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4V7V
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BU of 4v7v by Molmil
Crystal structure of the E. coli ribosome bound to clindamycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
登録日2010-08-16
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.2891 Å)
主引用文献Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V9D
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BU of 4v9d by Molmil
Structures of the bacterial ribosome in classical and hybrid states of tRNA binding
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Wang, L, Feldman, M.B, Pulk, A, Chen, V.B, Kapral, G.J, Noeske, J, Richardson, J.S, Blanchard, S.C, Cate, J.H.D.
登録日2012-07-31
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of the bacterial ribosome in classical and hybrid states of tRNA binding.
Science, 332, 2011
4V54
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BU of 4v54 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome recycling factor (RRF).
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-16
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
4V57
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BU of 4v57 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D.
登録日2007-07-21
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
4V4Q
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BU of 4v4q by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D.
登録日2005-08-30
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structures of the bacterial ribosome at 3.5 A resolution.
Science, 310, 2005
4WWW
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BU of 4www by Molmil
Crystal structure of the E. coli ribosome bound to CEM-101
分子名称: (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S rRNA, 23S rRNA, ...
著者Dunkle, J.A, Zhang, W, Cate, J.H.D, Mankin, A.S.
登録日2014-11-12
公開日2014-12-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis.
Antimicrob. Agents Chemother., 54, 2010
4WOI
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BU of 4woi by Molmil
4,5-linked aminoglycoside antibiotics regulate the bacterial ribosome by targeting dynamic conformational processes within intersubunit bridge B2
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Pulk, A, Cate, J.H.D, Blanchard, S, Wasserman, M, Altman, R, Zhou, Z, Zinder, J, Green, K, Garneau-Tsodikova, S.
登録日2014-10-15
公開日2015-08-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.
Nat Commun, 6, 2015
4WF1
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BU of 4wf1 by Molmil
Crystal structure of the E. coli ribosome bound to negamycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C.
登録日2014-09-11
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4YBB
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BU of 4ybb by Molmil
High-resolution structure of the Escherichia coli ribosome
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
著者Noeske, J, Wasserman, M.R, Terry, D.S, Altman, R.B, Blanchard, S.C, Cate, J.H.D.
登録日2015-02-18
公開日2015-03-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High-resolution structure of the Escherichia coli ribosome.
Nat.Struct.Mol.Biol., 22, 2015
5K4C
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BU of 5k4c by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2
分子名称: Eukaryotic translation initiation factor 3 subunit D, GLYCEROL
著者Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
登録日2016-05-20
公開日2016-07-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
5K4B
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BU of 5k4b by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 1
分子名称: CHLORIDE ION, Eukaryotic translation initiation factor 3 subunit D
著者Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
登録日2016-05-20
公開日2016-07-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.399 Å)
主引用文献eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
5K4D
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BU of 5k4d by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 3
分子名称: Eukaryotic translation initiation factor 3 subunit D
著者Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
登録日2016-05-20
公開日2016-07-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
4EIR
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BU of 4eir by Molmil
Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases (PMO-2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, GLYCEROL, ...
著者Li, X, Beeson, W.T, Phillips, C.M, Marletta, M.A, Cate, J.H.
登録日2012-04-05
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases.
Structure, 20, 2012
4EIS
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BU of 4eis by Molmil
Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases (PMO-3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, PEROXIDE ION, ...
著者Li, X, Beeson, W.T, Phillips, C.M, Marletta, M.A, Cate, J.H.
登録日2012-04-05
公開日2012-05-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases.
Structure, 20, 2012
8EIU
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BU of 8eiu by Molmil
E. coli 70S ribosome with A-loop mutations U2554C and U2555C
分子名称: 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
著者Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D.
登録日2022-09-15
公開日2023-02-01
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.24 Å)
主引用文献Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic Acids Res., 51, 2023
8EMM
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BU of 8emm by Molmil
Composite 70S ribosome structure for "Atomistic simulations of the E. coli ribosome provide selection criteria for translationally active substrates
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Watson, Z.L, Cate, J.H.D.
登録日2022-09-28
公開日2023-05-31
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates.
Nat.Chem., 15, 2023
8FTO
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BU of 8fto by Molmil
E. coli 70S ribosome with an improved MS2 tag inserted in H98
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nissley, A.J, Cate, J.H.D.
登録日2023-01-12
公開日2023-08-02
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.85 Å)
主引用文献Interactions between terminal ribosomal RNA helices stabilize the E. coli large ribosomal subunit.
Rna, 29, 2023
8G6W
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BU of 8g6w by Molmil
Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
分子名称: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ...
著者Majumdar, C, Cate, J.H.D.
登録日2023-02-16
公開日2023-04-05
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.02 Å)
主引用文献Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8G6X
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BU of 8g6x by Molmil
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site meta-aminobenzoic acid charged NH-tRNAPhe
分子名称: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminobenzamide, ...
著者Majumdar, C, Cate, J.H.D.
登録日2023-02-16
公開日2023-03-22
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.31 Å)
主引用文献Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8G6Y
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BU of 8g6y by Molmil
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site 3-aminopyridine-4-carboxylic acid charged NH-tRNAPhe
分子名称: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminopyridine-4-carboxamide, ...
著者Majumdar, C, Cate, J.H.D.
登録日2023-02-16
公開日2023-04-05
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.09 Å)
主引用文献Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
6OM0
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BU of 6om0 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-17
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLE
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BU of 6ole by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM7
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BU of 6om7 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-18
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLZ
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BU of 6olz by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-17
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLG
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BU of 6olg by Molmil
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019

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