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4ZLP

Crystal Structure of Notch3 Negative Regulatory Region

Functional Information from GO Data
ChainGOidnamespacecontents
A0006355biological_processregulation of DNA-templated transcription
A0007219biological_processNotch signaling pathway
A0007275biological_processmulticellular organism development
A0016020cellular_componentmembrane
A0030154biological_processcell differentiation
A0038023molecular_functionsignaling receptor activity
B0006355biological_processregulation of DNA-templated transcription
B0007219biological_processNotch signaling pathway
B0007275biological_processmulticellular organism development
B0016020cellular_componentmembrane
B0030154biological_processcell differentiation
B0038023molecular_functionsignaling receptor activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Cleavage; by furin-like protease => ECO:0000250
ChainResidueDetails
AARG1571
BARG1571

site_idSWS_FT_FI2
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN1438
BASN1438

237423

PDB entries from 2025-06-11

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