h by Molmil
Structure of the mammalian importin a1 bound to the TDP-43 NLS
分子名称: Importin subunit alpha-1, TAR DNA-binding protein 43
著者Doll, S.G, Lokareddy, R.K, Cingolani, G.
登録日2021-06-17
公開日2022-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
5HUY
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BU of 5huy by Molmil
Structure of HCMV Small Terminase NLS bound to importin alpha
分子名称: HCMV small terminase, Importin subunit alpha-1
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2016-01-28
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.979 Å)
主引用文献Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
5HUW
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BU of 5huw by Molmil
Structure of HSV-1 Large Terminase NLS bound to importin alpha
分子名称: HSV1 large terminase NLS, Importin subunit alpha-1
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2016-01-27
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
5T94
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BU of 5t94 by Molmil
Crystal structure of Kap60 bound to yeast RCC1 (Prp20)
分子名称: Guanine nucleotide exchange factor SRM1, Importin subunit alpha
著者Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
登録日2016-09-09
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.631 Å)
主引用文献Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
5TBK
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BU of 5tbk by Molmil
Crystal structure of human importin a3 bound to RCC1
分子名称: Importin subunit alpha-3, Regulator of chromosome condensation
著者Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
登録日2016-09-12
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
5V5P
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BU of 5v5p by Molmil
Structure of NLS2R of influenza A virus nucleoprotein bound to importin alpha
分子名称: Importin subunit alpha-1, Nucleoprotein
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2017-03-14
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
5V5O
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BU of 5v5o by Molmil
Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha
分子名称: Importin subunit alpha-1, Nucleoprotein
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2017-03-14
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.243 Å)
主引用文献Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
4QLP
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BU of 4qlp by Molmil
Atomic structure of tuberculosis necrotizing toxin (TNT) complexed with its immunity factor IFT
分子名称: Alanine and proline rich protein, tuberculosis necrotizing toxin (TNT), immunity factor IFT
著者Cingolani, G, Lokareddy, R.K, Sun, J, Siroy, A, Speer, A, Doornbos, K.S, Niederweis, M.
登録日2014-06-12
公開日2015-07-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD.
Nat.Struct.Mol.Biol., 22, 2015
6RGV
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BU of 6rgv by Molmil
Truncated FljB phase 2 flagellin
分子名称: Flagellin
著者Lunelli, M, Lokareddy, R.K, Kolbe, M.
登録日2019-04-17
公開日2020-03-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion.
Nat Commun, 11, 2020
4MBB
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BU of 4mbb by Molmil
Cubic crystal form of PIR1 dual specificity phosphatase core
分子名称: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2013-08-19
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
4NYH
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BU of 4nyh by Molmil
Orthorhombic crystal form of pir1 dual specificity phosphatase core
分子名称: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2013-12-10
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
3GYZ
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BU of 3gyz by Molmil
Crystal structure of IpgC from Shigella flexneri
分子名称: Chaperone protein ipgC, GLYCEROL, SODIUM ION, ...
著者Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M.
登録日2009-04-06
公開日2009-06-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
3GZ1
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BU of 3gz1 by Molmil
Crystal structure of IpgC in complex with the chaperone binding region of IpaB
分子名称: Chaperone protein ipgC, GLYCEROL, Invasin ipaB
著者Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M.
登録日2009-04-06
公開日2009-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
6VI1
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BU of 6vi1 by Molmil
Structure of Fab4 bound to P22 TerL(1-33)
分子名称: Synthetic Fab4 heavy chain, Synthetic Fab4 light chain, Terminase, ...
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-01-11
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6VI2
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BU of 6vi2 by Molmil
Structure of the unaligned Fab4
分子名称: FAB4 heavy chain, FAB4 light chain
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-01-11
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
8DKR
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BU of 8dkr by Molmil
Pseudomonas-phage E217 TerL nuclease domain
分子名称: Large terminase protein, MAGNESIUM ION
著者Cingolani, G, Lokareddy, R, Hou, D.
登録日2022-07-06
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Terminase Subunits from the Pseudomonas-Phage E217.
J.Mol.Biol., 434, 2022
6XMI
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BU of 6xmi by Molmil
Structure of Fab4 bound to P22 TerL(1-33)
分子名称: Fab Heavy chain, Fab Light chain, Terminase, ...
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-06-30
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6TK1
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BU of 6tk1 by Molmil
Femtosecond to millisecond structural changes in a light-driven sodium pump: 20ms structure of KR2 with extrapolated, light and dark datasets
分子名称: EICOSANE, RETINAL, SODIUM ION, ...
著者Skopintsev, P, Ehrenberg, D, Weinert, T, James, D, Kar, R, Johnson, P, Ozerov, D, Furrer, A, Martiel, I, Dworkowski, F, Nass, K, Knopp, G, Cirelli, C, Gashi, D, Mous, S, Wranik, M, Gruhl, T, Kekilli, D, Bruenle, S, Deupi, X, Schertler, G.F.X, Benoit, R, Panneels, V, Nogly, P, Schapiro, I, Milne, C, Heberle, J, Standfuss, J.
登録日2019-11-28
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Femtosecond-to-millisecond structural changes in a light-driven sodium pump.
Nature, 583, 2020

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