4NYH
Orthorhombic crystal form of pir1 dual specificity phosphatase core
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | RNA/RNP complex-1-interacting phosphatase | polymer | 182 | 21234.2 | 3 | UniProt (O75319) Pfam (PF00782) | Homo sapiens (human) | Dual specificity protein phosphatase 11, Phosphatase that interacts with RNA/RNP complex 1 |
| 2 | D, F, H (A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 3 | E, G, I (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | J, K, L (A, B, C) | water | water | 18.0 | 831 | Chemie (HOH) |
Sequence modifications
A, B, C: 29 - 205 (UniProt: O75319)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Leu 26 | - | expression tag |
| Gly 27 | - | expression tag |
| Ser 28 | - | expression tag |
| Ser 152 | Cys 152 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 63702.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 391.3 | |
| All* | Total formula weight | 64093.9 |
