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2LEH
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BU of 2leh by Molmil
Solution structure of the core SMN-Gemin2 complex
分子名称: Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1
著者Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G.
登録日2011-06-15
公開日2012-06-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the core SMN-Gemin2 complex.
Biochem.J., 445, 2012
4OT9
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BU of 4ot9 by Molmil
crystal structure of the C-terminal domain of p100/NF-kB2
分子名称: Nuclear factor NF-kappa-B p100 subunit, SULFATE ION
著者Tao, Z.H, Huang, D.B, Fusco, A, Gupta, K, Ware, C.F, Duynne, G.V.
登録日2014-02-13
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献p100/I kappa B delta sequesters and inhibits NF-kappa B through kappaBsome formation.
Proc.Natl.Acad.Sci.USA, 111, 2014
2M61
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BU of 2m61 by Molmil
NMR and Mass Spectrometric Studies of M-2 Branch Mini-M Conotoxins from Indian Cone Snails
分子名称: Conotoxin Ar1446
著者Sarma, S.P, Rajesh, R.P, Kumar, G.S, Sudarslal, S, Sabareesh, V, Gowd, K.H, Gupta, K, Krishnan, K.S, Balaram, P.
登録日2013-03-18
公開日2014-04-16
実験手法SOLUTION NMR
主引用文献NMR and Mass Spectrometric Studies of M-2 Branch Mini-M Conotoxins from Indian Cone Snails
To be Published
1EQG
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BU of 1eqg by Molmil
THE 2.6 ANGSTROM MODEL OF OVINE COX-1 COMPLEXED WITH IBUPROFEN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IBUPROFEN, PROSTAGLANDIN H2 SYNTHASE-1, ...
著者Loll, P.J, Selinsky, B.S, Gupta, K, Sharkey, C.T.
登録日2000-04-04
公開日2001-04-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations.
Biochemistry, 40, 2001
1EQH
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BU of 1eqh by Molmil
THE 2.7 ANGSTROM MODEL OF OVINE COX-1 COMPLEXED WITH FLURBIPROFEN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLURBIPROFEN, PROSTAGLANDIN H2 SYNTHASE-1, ...
著者Loll, P.J, Selinsky, B.S, Gupta, K, Sharkey, C.T.
登録日2000-04-04
公開日2001-04-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations.
Biochemistry, 40, 2001
5HRR
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BU of 5hrr by Molmil
HIV Integrase Catalytic Domain containing F185K + A124N + T125S mutations complexed with GSK0002
分子名称: (2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid, 1,2-ETHANEDIOL, CACODYLATE ION, ...
著者Nolte, R.T.
登録日2016-01-24
公開日2016-12-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
PLoS Biol., 14, 2016
5HRP
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BU of 5hrp by Molmil
HIV Integrase Catalytic Domain containing F185K + A124T mutations complexed with GSK0002
分子名称: (2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid, 1,2-ETHANEDIOL, CACODYLATE ION, ...
著者Nolte, R.T.
登録日2016-01-24
公開日2016-12-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
PLoS Biol., 14, 2016
5HRS
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BU of 5hrs by Molmil
HIV Integrase Catalytic Domain containing F185K + A124N + T125A mutations complexed with GSK0002
分子名称: (2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid, 1,2-ETHANEDIOL, CACODYLATE ION, ...
著者Nolte, R.T.
登録日2016-01-24
公開日2016-12-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
PLoS Biol., 14, 2016
5HRN
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BU of 5hrn by Molmil
HIV Integrase Catalytic Domain containing F185K mutation complexed with GSK0002
分子名称: (2S)-tert-butoxy[1-(3,4-difluorobenzyl)-6-methyl-4-(5-methyl-3,4-dihydro-2H-chromen-6-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]acetic acid, 1,2-ETHANEDIOL, CACODYLATE ION, ...
著者Nolte, R.T.
登録日2016-01-23
公開日2016-12-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
PLoS Biol., 14, 2016
6WXQ
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BU of 6wxq by Molmil
Crystal structure of CRISPR-associated transcription factor Csa3 complexed with cA4
分子名称: CRISPR-associated transcription factor Csa3 (Type I-A), GLYCEROL, cyclic tetraadenylate
著者Xia, P, Dutta, A, Parashar, V.
登録日2020-05-11
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems.
J.Biol.Chem., 298, 2022
3BVP
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BU of 3bvp by Molmil
Crystal Structure of the N-terminal Catalytic Domain of TP901-1 Integrase
分子名称: TP901-1 Integrase
著者Yuan, P, Van Duyne, G.D.
登録日2008-01-07
公開日2008-08-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tetrameric structure of a serine integrase catalytic domain.
Structure, 16, 2008
8EAX
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BU of 8eax by Molmil
Octameric prenyltransferase domain of fusicoccadiene Synthase with C2 symmetry sans transiently associating cyclase domains
分子名称: Fusicoccadiene synthase
著者Faylo, J.L, van Eeuwen, T, Christianson, D.W.
登録日2022-08-29
公開日2022-11-02
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Transient Prenyltransferase-Cyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase.
