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1L8O
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BU of 1l8o by Molmil
Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase
分子名称: L-3-phosphoserine phosphatase, PHOSPHATE ION, SERINE
著者Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y.
登録日2002-03-21
公開日2003-04-01
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase
J.Biol.Chem., 277, 2002
1L8L
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BU of 1l8l by Molmil
Molecular basis for the local confomational rearrangement of human phosphoserine phosphatase
分子名称: D-2-AMINO-3-PHOSPHONO-PROPIONIC ACID, L-3-phosphoserine phosphatase
著者Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y.
登録日2002-03-21
公開日2003-04-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase.
J.Biol.Chem., 277, 2002
3NJ4
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BU of 3nj4 by Molmil
Fluoro-neplanocin A in Human S-Adenosylhomocysteine Hydrolase
分子名称: (4S,5S)-4-(6-amino-9H-purin-9-yl)-3-fluoro-5-hydroxy-2-(hydroxymethyl)cyclopent-2-en-1-one, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Jeong, L.S, Lee, K.M, Hwang, K.Y, Choi, S, Heo, Y.S.
登録日2010-06-17
公開日2011-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
J.Med.Chem., 54, 2011
7DHA
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BU of 7dha by Molmil
crystal structure of CD38 in complex with daratumumab
分子名称: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Heavy Chain, Light chain
著者Lee, H.T, Heo, Y.S.
登録日2020-11-13
公開日2021-09-22
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of CD38 in complex with daratumumab, a first-in-class anti-CD38 antibody drug for treating multiple myeloma.
Biochem.Biophys.Res.Commun., 536, 2021
7WJ5
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BU of 7wj5 by Molmil
Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand binding specificity
分子名称: Gai1 antibody (scfv16), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Heo, Y.S, Yoon, E.J, Jeon, Y.E, Yun, J.-H, Ishimoto, N, Woo, H, Park, S.Y, Song, J, Lee, W.T.
登録日2022-01-05
公開日2022-07-13
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Cryo-EM structure of the human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand-binding specificity.
Elife, 11, 2022
5Y9J
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BAFF in complex with belimumab
分子名称: Tumor necrosis factor ligand superfamily member 13B, belibumab light chain, belimumab heavy chain
著者Heo, Y.-S, Shin, W.
登録日2017-08-25
公開日2018-02-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Nat Commun, 9, 2018
5Y9K
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Structure of the belimumab Fab fragment
分子名称: belimumab heavy chain, belimumab light chain
著者Heo, Y.-S, Shin, W.
登録日2017-08-25
公開日2018-02-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Nat Commun, 9, 2018
7EOW
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High-resolution structure of vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine
分子名称: caplacizumab, von Willebrand factor
著者Lee, H.T, Heo, Y.-S.
登録日2021-04-23
公開日2021-07-07
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High-resolution structure of the vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine for treating acquired TTP.
Biochem.Biophys.Res.Commun., 567, 2021
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件を2025-07-09に公開中

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