2QU5
| Crystal structure of the VEGFR2 kinase domain in complex with a benzimidazole inhibitor | 分子名称: | 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide, Vascular endothelial growth factor receptor 2 | 著者 | Whittington, D.A, Kim, J.L, Long, A.M, Rose, P, Gu, Y, Zhao, H. | 登録日 | 2007-08-03 | 公開日 | 2007-09-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors. J.Med.Chem., 50, 2007
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1YY7
| Crystal structure of stringent starvation protein A (SspA), an RNA polymerase-associated transcription factor | 分子名称: | CITRIC ACID, stringent starvation protein A | 著者 | Hansen, A.-M, Gu, Y, Li, M, Andrykovitch, M, Waugh, D.S, Jin, D.J, Ji, X. | 登録日 | 2005-02-23 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structural basis for the function of stringent starvation protein A as a transcription factor J.Biol.Chem., 280, 2005
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2G1K
| Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimate at 1.75 angstrom resolution | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, CHLORIDE ION, SULFATE ION, ... | 著者 | Gan, J, Gu, Y, Li, Y, Yan, H, Ji, X. | 登録日 | 2006-02-14 | 公開日 | 2006-07-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue. Biochemistry, 45, 2006
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2G1J
| Crystal structure of Mycobacterium tuberculosis Shikimate Kinase at 2.0 angstrom resolution | 分子名称: | SULFATE ION, Shikimate kinase | 著者 | Gan, J, Gu, Y, Li, Y, Yan, H, Ji, X. | 登録日 | 2006-02-14 | 公開日 | 2006-07-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue. Biochemistry, 45, 2006
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8DK2
| CryoEM structure of Pseudomonas aeruginosa PA14 JetABC in an unclamped state trapped in ATP dependent dimeric form | 分子名称: | DNA (26-MER), JetA, JetB, ... | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | 登録日 | 2022-07-01 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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3EWH
| Crystal structure of the VEGFR2 kinase domain in complex with a pyridyl-pyrimidine benzimidazole inhibitor | 分子名称: | 1,2-ETHANEDIOL, N-[4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)naphthalen-1-yl]-6-(trifluoromethyl)-1H-benzimidazol-2-amine, vascular endothelial growth factor receptor 2 | 著者 | Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. | 登録日 | 2008-10-15 | 公開日 | 2009-08-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase. Bioorg.Med.Chem.Lett., 19, 2009
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8DK3
| CryoEM structure of Pseudomonas aeruginosa PA14 JetC ATPase domain bound to DNA and cWHD domain of JetA | 分子名称: | DNA (26-MER), JetA, JetC, ... | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | 登録日 | 2022-07-01 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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8DK1
| CryoEM structure of JetABC (head construct) from Pseudomonas aeruginosa PA14 | 分子名称: | JetA, JetB, JetC | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | 登録日 | 2022-07-01 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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1MRV
| crystal structure of an inactive Akt2 kinase domain | 分子名称: | RAC-beta serine/threonine kinase | 著者 | Huang, X, Begley, M, Morgenstern, K.A, Gu, Y, Rose, P, Zhao, H, Zhu, X. | 登録日 | 2002-09-18 | 公開日 | 2003-09-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of an inactive akt2 kinase domain Structure, 11, 2003
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1NM8
| Structure of Human Carnitine Acetyltransferase: Molecular Basis for Fatty Acyl Transfer | 分子名称: | Carnitine O-acetyltransferase | 著者 | Wu, D, Govindasamy, L, Lian, W, Gu, Y, Kukar, T, Agbandje-McKenna, M, McKenna, R. | 登録日 | 2003-01-09 | 公開日 | 2003-03-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of Human Carnitine Acetyltransferase. Molecular Basis for Fatty Acyl Transfer J.Biol.Chem., 278, 2003
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5JB1
| Pseudo-atomic structure of Human Papillomavirus Type 59 L1 Virus-like Particle | 分子名称: | Major capsid protein L1 | 著者 | Li, Z.H, Yan, X.D, Yu, H, Zheng, Q.B, Gu, Y, Li, S.W. | 登録日 | 2016-04-13 | 公開日 | 2016-05-18 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction. Structure, 24, 2016
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7TSX
| Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, Apo state | 分子名称: | Cap2, Cyclic AMP-AMP-GMP synthase | 著者 | Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | 登録日 | 2022-01-31 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature, 616, 2023
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7TSQ
| Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, AMP state | 分子名称: | ADENOSINE MONOPHOSPHATE, Cap2, Cyclic AMP-AMP-GMP synthase, ... | 著者 | Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | 登録日 | 2022-01-31 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature, 616, 2023
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5J6R
| Crystal structure of Human Papillomavirus Type 59 L1 pentamer | 分子名称: | Major capsid protein L1 | 著者 | Li, Z.H, Yan, X.D, Yu, H, Gu, Y, Li, S.W. | 登録日 | 2016-04-05 | 公開日 | 2016-05-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.011 Å) | 主引用文献 | The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction. Structure, 24, 2016
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1MRY
| crystal structure of an inactive akt2 kinase domain | 分子名称: | RAC-beta serine/threonine kinase | 著者 | Huang, X, Begley, M, Morgenstern, K.A, Gu, Y, Rose, P, Zhao, H, Zhu, X. | 登録日 | 2002-09-18 | 公開日 | 2003-09-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of an inactive akt2 kinase domain Structure, 11, 2003
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1S5O
| Structural and Mutational Characterization of L-carnitine Binding to Human carnitine Acetyltransferase | 分子名称: | CARNITINE, carnitine acetyltransferase isoform 2 | 著者 | Govindasamy, L, Kukar, T, Lian, W, Pedersen, B, Gu, Y, Agbandje-Mckenna, M, Jin, S, Mckenna, R, Wu, D. | 登録日 | 2004-01-21 | 公開日 | 2004-02-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase. J.Struct.Biol., 146, 2004
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1T1U
| Structural Insights and Functional Implications of Choline Acetyltransferase | 分子名称: | Choline O-acetyltransferase | 著者 | Govindasamy, L, Pedersen, B, Lian, W, Kukar, T, Gu, Y, Jin, S, Agbandje-McKenna, M, Wu, D. | 登録日 | 2004-04-18 | 公開日 | 2005-04-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural insights and functional implications of choline acetyltransferase J.Struct.Biol., 148, 2004
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7TIL
| CryoEM structure of JetD from Pseudomonas aeruginosa | 分子名称: | JetD | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | 登録日 | 2022-01-13 | 公開日 | 2022-10-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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8WSS
| Cryo-EM structure of Melanin-Concentrating Hormone Receptor 1 with MCH | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhao, L, He, Q, Yuan, Q, Gu, Y, Shan, H, Hu, W, Wu, K, Xu, H.E, Zhang, Y, Wu, C. | 登録日 | 2023-10-17 | 公開日 | 2024-06-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors. Cell Discov, 10, 2024
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8WST
| Cryo-EM structure of Melanin-Concentrating Hormone Receptor 2 with MCH | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha-1, ... | 著者 | Zhao, L, He, Q, Yuan, Q, Gu, Y, Shan, H, Hu, W, Wu, K, Xu, H.E, Zhang, Y, Wu, C. | 登録日 | 2023-10-17 | 公開日 | 2024-06-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors. Cell Discov, 10, 2024
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3GGQ
| Dimerization of Hepatitis E Virus Capsid Protein E2s Domain is Essential for Virus-Host Interaction | 分子名称: | BROMIDE ION, Capsid protein | 著者 | Li, S.W, Tang, X.H, Seetharaman, J, Yang, C.Y, Gu, Y, Zhang, J, Du, H.L, Shih, J.W.K, Hew, C.L, Sivaraman, J, Xia, N.S. | 登録日 | 2009-03-02 | 公開日 | 2009-08-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus-host interaction Plos Pathog., 5, 2009
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7SQV
| Goslar chimallin C1 localized reconstruction | 分子名称: | Chimallin | 著者 | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | 登録日 | 2021-11-06 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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7SQS
| 201phi2-1 Chimallin C1 localized reconstruction | 分子名称: | Chimallin | 著者 | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | 登録日 | 2021-11-06 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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7SQT
| Goslar chimallin cubic (O, 24mer) assembly | 分子名称: | Chimallin | 著者 | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | 登録日 | 2021-11-06 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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7SQQ
| 201Phi2-1 Chimallin Cubic (O, 24mer) assembly | 分子名称: | Chimallin | 著者 | Laughlin, T.G, Deep, A, Prichard, A.M, Seitz, C, Gu, Y, Enustun, E, Suslov, S, Khanna, K, Birkholz, E.A, Amaro, R.E, Pogliano, J, Corbett, K.D, Villa, E. | 登録日 | 2021-11-06 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Nature, 608, 2022
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