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4ZLP

Crystal Structure of Notch3 Negative Regulatory Region

Summary for 4ZLP
Entry DOI10.2210/pdb4zlp/pdb
DescriptorNeurogenic locus notch homolog protein 3, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total)
Functional Keywordsnotch, mutation, disease, autoinhibiton, transcription
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight61797.97
Authors
Xu, X.,Blacklow, S.C. (deposition date: 2015-05-01, release date: 2015-08-19, Last modification date: 2020-07-29)
Primary citationXu, X.,Choi, S.H.,Hu, T.,Tiyanont, K.,Habets, R.,Groot, A.J.,Vooijs, M.,Aster, J.C.,Chopra, R.,Fryer, C.,Blacklow, S.C.
Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region.
Structure, 23:1227-1235, 2015
Cited by
PubMed: 26051713
DOI: 10.1016/j.str.2015.05.001
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.479 Å)
Structure validation

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