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3WJK
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Crystal structure of Octaprenyl Pyrophosphate synthase from Escherichia coli
分子名称: Octaprenyl diphosphate synthase
著者Han, X, Chen, C.C, Kuo, C.J, Huang, C.H, Zheng, Y, Ko, T.P, Zhu, Z, Feng, X, Oldfield, E, Liang, P.H, Guo, R.T, Ma, Y.H.
登録日2013-10-11
公開日2014-06-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms.
Proteins, 83, 2015
3WJN
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Crystal structure of Octaprenyl Pyrophosphate synthase from Escherichia coli with farnesyl S-thiol-pyrophosphate (FSPP)
分子名称: Octaprenyl diphosphate synthase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
著者Han, X, Chen, C.C, Kuo, C.J, Huang, C.H, Zheng, Y, Ko, T.P, Zhu, Z, Feng, X, Oldfield, E, Liang, P.H, Guo, R.T, Ma, Y.H.
登録日2013-10-12
公開日2014-06-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms.
Proteins, 83, 2015
3WJO
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BU of 3wjo by Molmil
Crystal structure of Octaprenyl Pyrophosphate synthase from Escherichia coli with isopentenyl pyrophosphate (IPP)
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Octaprenyl diphosphate synthase
著者Han, X, Chen, C.C, Kuo, C.J, Huang, C.H, Zheng, Y, Ko, T.P, Zhu, Z, Feng, X, Oldfield, E, Liang, P.H, Guo, R.T, Ma, Y.H.
登録日2013-10-12
公開日2014-06-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms.
Proteins, 83, 2015
4Z2Z
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BU of 4z2z by Molmil
New crystal structure of yeast Ddi1 aspartyl protease reveals substrate engagement mode
分子名称: DNA damage-inducible protein 1
著者Trempe, J.-F, Feng, X, Gehring, K.
登録日2015-03-30
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.
Sci Rep, 6, 2016
7L6N
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BU of 7l6n by Molmil
The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with three locally refined ClpB middle domains and three DnaK nucleotide binding domains
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, Chaperone protein DnaK, ...
著者Yin, Y.Y, Feng, X, Li, H.
登録日2020-12-23
公開日2021-05-26
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Cell Rep, 35, 2021
3WQM
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BU of 3wqm by Molmil
Crystal structure of Rv3378c with inhibitor BPH-629
分子名称: Diterpene synthase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T.
登録日2014-01-28
公開日2014-02-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis.
J.Am.Chem.Soc., 136, 2014
3WE9
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The crystal structure of YisP from Bacillus subtilis subsp. subtilis strain 168
分子名称: Putative phytoene/squalene synthase YisP, TRIETHYLENE GLYCOL
著者Hu, Y, Huang, C.H, Chan, H.C, Ko, T.P, Feng, X, Oldfield, E, Guo, R.T.
登録日2013-07-02
公開日2014-07-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structure of Bacillus subtilis YisP in complex with a PEG fragment
To be Published
7UQK
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BU of 7uqk by Molmil
Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase histone chaperone YTA7
著者Wang, F, Feng, X, Li, H.
登録日2022-04-19
公開日2023-02-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly.
J.Biol.Chem., 299, 2022
7UQJ
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Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ATPgS and histone H3 tail in state II
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase histone chaperone YTA7, Histone H3, ...
著者Wang, F, Feng, X, Li, H.
登録日2022-04-19
公開日2023-02-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly.
J.Biol.Chem., 299, 2022
7UQI
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BU of 7uqi by Molmil
Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase histone chaperone YTA7
著者Wang, F, Feng, X, Li, H.
登録日2022-04-19
公開日2023-02-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly.
J.Biol.Chem., 299, 2022
3WQK
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BU of 3wqk by Molmil
Crystal structure of Rv3378c with PO4
分子名称: Diterpene synthase, PHOSPHATE ION
著者Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T.
登録日2014-01-28
公開日2014-02-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis.
J.Am.Chem.Soc., 136, 2014
3WQN
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BU of 3wqn by Molmil
Crystal structure of Rv3378c_Y51F with TPP
分子名称: (2E)-3-methyl-5-[(1R,2S,8aS)-1,2,5,5-tetramethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, Diterpene synthase, PHOSPHATE ION
著者Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T.
