8HF8
 
 | | Human PPAR delta ligand binding domain in complex with a synthetic agonist V1 | | 分子名称: | 2-[4-[[2,5-bis(oxidanylidene)-3-[4-(trifluoromethyl)phenyl]imidazolidin-1-yl]methyl]-2,6-dimethyl-phenoxy]-2-methyl-propanoic acid, Peroxisome proliferator-activated receptor delta, octyl beta-D-glucopyranoside | | 著者 | Dai, L, Sun, H.B, Yuan, H.L, Feng, Z.Q. | | 登録日 | 2022-11-09 | | 公開日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Discovery of the First Subnanomolar PPAR alpha / delta Dual Agonist for the Treatment of Cholestatic Liver Diseases.
J.Med.Chem., 66, 2023
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8JI5
 | | Crystal structure of AetD in complex with 5-bromo-L-tryptophan and two Fe2+ | | 分子名称: | 5-bromo-L-tryptophan, AetD, FE (II) ION, ... | | 著者 | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-05-26 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | The structural and functional investigation into an unusual nitrile synthase.
Nat Commun, 14, 2023
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8JI4
 | | Crystal structure of AetD in complex with 5-bromo-L-tryptophan | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-bromo-L-tryptophan, AetD, ... | | 著者 | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-05-26 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | The structural and functional investigation into an unusual nitrile synthase.
Nat Commun, 14, 2023
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8JI3
 | | Crystal structure of AetD in complex with 5,7-dibromo-L-tryptophan and two Fe2+ | | 分子名称: | (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, AetD, FE (II) ION, ... | | 著者 | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-05-26 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | The structural and functional investigation into an unusual nitrile synthase.
Nat Commun, 14, 2023
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8JI6
 | | Crystal structure of AetD in complex with L-tryptophan | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AetD, FE (II) ION, ... | | 著者 | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-05-26 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structural and functional investigation into an unusual nitrile synthase.
Nat Commun, 14, 2023
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8JI7
 | | Crystal structure of AetD in complex with L-tryptophan and two Fe2+ | | 分子名称: | AetD, FE (II) ION, NICKEL (II) ION, ... | | 著者 | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-05-26 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | The structural and functional investigation into an unusual nitrile synthase.
Nat Commun, 14, 2023
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8JI2
 | | Crystal structure of AetD in complex with 5,7-dibromo-L-tryptophan | | 分子名称: | (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AetD, ... | | 著者 | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-05-26 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The structural and functional investigation into an unusual nitrile synthase.
Nat Commun, 14, 2023
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7F7M
 | | AKR4C17 in complex with NADP+ and glyphosate | | 分子名称: | AKR4-2, GLYPHOSATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Li, H, Yang, Y, Hu, Y, Chen, C.-C, Huang, J.-W, Min, J, Dai, L, Guo, R.-T. | | 登録日 | 2021-06-30 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona
J Hazard Mater, 436, 2022
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7F7L
 | | Crystal structure of AKR4C17 bound with NADPH | | 分子名称: | AKR4-2, COBALT (II) ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Li, H, Yang, Y, Hu, Y, Chen, C.-C, Huang, J.-W, Min, J, Dai, L, Guo, R.-T. | | 登録日 | 2021-06-30 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona
J Hazard Mater, 436, 2022
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7F7K
 | | Crystal structure of AKR4C17 bound with NADP+ | | 分子名称: | AKR4-2, COBALT (II) ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Li, H, Yang, Y, Hu, Y, Chen, C.-C, Huang, J.-W, Min, J, Dai, L, Guo, R.-T. | | 登録日 | 2021-06-30 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona
J Hazard Mater, 436, 2022
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7F7J
 | | The crystal structure of AKR4C17 | | 分子名称: | AKR4-2, COBALT (II) ION, SULFATE ION | | 著者 | Li, H, Yang, Y, Hu, Y, Chen, C.-C, Huang, J.-W, Min, J, Dai, L, Guo, R.-T. | | 登録日 | 2021-06-30 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colona
J Hazard Mater, 436, 2022
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6J5G
 | | Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein | | 分子名称: | Envelope protein E, antibody heavy chain, antibody light chain | | 著者 | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.291 Å) | | 主引用文献 | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus.
J. Virol., 93, 2019
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6J5C
 | | Louping ill virus envelope protein | | 分子名称: | Envelope protein E | | 著者 | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus.
J. Virol., 93, 2019
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6J5D
 | | Complex structure of MAb 4.2-scFv with louping ill virus envelope protein Domain III | | 分子名称: | Envelope, antibody heavy chain, antibody light chain | | 著者 | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus.
J. Virol., 93, 2019
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6J5F
 | | Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein Domain III | | 分子名称: | Envelope protein, antibody heavy chain, antibody light chain | | 著者 | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | | 登録日 | 2019-01-10 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus.
J. Virol., 93, 2019
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5GZN
 | | Structure of neutralizing antibody bound to Zika envelope protein | | 分子名称: | Antibody Heavy chain, Antibody light chain, Genome polyprotein | | 著者 | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2016-09-29 | | 公開日 | 2016-12-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
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5GZO
 | | Structure of neutralizing antibody bound to Zika envelope protein | | 分子名称: | Antibody heavy chain, Antibody light chain, Genome polyprotein | | 著者 | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2016-09-29 | | 公開日 | 2017-01-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
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4NFT
 | | Crystal structure of human lnkH2B-h2A.Z-Anp32e | | 分子名称: | Acidic leucine-rich nuclear phosphoprotein 32 family member E, Histone H2B type 2-E, Histone H2A.Z | | 著者 | Shan, S, Pan, L, Mao, Z, Wang, W, Sun, J, Dong, Q, Liang, X, Ding, X, Chen, S, Dai, L, Zhang, Z, Zhu, B, Zhou, Z. | | 登録日 | 2013-11-01 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Cell Res., 24, 2014
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8WNS
 | | Cryo EM map of SLC7A10 in the apo state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1 | | 著者 | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | 登録日 | 2023-10-06 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
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8WNY
 | | Cryo EM map of SLC7A10-SLC3A2 complex in the D-serine bound state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1, ... | | 著者 | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | 登録日 | 2023-10-06 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
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8WNT
 | | Cryo EM map of SLC7A10 with L-Alanine substrate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALANINE, ... | | 著者 | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | | 登録日 | 2023-10-06 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
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1WQE
 | | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis | | 分子名称: | OmTx3 | | 著者 | Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. | | 登録日 | 2004-09-28 | | 公開日 | 2005-01-18 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Biochem.J., 388, 2005
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1WQC
 | | An unusual fold for potassium channel blockers : NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis | | 分子名称: | OmTx1 | | 著者 | Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. | | 登録日 | 2004-09-27 | | 公開日 | 2005-01-18 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Biochem.J., 388, 2005
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1WQD
 | | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis | | 分子名称: | OmTx2 | | 著者 | Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. | | 登録日 | 2004-09-28 | | 公開日 | 2005-01-18 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Biochem.J., 388, 2005
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1WMT
 | | Scorpion toxin (IsTX) from Opisthacanthus madagascariensis | | 分子名称: | IsTX | | 著者 | Yamaji, N, Dai, L, Sugase, K, Andriantsiferana, M, Nakajima, T, Iwashita, T. | | 登録日 | 2004-07-20 | | 公開日 | 2004-10-19 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of IsTX: A male scorpion toxin from Opisthacanthus madagascariensis (Ischnuridae)
Eur.J.Biochem., 271, 2004
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