4ZLP
Crystal Structure of Notch3 Negative Regulatory Region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neurogenic locus notch homolog protein 3 | polymer | 271 | 30096.6 | 2 | UniProt (Q9UM47) Pfam (PF00066) Pfam (PF06816) Pfam (PF07684) | Homo sapiens (Human) | Notch 3 |
| 2 | C (C) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G04854NQ) | |||
| 3 | D, E, F, K, L... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | G, H, O (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | I, J (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 6 | N (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | P, Q (A, B) | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A, B: 1378 - 1640 (UniProt: Q9UM47)
| PDB | External Database | Details |
|---|---|---|
| Gly 1641 | - | expression tag |
| Ser 1642 | - | expression tag |
| His 1643 | - | expression tag |
| His 1644 | - | expression tag |
| His 1645 | - | expression tag |
| His 1646 | - | expression tag |
| His 1647 | - | expression tag |
| His 1648 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60193.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 856.0 | |
| All* | Total formula weight | 61798.0 |
