8JDZ
 
 | | Crystal structure of mLDHD in complex with 2-keto-3-methylvaleric acid | | 分子名称: | (3S)-3-methyl-2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDR
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxy-3-methyl-valeric acid | | 分子名称: | (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDU
 | | Crystal structure of mLDHD in complex with 2-ketovaleric acid | | 分子名称: | 2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDY
 | | Crystal structure of mLDHD in complex with 2-ketoisocaproic acid | | 分子名称: | 2-OXO-4-METHYLPENTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDF
 | | Crystal structure of H405A mLDHD in complex with D-lactate | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, Probable D-lactate dehydrogenase, ... | | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | | 登録日 | 2023-05-13 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDX
 | | Crystal structure of mLDHD in complex with 2-ketoisovaleric acid | | 分子名称: | 3-METHYL-2-OXOBUTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDE
 | | Crystal structure of mLDHD in complex with D-lactate | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, MANGANESE (II) ION, ... | | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | | 登録日 | 2023-05-13 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDO
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid | | 分子名称: | (2R)-2-hydroxyhexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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8JDP
 | | Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid | | 分子名称: | DEAMINOHYDROXYVALINE, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
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5FEK
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5FDJ
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5FEL
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8IQA
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8IL8
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8IX6
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4DQM
 | | Revealing a marine natural product as a novel agonist for retinoic acid receptors with a unique binding mode and antitumor activity | | 分子名称: | (5S)-4-[(3E,7E)-4,8-dimethyl-10-(2,6,6-trimethylcyclohex-1-en-1-yl)deca-3,7-dien-1-yl]-5-hydroxyfuran-2(5H)-one, Nuclear receptor coactivator 1, Retinoic acid receptor alpha | | 著者 | Wang, S, Wang, Z, Lin, S, Zheng, W, Wang, R, Jin, S, Chen, J, Jin, L, Li, Y. | | 登録日 | 2012-02-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells.
Biochem.J., 446, 2012
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7D7D
 | | CryoEM structure of gp45-dependent transcription activation complex | | 分子名称: | DNA (nontemplate strand), DNA (template strand), DNA polymerase clamp, ... | | 著者 | Shi, J, Wen, A, Jin, S, Feng, Y. | | 登録日 | 2020-10-03 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Transcription activation by a sliding clamp.
Nat Commun, 12, 2021
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7D7C
 | | CryoEM structure of gp55-dependent RNA polymerase-promoter open complex | | 分子名称: | DNA (nontemplate strand), DNA (template strand), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Shi, J, Wen, A, Jin, S, Feng, Y. | | 登録日 | 2020-10-03 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Transcription activation by a sliding clamp.
Nat Commun, 12, 2021
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1MRH
 | | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, ALPHA-MOMORCHARIN | | 著者 | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | | 登録日 | 1994-07-01 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins.
Biochem.J., 309, 1995
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1MRK
 | | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, ALPHA-TRICHOSANTHIN | | 著者 | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | | 登録日 | 1994-07-01 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins.
Biochem.J., 309, 1995
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1MRG
 | | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | | 分子名称: | ADENOSINE, ALPHA-MOMORCHARIN | | 著者 | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | | 登録日 | 1994-07-01 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins.
Biochem.J., 309, 1995
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1MRJ
 | | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | | 分子名称: | ADENOSINE, ALPHA-TRICHOSANTHIN | | 著者 | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | | 登録日 | 1994-07-01 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins.
Biochem.J., 309, 1995
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1MRI
 | | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | | 分子名称: | ALPHA-MOMORCHARIN | | 著者 | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | | 登録日 | 1994-07-01 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins.
Biochem.J., 309, 1995
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1S5O
 | | Structural and Mutational Characterization of L-carnitine Binding to Human carnitine Acetyltransferase | | 分子名称: | CARNITINE, carnitine acetyltransferase isoform 2 | | 著者 | Govindasamy, L, Kukar, T, Lian, W, Pedersen, B, Gu, Y, Agbandje-Mckenna, M, Jin, S, Mckenna, R, Wu, D. | | 登録日 | 2004-01-21 | | 公開日 | 2004-02-03 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase.
J.Struct.Biol., 146, 2004
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1T1U
 | | Structural Insights and Functional Implications of Choline Acetyltransferase | | 分子名称: | Choline O-acetyltransferase | | 著者 | Govindasamy, L, Pedersen, B, Lian, W, Kukar, T, Gu, Y, Jin, S, Agbandje-McKenna, M, Wu, D. | | 登録日 | 2004-04-18 | | 公開日 | 2005-04-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural insights and functional implications of choline acetyltransferase
J.Struct.Biol., 148, 2004
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