4XIB
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4XI6
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1D2J
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5HQG
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5IGO
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5IGQ
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5I6V
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5J45
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4TSE
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1IJQ
| Crystal Structure of the LDL Receptor YWTD-EGF Domain Pair | 分子名称: | LOW-DENSITY LIPOPROTEIN RECEPTOR | 著者 | Jeon, H, Meng, W, Takagi, J, Eck, M.J, Springer, T.A, Blacklow, S.C. | 登録日 | 2001-04-27 | 公開日 | 2001-05-23 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. Nat.Struct.Biol., 8, 2001
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4ZLP
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2OO4
| Structure of LNR-HD (Negative Regulatory Region) from human Notch 2 | 分子名称: | CALCIUM ION, GLYCEROL, Neurogenic locus notch homolog protein 2, ... | 著者 | Gordon, W.R, Vardar-Ulu, D, Histen, G, Sanchez-Irizarry, C, Aster, J.C, Blacklow, S.C. | 登録日 | 2007-01-25 | 公開日 | 2007-04-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Structural basis for autoinhibition of Notch Nat.Struct.Mol.Biol., 14, 2007
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1L3Y
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3I08
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1NU2
| Crystal structure of the murine Disabled-1 (Dab1) PTB domain-ApoER2 peptide-PI-4,5P2 ternary complex | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Disabled homolog 1, peptide derived from murine Apolipoprotein E Receptor-2 | 著者 | Stolt, P.C, Jeon, H, Song, H.K, Herz, J, Eck, M.J, Blacklow, S.C. | 登録日 | 2003-01-30 | 公開日 | 2003-04-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Origins of Peptide Selectivity and Phosphoinositide Binding Revealed by Structures of Disabled-1 PTB Domain Complexes Structure, 11, 2003
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2F8X
| Crystal structure of activated Notch, CSL and MAML on HES-1 promoter DNA sequence | 分子名称: | 5'-D(*GP*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*AP*AP*A)-3', 5'-D(*TP*TP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*TP*AP*AP*C)-3', Mastermind-like protein 1, ... | 著者 | Nam, Y, Sliz, P, Blacklow, S.C. | 登録日 | 2005-12-04 | 公開日 | 2006-04-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell(Cambridge,Mass.), 124, 2006
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2FCW
| Structure of a Complex Between the Pair of the LDL Receptor Ligand-Binding Modules 3-4 and the Receptor Associated Protein (RAP). | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-2-macroglobulin receptor-associated protein, CALCIUM ION, ... | 著者 | Beglova, N, Fisher, C, Blacklow, S.C. | 登録日 | 2005-12-12 | 公開日 | 2006-05-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Structure of an LDLR-RAP Complex Reveals a General Mode for Ligand Recognition by Lipoprotein Receptors Mol.Cell, 22, 2006
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2F8Y
| Crystal structure of human Notch1 ankyrin repeats to 1.55A resolution. | 分子名称: | Notch homolog 1, translocation-associated (Drosophila), SULFATE ION | 著者 | Nam, Y, Sliz, P, Blacklow, S.C. | 登録日 | 2005-12-04 | 公開日 | 2006-04-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell(Cambridge,Mass.), 124, 2006
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1XFE
| Solution structure of the LA7-EGFA pair from the LDL receptor | 分子名称: | CALCIUM ION, Low-density lipoprotein receptor | 著者 | Beglova, N, Jeon, H, Fisher, C, Blacklow, S.C. | 登録日 | 2004-09-14 | 公開日 | 2004-11-02 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Cooperation between Fixed and Low pH-Inducible Interfaces Controls Lipoprotein Release by the LDL Receptor Mol.Cell, 16, 2004
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5VO5
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5WA5
| Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor XMD11-50 | 分子名称: | 1,2-ETHANEDIOL, 2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Bromodomain-containing protein 4 | 著者 | Xu, X, Blacklow, S.C. | 登録日 | 2017-06-24 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.172 Å) | 主引用文献 | Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains. ACS Chem. Biol., 13, 2018
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5W55
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5VNY
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1PB5
| NMR Structure of a Prototype LNR Module from Human Notch1 | 分子名称: | CALCIUM ION, Neurogenic locus notch homolog protein 1 | 著者 | Vardar, D, North, C.L, Sanchez-Irizarry, C, Aster, J.C, Blacklow, S.C. | 登録日 | 2003-05-14 | 公開日 | 2003-06-17 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear Magnetic Resonance Structure of a Prototype Lin12-Notch Repeat Module from Human Notch1 Biochemistry, 42, 2003
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1NTV
| Crystal Structure of the Disabled-1 (Dab1) PTB domain-ApoER2 peptide complex | 分子名称: | Apolipoprotein E Receptor-2 peptide, Disabled homolog 1, PHOSPHATE ION | 著者 | Stolt, P.C, Jeon, H, Song, H.K, Herz, J, Eck, M.J, Blacklow, S.C. | 登録日 | 2003-01-30 | 公開日 | 2003-04-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Origins of Peptide Selectivity and Phosphoinositide Binding Revealed by Structures of Disabled-1 PTB Domain Complexes Structure, 11, 2003
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