2KO3
 
 | | Nedd8 solution structure | | 分子名称: | NEDD8 | | 著者 | Choi, Y.S, Jeon, Y.H, Cheong, C. | | 登録日 | 2009-09-09 | | 公開日 | 2009-11-03 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 60th residues of ubiquitin and Nedd8 are located out of E2-binding surfaces, but are important for K48 ubiquitin-linkage.
Febs Lett., 583, 2009
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2KLO
 | | Structure of the Cdt1 C-terminal domain | | 分子名称: | DNA replication factor Cdt1 | | 著者 | Khayrutdinov, B.I, Bae, W.J, Yun, Y.M, Tsuyama, T, Kim, J.J, Hwang, E, Ryu, K.-S, Cheong, H.-K, Cheong, C, Karplus, P.A, Guntert, P, Tada, S, Jeon, Y.H, Cho, Y. | | 登録日 | 2009-07-06 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors
Protein Sci., 18, 2009
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3NQW
 | | A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses | | 分子名称: | CG11900, MANGANESE (II) ION, SULFATE ION | | 著者 | Sun, D.W, Kim, H.Y, Kim, K.J, Jeon, Y.H, Chung, J. | | 登録日 | 2010-06-30 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses
Nat.Struct.Mol.Biol., 17, 2010
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3NR1
 | | A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses | | 分子名称: | HD domain-containing protein 3, MANGANESE (II) ION | | 著者 | Sun, D.W, Kim, H.Y, Kim, K.J, Jeon, Y.H, Chung, J. | | 登録日 | 2010-06-30 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses
Nat.Struct.Mol.Biol., 17, 2010
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4OH9
 | | Crystal Structure of the human MST2 SARAH homodimer | | 分子名称: | Serine/threonine-protein kinase 3 | | 著者 | Hwang, E, Cheong, H.-K, Ul Mushtaq, A, Kim, H.-Y, Yeo, K.J, Kim, E, Lee, W.C, Hwang, K.Y, Cheong, C, Jeon, Y.H. | | 登録日 | 2014-01-17 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | Structural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathway.
Acta Crystallogr.,Sect.D, 70, 2014
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4OH8
 | | Crystal Structure of the human MST1-RASSF5 SARAH heterodimer | | 分子名称: | Ras association domain-containing protein 5, Serine/threonine-protein kinase 4 | | 著者 | Hwang, E, Cheong, H.-K, Ul Mushtaq, A, Kim, H.-Y, Yeo, K.J, Kim, E, Lee, W.C, Hwang, K.Y, Cheong, C, Jeon, Y.H. | | 登録日 | 2014-01-17 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.281 Å) | | 主引用文献 | Structural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathway.
Acta Crystallogr.,Sect.D, 70, 2014
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3RFS
 | | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering | | 分子名称: | Internalin B, repeat modules, Variable lymphocyte receptor B, ... | | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | | 登録日 | 2011-04-06 | | 公開日 | 2012-03-14 | | 最終更新日 | 2017-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering
Proc.Natl.Acad.Sci.USA, 109, 2012
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3RFJ
 | | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering | | 分子名称: | Internalin B, repeat modules, Variable lymphocyte receptor, ... | | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | | 登録日 | 2011-04-06 | | 公開日 | 2012-03-14 | | 最終更新日 | 2017-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering
Proc.Natl.Acad.Sci.USA, 109, 2012
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3UL8
 | | Crystal structure of the TV3 mutant V134L | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ... | | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | | 登録日 | 2011-11-10 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
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3UL7
 | | Crystal structure of the TV3 mutant F63W | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ... | | 著者 | Kim, H.J, Cheong, H.K, Jeon, Y.H. | | 登録日 | 2011-11-10 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
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5XGA
 | | Crystal structure of the EnvZ periplasmic domain with CHAPS | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ACETIC ACID, Osmolarity sensor protein EnvZ | | 著者 | Hwang, E, Cheong, H.K, Jeon, Y.H, Cheong, C. | | 登録日 | 2017-04-13 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | | 主引用文献 | Crystal structure of the EnvZ periplasmic domain with CHAPS.
