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6O30
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Lipid A transporter MsbA from Salmonella typhimurium
分子名称: Lipid A export ATP-binding/permease protein MsbA
著者Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L.
登録日2019-02-25
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.47 Å)
主引用文献Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
6O3L
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BU of 6o3l by Molmil
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41).
分子名称: GLYCEROL, MPER peptide, region 671-683 of HIV-1 gp41, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-26
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O41
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Crystal structure of the unbound PGZL1 germline Fab fragment (PGZL1_gVmDmJ)
分子名称: GLYCEROL, Immunoglobulin G-binding protein G (DOMAIN III), germline PGZL1_gVmDmJ heavy chain, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-27
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.465 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6N32
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BU of 6n32 by Molmil
Anti-HIV-1 Fab 2G12 re-refinement
分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, SULFATE ION
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-11-14
公開日2018-11-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science, 300, 2003
6NHP
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BU of 6nhp by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA2 I45T mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2018-12-23
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.
Science, 368, 2020
6ME1
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BU of 6me1 by Molmil
Crystal structure of the clade B isolate B41 mutant fusion peptide (residues 512-521) in complex with VRC34.01
分子名称: Envelope glycoprotein gp160, VRC34.01 Fab heavy chain, VRC34.01 Fab light chain
著者Kumar, S, Sarkar, A, Wilson, I.A.
登録日2018-09-05
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
6N35
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BU of 6n35 by Molmil
Anti-HIV-1 Fab 2G12 + Man1-2 re-refinement
分子名称: BENZOIC ACID, Fab 2G12 heavy chain, Fab 2G12 light chain, ...
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-11-14
公開日2018-11-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.747 Å)
主引用文献Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science, 300, 2003
6OO0
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BU of 6oo0 by Molmil
Crystal structure of bovine Fab NC-Cow1
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, NC-Cow1 heavy chain, NC-Cow1 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2019-04-22
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
6O3U
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BU of 6o3u by Molmil
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, GLYCEROL, PGZL1.H4K3 heavy chain, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-27
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.105 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
4FI7
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BU of 4fi7 by Molmil
Kinetic Stabilization of transthyretin through covalent modification of K15 by 3-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide
分子名称: 3-[5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]benzenesulfonyl fluoride, Transthyretin
著者Connelly, S, Grimster, N, Wilson, I.A, Kelly, J.W.
登録日2012-06-08
公開日2013-02-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate.
J.Am.Chem.Soc., 135, 2013
4FQJ
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BU of 4fqj by Molmil
Influenza B/Florida/4/2006 hemagglutinin Fab CR8071 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, antibody CR8071 heavy chain, ...
著者Dreyfus, C, Laursen, N.S, Wilson, I.A.
登録日2012-06-25
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Highly conserved protective epitopes on influenza B viruses.
Science, 337, 2012
4FQY
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BU of 4fqy by Molmil
Crystal structure of broadly neutralizing antibody CR9114 bound to H3 influenza hemagglutinin
分子名称: Antibody CR9114 heavy chain, Antibody CR9114 light chain, Hemagglutinin HA1, ...
著者Ekiert, D.C, Dreyfus, C, Wilson, I.A.
登録日2012-06-25
公開日2012-08-22
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (5.253 Å)
主引用文献Highly conserved protective epitopes on influenza B viruses.
Science, 337, 2012
4FP8
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BU of 4fp8 by Molmil
Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin, HA1 subunit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05, ...
著者Ekiert, D.C, Wilson, I.A.
登録日2012-06-21
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.947 Å)
主引用文献Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
4FQI
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Crystal Structure of Fab CR9114 in Complex with a H5N1 influenza virus hemagglutinin
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dreyfus, C, Wilson, I.A.
登録日2012-06-25
公開日2012-08-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Highly conserved protective epitopes on influenza B viruses.
Science, 337, 2012
4GMS
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BU of 4gms by Molmil
Crystal structure of heterosubtypic Fab S139/1 in complex with influenza A H3 hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab S139/1 heavy chain, ...
著者Lee, P.S, Ekiert, D.C, Wilson, I.A.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GDI
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A subtype N10 neuraminidase-like protein of A/little yellow-shouldered bat/Guatemala/164/2009
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhu, X, Wilson, I.A.
登録日2012-07-31
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site.
Proc.Natl.Acad.Sci.USA, 109, 2012
4G6A
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BU of 4g6a by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody AP33
分子名称: AP33 Heavy Chain, AP33 Light chain, E2 peptide
著者Kong, L, Wilson, I.A, Law, M.
登録日2012-07-18
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33.
J.Virol., 86, 2012
4GMT
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BU of 4gmt by Molmil
Crystal structure of heterosubtypic Fab S139/1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab S139/1 heavy chain, ...
著者Lee, P.S, Ekiert, D.C, Wilson, I.A.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GDJ
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A subtype N10 neuraminidase-like protein of A/little yellow-shouldered bat/Guatemala/060/2010
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ...
著者Zhu, X, Wilson, I.A.
登録日2012-07-31
公開日2012-09-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GHA
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BU of 4gha by Molmil
Crystal structure of Marburg virus VP35 RNA binding domain bound to 12-bp dsRNA
分子名称: Polymerase cofactor VP35, RNA (5'-R(*CP*UP*AP*GP*AP*CP*GP*UP*CP*UP*AP*G)-3')
著者Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O.
登録日2012-08-07
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism.
Plos Pathog., 8, 2012
4GH9
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Crystal structure of Marburg virus VP35 RNA binding domain
分子名称: ACETATE ION, Polymerase cofactor VP35
著者Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O.
登録日2012-08-07
公開日2012-08-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism.
Plos Pathog., 8, 2012
4HFU
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BU of 4hfu by Molmil
Crystal structure of Fab 8M2 in complex with a H2N2 influenza virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 8M2 heavy chain, Fab 8M2 light chain, ...
著者Xu, R, Wilson, I.A.
登録日2012-10-05
公開日2013-02-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin.
Nat.Struct.Mol.Biol., 20, 2013
4GXU
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Crystal structure of antibody 1F1 bound to the 1918 influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1F1, heavy chain, ...
著者Ekiert, D.C, Wilson, I.A.
登録日2012-09-04
公開日2012-12-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.294 Å)
主引用文献Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses.
Plos Pathog., 8, 2012
4GZQ
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N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with sialic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, N-acetyl-alpha-neuraminic acid, ...
著者Zhu, X, Wilson, I.A.
登録日2012-09-06
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.
J.Virol., 86, 2012
4GZT
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N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with oseltamivir carboxylate
分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2012-09-06
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.
J.Virol., 86, 2012

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