3WQN

Crystal structure of Rv3378c_Y51F with TPP

Summary for 3WQN

Entry DOI	10.2210/pdb3wqn/pdb
Related	3WQK 3WQL 3WQM
Descriptor	Diterpene synthase, PHOSPHATE ION, (2E)-3-methyl-5-[(1R,2S,8aS)-1,2,5,5-tetramethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, ... (4 entities in total)
Functional Keywords	diterpene synthase, hydrolase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	34766.94
Authors	Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. (deposition date: 2014-01-28, release date: 2014-02-26, Last modification date: 2024-03-20)
Primary citation	Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136:2892-2896, 2014 Cited by PubMed: 24475925 DOI: 10.1021/ja413127v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation