1MRV

crystal structure of an inactive Akt2 kinase domain

Summary for 1MRV

• Entry DOI: 10.2210/pdb1mrv/pdb
• Related: 1MRY
• Descriptor: RAC-beta serine/threonine kinase (2 entities in total)
• Functional Keywords: agc serine threonine kinase, akt pkb kinase domain, tumorigenesis, x-ray crystal structure, signal transduction, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39313.01

Authors

Huang, X.,Begley, M.,Morgenstern, K.A.,Gu, Y.,Rose, P.,Zhao, H.,Zhu, X. (deposition date: 2002-09-18, release date: 2003-09-23, Last modification date: 2024-04-03)

• Primary citation: Huang, X.,Begley, M.,Morgenstern, K.A.,Gu, Y.,Rose, P.,Zhao, H.,Zhu, X.; Crystal structure of an inactive akt2 kinase domain; Structure, 11:21-30, 2003; PubMed: 12517337; DOI: 10.1016/S0969-2126(02)00937-1

Experimental method

X-RAY DIFFRACTION (2.8 Å)