4NYH
Orthorhombic crystal form of pir1 dual specificity phosphatase core
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
| C | 0006470 | biological_process | protein dephosphorylation |
| C | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 A 301 |
| Chain | Residue |
| A | SER152 |
| A | HOH499 |
| A | THR153 |
| A | HIS154 |
| A | GLY155 |
| A | LEU156 |
| A | ASN157 |
| A | ARG158 |
| A | ARG192 |
| A | HOH445 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 302 |
| Chain | Residue |
| A | THR94 |
| A | TYR95 |
| A | THR96 |
| A | THR153 |
| A | ARG158 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B 301 |
| Chain | Residue |
| B | SER152 |
| B | THR153 |
| B | HIS154 |
| B | GLY155 |
| B | LEU156 |
| B | ASN157 |
| B | ARG158 |
| B | HOH430 |
| B | HOH544 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 302 |
| Chain | Residue |
| B | THR94 |
| B | TYR95 |
| B | THR96 |
| B | THR153 |
| B | ARG158 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 C 301 |
| Chain | Residue |
| C | SER152 |
| C | THR153 |
| C | HIS154 |
| C | GLY155 |
| C | LEU156 |
| C | ASN157 |
| C | ARG158 |
| C | HOH410 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 302 |
| Chain | Residue |
| C | THR94 |
| C | TYR95 |
| C | THR96 |
| C | THR153 |
| C | ARG158 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24447265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9685386","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24531476","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
