7PFN
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7PEH
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![BU of 7peh by Molmil](/molmil-images/mine/7peh) | Crystal Structure of a Class D Carbapenemase | 分子名称: | 1-BUTANOL, Beta-lactamase | 著者 | Zhou, Q, He, Y, Jin, Y. | 登録日 | 2021-08-10 | 公開日 | 2022-08-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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7PEI
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7PEP
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![BU of 7pep by Molmil](/molmil-images/mine/7pep) | Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem | 分子名称: | (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid, 1-BUTANOL, BROMIDE ION, ... | 著者 | Zhou, Q, He, Y, Jin, Y. | 登録日 | 2021-08-11 | 公開日 | 2022-08-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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7PSF
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7PSE
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![BU of 7pse by Molmil](/molmil-images/mine/7pse) | Crystal Structure of a Class D Carbapenemase_K73ALY Complexed with Oxacillin | 分子名称: | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, 1-BUTANOL, Beta-lactamase, ... | 著者 | Zhou, Q, He, Y, Jin, Y. | 登録日 | 2021-09-23 | 公開日 | 2022-10-05 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity Acs Cent.Sci., 2023
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7Q14
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8QNZ
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![BU of 8qnz by Molmil](/molmil-images/mine/8qnz) | Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem | 分子名称: | (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, 1-BUTANOL, BROMIDE ION, ... | 著者 | Zhou, Q, He, Y, Jin, Y. | 登録日 | 2023-09-27 | 公開日 | 2023-11-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity. Acs Cent.Sci., 9, 2023
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1NMF
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1NMG
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5CKA
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![BU of 5cka by Molmil](/molmil-images/mine/5cka) | Human beta-2 microglobulin double mutant W60G-N83V | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | 登録日 | 2015-07-15 | 公開日 | 2016-05-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability. Sci Rep, 6, 2016
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5CKG
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![BU of 5ckg by Molmil](/molmil-images/mine/5ckg) | Human beta-2 microglobulin mutant V85E | 分子名称: | ACETATE ION, Beta-2-microglobulin, GLYCEROL | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | 登録日 | 2015-07-15 | 公開日 | 2016-05-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability. Sci Rep, 6, 2016
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5CFH
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4ISY
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![BU of 4isy by Molmil](/molmil-images/mine/4isy) | |
5CSG
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5CSB
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![BU of 5csb by Molmil](/molmil-images/mine/5csb) | The crystal structure of beta2-microglobulin D76N mutant at room temperature | 分子名称: | Beta-2-microglobulin | 著者 | de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S. | 登録日 | 2015-07-23 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.719 Å) | 主引用文献 | Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity. Nat Commun, 9, 2018
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7PUX
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8Q1K
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![BU of 8q1k by Molmil](/molmil-images/mine/8q1k) | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | 著者 | Roske, Y, Daumke, O, Damme, M. | 登録日 | 2023-07-31 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation. Nucleic Acids Res., 52, 2024
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8Q1X
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![BU of 8q1x by Molmil](/molmil-images/mine/8q1x) | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | 著者 | Roske, Y, Daumke, O, Damme, M. | 登録日 | 2023-08-01 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation. Nucleic Acids Res., 52, 2024
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5CS7
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![BU of 5cs7 by Molmil](/molmil-images/mine/5cs7) | The crystal structure of wt beta2-microglobulin at room temperature | 分子名称: | Beta-2-microglobulin | 著者 | de Rosa, M, Mota, C.S, de Sanctis, D, Bolognesi, M, Ricagno, S. | 登録日 | 2015-07-23 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity. Nat Commun, 9, 2018
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4LDD
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4LDM
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5WHR
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![BU of 5whr by Molmil](/molmil-images/mine/5whr) | Discovery of a novel and selective IDO-1 inhibitor PF-06840003 and its characterization as a potential clinical candidate. | 分子名称: | (3R)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Greasley, S.E, Kaiser, S.E, Feng, J.L, Stewart, A. | 登録日 | 2017-07-18 | 公開日 | 2017-12-27 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate. J. Med. Chem., 60, 2017
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4LDI
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4LDB
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