FEBS Lett., 591, 2017
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5YSO
 | | Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domain with DN200434 | | 分子名称: | 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma | | 著者 | Cho, S.J, Chin, J.W, Yoon, H.S, Jeon, Y.H, Bae, J.H, Song, J.Y. | | 登録日 | 2017-11-14 | | 公開日 | 2018-12-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERR gamma ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
Clin.Cancer Res., 25, 2019
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4K87
 | | Crystal structure of human prolyl-tRNA synthetase (substrate bound form) | | 分子名称: | ADENOSINE, PROLINE, Proline--tRNA ligase, ... | | 著者 | Hwang, K.Y, Son, J.H, Lee, E.H. | | 登録日 | 2013-04-18 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
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3GWJ
 | | Crystal structure of Antheraea pernyi arylphorin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Arylphorin, FORMIC ACID, ... | | 著者 | Ryu, K.S, Lee, J.O, Kwon, T.H, Kim, S. | | 登録日 | 2009-04-01 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | The presence of monoglucosylated N196-glycan is important for the structural stability of storage protein, arylphorin
Biochem.J., 421, 2009
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6A6K
 | | Crystal structure of Estrogen-related Receptor-3 (ERR-gamma) ligand binding domain with DN201000 | | 分子名称: | 3-[(~{E})-5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma | | 著者 | Yoon, H, Kim, J, Chin, J, Cho, S.J, Song, J. | | 登録日 | 2018-06-28 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-gamma Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.
J. Med. Chem., 62, 2019
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6KNR
 | | Crystal structure of Estrogen-related receptor gamma ligand-binding domain with DN200699 | | 分子名称: | (E)-4-(1-(4-(1-cyclopropylpiperidin-4-yl)phenyl)-5-hydroxy-2-phenylpent-1-en-1-yl)phenol, Estrogen-related receptor gamma | | 著者 | Yoon, H, Kim, J, Chin, J, Song, J, Cho, S.J. | | 登録日 | 2019-08-07 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | | 主引用文献 | An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.
Eur.J.Med.Chem., 205, 2020
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2XXN
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2HQR
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2HQN
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2HQO
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2KCC
 | | Solution Structure of biotinoyl domain from human acetyl-CoA carboxylase 2 | | 分子名称: | Acetyl-CoA carboxylase 2 | | 著者 | Lee, C, Cheong, H, Ryu, K, Lee, J, Lee, W, Jeon, Y, Cheong, C. | | 登録日 | 2008-12-19 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Biotinoyl domain of human acetyl-CoA carboxylase: Structural insights into the carboxyl transfer mechanism.
Proteins, 72, 2008
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2KSD
 | | Backbone structure of the membrane domain of E. coli histidine kinase receptor ArcB, Center for Structures of Membrane Proteins (CSMP) target 4310C | | 分子名称: | Aerobic respiration control sensor protein arcB | | 著者 | Maslennikov, I, Klammt, C, Hwang, E, Kefala, G, Kwiatkowski, W, Jeon, Y, Choe, S, Center for Structures of Membrane Proteins (CSMP) | | 登録日 | 2010-01-02 | | 公開日 | 2010-03-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3IKW
 | | Structure of Heparinase I from Bacteroides thetaiotaomicron | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Heparin lyase I | | 著者 | Garron, M.L, Cygler, M, Shaya, D. | | 登録日 | 2009-08-06 | | 公開日 | 2009-09-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural snapshots of heparin depolymerization by heparin lyase I.
J.Biol.Chem., 284, 2009
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3ILR
 | | Structure of Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product | | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(4-1)-4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid, 4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ... | | 著者 | Garron, M.L, Cygler, M, Shaya, D. | | 登録日 | 2009-08-07 | | 公開日 | 2009-09-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural snapshots of heparin depolymerization by heparin lyase I.
J.Biol.Chem., 284, 2009
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4LL1
 | | The structure of the TRX and TXNIP complex | | 分子名称: | Thioredoxin, Thioredoxin-interacting protein | | 著者 | Hwang, J, Kim, M.H. | | 登録日 | 2013-07-09 | | 公開日 | 2014-02-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
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