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8AVF
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BU of 8avf by Molmil
Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (closed 3:3 model)
分子名称: Leptin, Leptin receptor
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (6.45 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AVC
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BU of 8avc by Molmil
Mouse leptin:LEP-R complex cryoEM structure (3:3 model)
分子名称: Leptin, Leptin receptor, NICKEL (II) ION
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AV2
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BU of 8av2 by Molmil
Crystal structure for the FnIII module of mouse LEP-R in complex with the anti-LEP-R nanobody VHH-4.80
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin receptor, SULFATE ION, ...
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AVE
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BU of 8ave by Molmil
Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (2:2 model)
分子名称: Leptin, Leptin receptor
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (5.62 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AVB
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BU of 8avb by Molmil
Cryo-EM structure for mouse leptin in complex with the mouse LEP-R ectodomain (1:2 mLEP:mLEPR model).
分子名称: Leptin, Leptin receptor
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.43 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8B7Q
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BU of 8b7q by Molmil
Cryo-EM structure for the mouse LEPR-CRH2:Leptin:LEPR-Ig complex following symmetry expansion in combination with local refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-09-30
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
6GKS
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BU of 6gks by Molmil
X-ray structure determined from recombinant Charcot-Leyden crystal
分子名称: GLYCEROL, Galectin-10
著者Verstraete, K, Verschueren, K, Savvides, S.N.
登録日2018-05-21
公開日2019-06-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GKQ
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BU of 6gkq by Molmil
X-ray structure determined from ex vivo Charcot-Leyden crystal
分子名称: GLYCEROL, Galectin-10
著者Verstraete, K, Verschueren, K, Savvides, S.N.
登録日2018-05-21
公開日2019-06-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6HXJ
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BU of 6hxj by Molmil
Structure of ATP citrate lyase from Chlorobium limicola in complex with citrate and coenzyme A.
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-citrate lyase alpha-subunit, ATP-citrate lyase beta-subunit, ...
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXH
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BU of 6hxh by Molmil
Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase,Human ATP citrate lyase, CITRATE ANION, ...
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXI
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BU of 6hxi by Molmil
Structure of ATP citrate lyase from Methanothrix soehngenii in complex with citrate and coenzyme A
分子名称: ACETATE ION, CITRATE ANION, COENZYME A, ...
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXP
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BU of 6hxp by Molmil
Structure of citryl-CoA lyase from Hydrogenobacter thermophilus
分子名称: COENZYME A, Citryl-CoA lyase, SULFATE ION
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXN
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BU of 6hxn by Molmil
Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P3121)
分子名称: ATP-citrate lyase alpha-subunit, COENZYME A, SULFATE ION
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXL
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BU of 6hxl by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH (space group P21)
分子名称: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXO
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BU of 6hxo by Molmil
Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P21)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ATP-citrate lyase alpha-subunit, CITRATE ANION
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXM
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BU of 6hxm by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221
分子名称: ATP-citrate synthase, CITRATE ANION, COENZYME A
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXK
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BU of 6hxk by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate
分子名称: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXQ
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BU of 6hxq by Molmil
Structure of citryl-CoA synthetase from Hydrogenobacter thermophilus
分子名称: CITRATE ANION, COENZYME A, Citryl-CoA synthetase large subunit, ...
著者Verstraete, K, Verschueren, K.
登録日2018-10-17
公開日2019-04-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
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