4OH9

Crystal Structure of the human MST2 SARAH homodimer

Summary for 4OH9

Entry DOI	10.2210/pdb4oh9/pdb
Related	4OH8
Descriptor	Serine/threonine-protein kinase 3 (2 entities in total)
Functional Keywords	sarah domain, coiled-coil, homodierizarion, heterodimerization, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm (By similarity): Q13188
Total number of polymer chains	2
Total formula weight	12188.09
Authors	Hwang, E.,Cheong, H.-K.,Ul Mushtaq, A.,Kim, H.-Y.,Yeo, K.J.,Kim, E.,Lee, W.C.,Hwang, K.Y.,Cheong, C.,Jeon, Y.H. (deposition date: 2014-01-17, release date: 2014-07-23, Last modification date: 2023-09-20)
Primary citation	Hwang, E.,Cheong, H.K.,Mushtaq, A.U.,Kim, H.Y.,Yeo, K.J.,Kim, E.,Lee, W.C.,Hwang, K.Y.,Cheong, C.,Jeon, Y.H. Structural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathway. Acta Crystallogr.,Sect.D, 70:1944-1953, 2014 Cited by PubMed: 25004971 DOI: 10.1107/S139900471400947X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.699 Å)

Structure validation