2XTP
 
 | |
2XTM
 | | Crystal structure of GDP-bound human GIMAP2, amino acid residues 1- 234 | | 分子名称: | GLYCEROL, GTPASE IMAP FAMILY MEMBER 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Schwefel, D, Froehlich, C, Daumke, O. | | 登録日 | 2010-10-11 | | 公開日 | 2010-10-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Basis of Oligomerization in Septin-Like Gtpase of Immunity-Associated Protein 2 (Gimap2)
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
2XTO
 | | Crystal structure of GDP-bound human GIMAP2, amino acid residues 21- 260 | | 分子名称: | GTPASE IMAP FAMILY MEMBER 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Schwefel, D, Froehlich, C, Daumke, O. | | 登録日 | 2010-10-11 | | 公開日 | 2010-10-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Basis of Oligomerization in Septin-Like Gtpase of Immunity-Associated Protein 2 (Gimap2)
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
7BI9
 | | PI3KC2a core in complex with PIK90 | | 分子名称: | 1,2-ETHANEDIOL, N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C] QUINAZOLIN-5-YL)NICOTINAMIDE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | | 著者 | Lo, W.T, Roske, Y, Daumke, O, Haucke, V. | | 登録日 | 2021-01-12 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural basis of phosphatidylinositol 3-kinase C2 alpha function.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7BI6
 | | PI3KC2a core in complex with ATP | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Lo, W.T, Roske, Y, Daumke, O, Haucke, V. | | 登録日 | 2021-01-12 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis of phosphatidylinositol 3-kinase C2 alpha function.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7BI4
 | | PI3KC2a core apo | | 分子名称: | 1,2-ETHANEDIOL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, SULFATE ION | | 著者 | Lo, W.T, Roske, Y, Daumke, O, Haucke, V. | | 登録日 | 2021-01-12 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structural basis of phosphatidylinositol 3-kinase C2 alpha function.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7BI2
 | | PI3KC2aDeltaN and DeltaC-C2 | | 分子名称: | 1,2-ETHANEDIOL, 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one, IODIDE ION, ... | | 著者 | Lo, W.T, Roske, Y, Daumke, O, Haucke, V. | | 登録日 | 2021-01-12 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural basis of phosphatidylinositol 3-kinase C2 alpha function.
Nat.Struct.Mol.Biol., 29, 2022
|
|
5MTV
 | | Active structure of EHD4 complexed with ATP-gamma-S | | 分子名称: | EH domain-containing protein 4, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Melo, A.A, Daumke, O. | | 登録日 | 2017-01-10 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5MVF
 | | Active structure of EHD4 complexed with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, EH domain-containing protein 4, MAGNESIUM ION | | 著者 | Melo, A.A, Daumke, O. | | 登録日 | 2017-01-16 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.268 Å) | | 主引用文献 | Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4CSG
 | |
4CSF
 | |
4CID
 | |
4Z0I
 | | Crystal structure of a tetramer of GluA2 ligand binding domains bound with glutamate at 1.45 Angstrom resolution | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLUTAMIC ACID, Glutamate receptor 2,Glutamate receptor 2, ... | | 著者 | Baranovic, J, Chebli, M, Salazar, H, Carbone, A.L, Ghisi, V, Faelber, K, Lau, A.Y, Daumke, O, Plested, A.J.R. | | 登録日 | 2015-03-26 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structure of the tetrameric wt GluA2 ligand-binding domain bound to glutamate at 1.45 Angstroms resolution
To Be Published
|
|
4YU0
 | | Crystal structure of a tetramer of GluA2 TR mutant ligand binding domains bound with glutamate at 1.26 Angstrom resolution | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLUTAMIC ACID, Glutamate receptor 2,Glutamate receptor 2, ... | | 著者 | Chebli, M, Salazar, H, Baranovic, J, Carbone, A.L, Ghisi, V, Faelber, K, Lau, A.Y, Daumke, O, Plested, A.J.R. | | 登録日 | 2015-03-18 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Crystal structure of the tetrameric GluA2 ligand-binding domain in complex with glutamate at 1.26 Angstroms resolution
To Be Published
|
|
4ZFO
 | | J22.9-xi: chimeric mouse/human antibody against human BCMA (CD269) | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, J22.9-xi Fab, ... | | 著者 | Marino, S.F, Daumke, O, Olal, D. | | 登録日 | 2015-04-21 | | 公開日 | 2015-05-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | | 主引用文献 | Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Mol Oncol, 9, 2015
|
|
4ZP3
 | | AKAP18:PKA-RIIalpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA | | 分子名称: | A-kinase anchor protein 7 isoforms alpha and beta, CADMIUM ION, cAMP-dependent protein kinase type II-alpha regulatory subunit | | 著者 | Goetz, F, Roske, Y, Faelber, K, Zuehlke, K, Autenrieth, K, Kreuchwig, A, Krause, G, Herberg, F.W, Daumke, O, Heinemann, U, Klussmann, E. | | 登録日 | 2015-05-07 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | AKAP18:PKA-RII alpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Biochem.J., 473, 2016
|
|
6YGB
 | | Crystal structure of the NatC complex bound to CoA | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... | | 著者 | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | | 登録日 | 2020-03-27 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.451 Å) | | 主引用文献 | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Nat Commun, 11, 2020
|
|
6YGA
 | | Crystal structure of the apo NatC complex | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | | 登録日 | 2020-03-27 | | 公開日 | 2020-10-28 | | 最終更新日 | 2020-11-18 | | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | | 主引用文献 | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Nat Commun, 11, 2020
|
|
6YGD
 | | Crystal structure of the NatC complex bound to Gag peptide and CoA | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... | | 著者 | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | | 登録日 | 2020-03-27 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.752 Å) | | 主引用文献 | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Nat Commun, 11, 2020
|
|
6Z3E
 | |
8Q1S
 | | Pathogenic mutations of human phosphorylation sites affect protein-protein interactions | | 分子名称: | 1,2-ETHANEDIOL, 14-3-3 protein epsilon, BROMIDE ION, ... | | 著者 | Roske, Y, Daumke, O, Rrustemi, T, Selbach, M. | | 登録日 | 2023-08-01 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | | 主引用文献 | Pathogenic mutations of human phosphorylation sites affect protein-protein interactions.
Nat Commun, 15, 2024
|
|
8R1A
 | | Model of the membrane-bound GBP1 oligomer | | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate binding protein 1, ... | | 著者 | Weismehl, M, Chu, X, Kutsch, M, Lauterjung, P, Herrmann, C, Kudryashev, M, Daumke, O. | | 登録日 | 2023-11-01 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (26.799999 Å) | | 主引用文献 | Structural insights into the activation mechanism of antimicrobial GBP1.
Embo J., 43, 2024
|
|
8Q1K
 | | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | | 著者 | Roske, Y, Daumke, O, Damme, M. | | 登録日 | 2023-07-31 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Nucleic Acids Res., 52, 2024
|
|
8Q1X
 | | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | | 著者 | Roske, Y, Daumke, O, Damme, M. | | 登録日 | 2023-08-01 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Nucleic Acids Res., 52, 2024
|
|
4FVJ
 | |
