4NYH

Orthorhombic crystal form of pir1 dual specificity phosphatase core

Summary for 4NYH

• Entry DOI: 10.2210/pdb4nyh/pdb
• Related: 4MBB
• Descriptor: RNA/RNP complex-1-interacting phosphatase, PHOSPHATE ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: dual specificity phosphatase, protein tyrosine phosphatase, p-loop, protein tyrosine phosphatase (ptp)-fold, rna-rnp complex-1, dephosphorylation, nucleus, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O75319
• Total number of polymer chains: 3
• Total formula weight: 64093.92

Authors

Sankhala, R.S.,Lokareddy, R.K.,Cingolani, G. (deposition date: 2013-12-10, release date: 2014-01-08, Last modification date: 2024-02-28)

• Primary citation: Sankhala, R.S.,Lokareddy, R.K.,Cingolani, G.; Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.; Biochemistry, 53:862-871, 2014; PubMed: 24447265; DOI: 10.1021/bi401240x

Experimental method

X-RAY DIFFRACTION (1.2 Å)