Biochemistry, 61, 2022
7QUR
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BU of 7qur by Molmil
SARS-CoV-2 Spike with ethylbenzamide-tri-iodo Siallyllactose, C3 symmetry
分子名称: 2,3,5-tris(iodanyl)benzamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Naismith, J.H, Yang, Y, Liu, J.W.
登録日2022-01-18
公開日2022-06-01
最終更新日2022-08-03
実験手法ELECTRON MICROSCOPY (2.27 Å)
主引用文献Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Science, 377, 2022
7QUS
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BU of 7qus by Molmil
SARS-CoV-2 Spike, C3 symmetry
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ...
著者Naismith, J.H, Yang, Y, Liu, J.W.
登録日2022-01-18
公開日2022-06-08
最終更新日2022-08-03
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Science, 377, 2022
6V0K
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BU of 6v0k by Molmil
Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha prenyltransferase domain
分子名称: GLYCEROL, Terpene synthase
著者Christianson, D.W, Ronnebaum, T.A.
登録日2019-11-18
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Higher-order oligomerization of a chimeric alpha beta gamma bifunctional diterpene synthase with prenyltransferase and class II cyclase activities is concentration-dependent.
J.Struct.Biol., 210, 2020
4GLI
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BU of 4gli by Molmil
Crystal Structure of Human SMN YG-Dimer
分子名称: Maltose-binding periplasmic protein, Survival motor neuron protein chimera
著者Martin, R.S, Perry, K, Van Duyne, G.D.
登録日2012-08-14
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献The survival motor neuron protein forms soluble glycine zipper oligomers.
Structure, 20, 2012
7TTR
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BU of 7ttr by Molmil
Skd3_ATPyS_FITC-casein Hexamer, AAA+ only
分子名称: ADENOSINE-5'-DIPHOSPHATE, Beta-casein, Caseinolytic peptidase B protein homolog, ...
著者Rizo, A.N.
登録日2022-02-01
公開日2022-09-28
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3.
Cell Rep, 40, 2022
7TTS
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BU of 7tts by Molmil
Skd3, hexamer, filtered
分子名称: ADENOSINE-5'-DIPHOSPHATE, Beta-casein, Caseinolytic peptidase B protein homolog, ...
著者Rizo, A.N, Cupo, R.R.
登録日2022-02-01
公開日2022-09-28
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3.
Cell Rep, 40, 2022
6N1K
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BU of 6n1k by Molmil
Full-length human phenylalanine hydroxylase (PAH) in the resting state
分子名称: CHLORIDE ION, FE (III) ION, Phenylalanine-4-hydroxylase
著者Arturo, E.C, Jaffe, E.K.
登録日2018-11-08
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.057 Å)
主引用文献Biophysical characterization of full-length human phenylalanine hydroxylase provides a deeper understanding of its quaternary structure equilibrium.
J.Biol.Chem., 294, 2019
8EDV
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BU of 8edv by Molmil
Mitoguardin homolog (MIGA) delta TM residues 106-496 from Caenorhabditis elegans bound to modelled lipid phosphatidylethanolamine
分子名称: DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, MItoGuArdin homolog
著者Hong, Z, Adlakha, J, Reinisch, K.M.
登録日2022-09-06
公開日2022-10-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Mitoguardin-2-mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation.
J.Cell Biol., 221, 2022
8C9N
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BU of 8c9n by Molmil
MiniCoV-ADDomer, a SARS-CoV-2 epitope presenting viral like particle
分子名称: Penton protein
著者Bufton, J.C, Capin, J, Boruku, U, Garzoni, F, Schaffitzel, C, Berger, I.
登録日2023-01-23
公開日2023-12-06
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.36 Å)
主引用文献In vitro generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2.
Antib Ther, 6, 2023
5G5J
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BU of 5g5j by Molmil
Crystal structure of human CYP3A4 bound to metformin
分子名称: CYTOCHROME P450 3A4, Metformin, PROTOPORPHYRIN IX CONTAINING FE
著者Sevrioukova, I.
登録日2016-05-25
公開日2017-06-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.
Cell Chem Biol, 24, 2017
8TRG
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BU of 8trg by Molmil
Structure of full-length LexA bound to a RecA filament
分子名称: DNA (27-MER), LexA repressor, MAGNESIUM ION, ...
著者Cory, M.B, Li, A, Kohli, R.M.
登録日2023-08-09
公開日2023-11-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献The LexA-RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation.
Nat.Struct.Mol.Biol., 2024
8QB3
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ADDobody zinc containing condition
分子名称: ADDobody, ZINC ION
著者Buzas, D, Toelzer, C, Berger, I, Schaffitzel, C.
登録日2023-08-24
公開日2023-12-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders.
Structure, 32, 2024
8QBX
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Chimeric Adenovirus-derived dodecamer
分子名称: Penton protein
著者Buzas, D, Borucu, U, Bufton, J, Kapadalakere, S.Y, Toelzer, C.
登録日2023-08-25
公開日2023-12-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders.
Structure, 32, 2024

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