4OH8

Crystal Structure of the human MST1-RASSF5 SARAH heterodimer

Summary for 4OH8

Related4OH9
DescriptorSerine/threonine-protein kinase 4, Ras association domain-containing protein 5 (3 entities in total)
Functional Keywordscoiled-coil, sarah domain, homodimerization, heterodomerization, transferase-apoptosis complex, transferase/apoptosis
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q13043 Q8WWW0
Total number of polymer chains2
Total molecular weight12639.23
Authors
Primary citation
Hwang, E.,Cheong, H.K.,Mushtaq, A.U.,Kim, H.Y.,Yeo, K.J.,Kim, E.,Lee, W.C.,Hwang, K.Y.,Cheong, C.,Jeon, Y.H.
Structural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathway.
Acta Crystallogr.,Sect.D, 70:1944-1953, 2014
PubMed: 25004971 (PDB entries with the same primary citation)
DOI: 10.1107/S139900471400947X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.281 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.27830 2.4% 1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
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PDB entries from 2020-12-02