登録日2014-01-28
公開日2014-02-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis.
J.Am.Chem.Soc., 136, 2014
3WQL
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BU of 3wql by Molmil
Crystal structure of Rv3378c with Mg2+ and PPi
分子名称: Diterpene synthase, MAGNESIUM ION
著者Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T.
登録日2014-01-28
公開日2014-02-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis.
J.Am.Chem.Soc., 136, 2014
5DIV
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BU of 5div by Molmil
The Fk1 domain of FKBP51 in complex with the new synthetic ligand (S)-N-(1-carbamoylcyclopentyl)-1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxamide
分子名称: (2S)-N-(1-carbamoylcyclopentyl)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxamide, Peptidyl-prolyl cis-trans isomerase FKBP5
著者Gaali, S, Feng, X, Sippel, C, Bracher, A, Hausch, F.
登録日2015-09-01
公開日2016-03-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51.
J.Med.Chem., 59, 2016
5DIU
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BU of 5diu by Molmil
The Fk1 domain of FKBP51 in complex with the new synthetic ligand 2-(3-((R)-1-((S)-1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxamido)-3-(3,4-dimethoxyphenyl)propyl)phenoxy)acetic acid
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, {3-[(1R)-1-[({(2S)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidin-2-yl}carbonyl)amino]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid
著者Gaali, S, Feng, X, Sippel, C, Bracher, A, Hausch, F.
登録日2015-09-01
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51.
J.Med.Chem., 59, 2016
8JKN
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BU of 8jkn by Molmil
T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAAA motif
分子名称: GAAA-Forward, GAAA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKO
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T95R mutant IRF4 DNA-binding domain bound to an DNA containing GATA motif
分子名称: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKL
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BU of 8jkl by Molmil
IRF4 DNA-binding domain bound to an DNA containing GATA motif
分子名称: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKQ
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T95R mutant IRF4 DNA-binding domain bound to an DNA containing GACA motif
分子名称: GACA-Forward, GACA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKS
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BU of 8jks by Molmil
T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAGA motif
分子名称: GAGA-Forward, GAGA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
7EER
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BU of 7eer by Molmil
Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with 05E6 and ATP
分子名称: 2-(1H-indol-3-yl)ethanol, ADENOSINE-5'-TRIPHOSPHATE, Tryptophan--tRNA ligase
著者Lv, G, Fan, S, Feng, X, Zhang, Q, Wu, G, Jin, Y, Yang, Z.
登録日2021-03-19
公開日2022-05-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with O5E6 and ATP
To Be Published
5WH5
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BU of 5wh5 by Molmil
Crystal structure of the PDE4D2 catalytic domain in complex with inhibitor (R)-Zl-n-91
分子名称: 1-[4-(difluoromethoxy)-3-{[(3R)-oxolan-3-yl]oxy}phenyl]-3-methylbutan-1-one, MAGNESIUM ION, ZINC ION, ...
著者Wang, H.
登録日2017-07-14
公開日2018-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Identification of a PDE4-Specific Pocket for the Design of Selective Inhibitors.
Biochemistry, 57, 2018
5WH6
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BU of 5wh6 by Molmil
Crystal structure of PDE4D2 in complex with inhibitor (S_Zl-n-91)
分子名称: 1-[4-(difluoromethoxy)-3-{[(3S)-oxolan-3-yl]oxy}phenyl]-3-methylbutan-1-one, MAGNESIUM ION, ZINC ION, ...
著者Ke, H, Wang, H.
登録日2017-07-14
公開日2018-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of a PDE4-Specific Pocket for the Design of Selective Inhibitors.
Biochemistry, 57, 2018
6LJH
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BU of 6ljh by Molmil
Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua in complex with NAD+
分子名称: Alcohol dehydrogenase 1, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Feng, X, Fan, S, Li, M, Zou, S, Lv, G, Wu, G, Jin, Y, Yang, Z.
登録日2019-12-16
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua in complex with NAD+
To Be Published
7CYI
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BU of 7cyi by Molmil
Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua
分子名称: Alcohol dehydrogenase 1, ZINC ION
著者Feng, X, Fan, S, Lv, G, Li, M, Wu, G, Jin, Y, Yang, Z.
登録日2020-09-03
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua
To Be Published

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