5KE9
| |
5KEA
| |
5KL6
| Wilms Tumor Protein (WT1) Q369R ZnF2-4 in complex with DNA | 分子名称: | DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*CP*CP*CP*AP*CP*GP*C)-3'), Wilms tumor protein, ... | 著者 | Hashimoto, H, Cheng, X. | 登録日 | 2016-06-23 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | 主引用文献 | Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res., 44, 2016
|
|
5KL4
| |
5KKQ
| Homo sapiens CCCTC-binding factor (CTCF) ZnF3-7 and DNA complex structure | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), Transcriptional repressor CTCF, ... | 著者 | Hashimoto, H, Wang, D, Cheng, X. | 登録日 | 2016-06-22 | 公開日 | 2017-05-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.744 Å) | 主引用文献 | Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
|
|
5KL5
| Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with carboxylated DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | 著者 | Hashimoto, H, Cheng, X. | 登録日 | 2016-06-23 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.289 Å) | 主引用文献 | Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res., 44, 2016
|
|
5KL2
| Wilms Tumor Protein (WT1) ZnF2-4 in complex with DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*AP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), ... | 著者 | Hashimoto, H, Cheng, X. | 登録日 | 2016-06-23 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.692 Å) | 主引用文献 | Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res., 44, 2016
|
|
7VKM
| Crystal structure of TrkA (G595R) kinase domain | 分子名称: | Tyrosine-protein kinase receptor | 著者 | Murray, B.W, Rogers, E, Zhai, D, Deng, W, Chen, X, Sprengeler, P.A, Zhang, X, Graber, A, Reich, S.H, Stopatschinskaja, S, Solomon, B, Besse, B, Drilon, A. | 登録日 | 2021-09-30 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Molecular Characteristics of Repotrectinib That Enable Potent Inhibition of TRK Fusion Proteins and Resistant Mutations. Mol.Cancer Ther., 20, 2021
|
|
7VKO
| Crystal structure of TrkA kinase with repotrectinib | 分子名称: | Repotrectinib, SULFATE ION, Tyrosine-protein kinase receptor | 著者 | Murray, B.W, Rogers, E, Zhai, D, Deng, W, Chen, X, Sprengeler, P.A, Zhang, X, Graber, A, Reich, S.H, Stopatschinskaja, S, Solomon, B, Besse, B, Drilon, A. | 登録日 | 2021-09-30 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Molecular Characteristics of Repotrectinib That Enable Potent Inhibition of TRK Fusion Proteins and Resistant Mutations. Mol.Cancer Ther., 20, 2021
|
|
7VKN
| Crystal structure of TrkA (G595R) kinase with repotrectinib | 分子名称: | Repotrectinib, SULFATE ION, Tyrosine-protein kinase receptor | 著者 | Murray, B.W, Rogers, E, Zhai, D, Deng, W, Chen, X, Sprengeler, P.A, Zhang, X, Graber, A, Reich, S.H, Stopatschinskaja, S, Solomon, B, Besse, B, Drilon, A. | 登録日 | 2021-09-30 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular Characteristics of Repotrectinib That Enable Potent Inhibition of TRK Fusion Proteins and Resistant Mutations. Mol.Cancer Ther., 20, 2021
|
|
5Z9X
| Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 in complex with an RNA substrate | 分子名称: | MAGNESIUM ION, RNA (5'-R(P*GP*CP*CP*CP*AP*UP*UP*AP*G)-3'), SULFATE ION, ... | 著者 | Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Gan, J, Cao, C, Huang, Y, Chen, X, Ma, J. | 登録日 | 2018-02-05 | 公開日 | 2018-06-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1. Nat Commun, 9, 2018
|
|
5Z9Z
| The C-terminal RRM domain of Arabidopsis SMALL RNA DEGRADING NUCLEASE 1 (E329A/E330A/E332A) | 分子名称: | CITRATE ANION, Small RNA degrading nuclease 1 | 著者 | Chen, J, Liu, L, You, C, Gu, J, Ruan, W, Zhang, L, Cao, C, Gan, J, Huang, Y, Chen, X, Ma, J. | 登録日 | 2018-02-05 | 公開日 | 2018-06-27 | 最終更新日 | 2018-10-03 | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | 主引用文献 | Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1. Nat Commun, 9, 2018
|
|
6IZJ
| Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus | 分子名称: | 1,2-ETHANEDIOL, NITRATE ION, NreA | 著者 | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | 登録日 | 2018-12-19 | 公開日 | 2020-01-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus. Biotechnol.Lett., 42, 2020
|
|
6K2H
| structural characterization of mutated NreA protein in nitrate binding site from staphylococcus aureus. | 分子名称: | 1,2-ETHANEDIOL, NreA | 著者 | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | 登録日 | 2019-05-14 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus. Biotechnol.Lett., 42, 2020
|
|
8JQK
| Crystal structure of a carbonyl reductase SSCR mutant from Sporobolomyces Salmonicolor | 分子名称: | Aldehyde reductase 2 | 著者 | Zhang, H.L, Li, Q, Liu, W.D, Chen, X, Wu, Q.Q, Zhu, D.M. | 登録日 | 2023-06-14 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Engineering a Carbonyl Reductase to Simultaneously Increase Activity Toward Bulky Ketone and Isopropanol for Dynamic Kinetic Asymmetric Reduction via Enzymatic Hydrogen Transfer Acs Catalysis, 13, 2023
|
|
8JQJ
| Crystal structure of carbonyl reductase SSCR mutant 1 from Sporobolomyces Salmonicolor | 分子名称: | Aldehyde reductase 2 | 著者 | Zhang, H.L, Li, Q, Liu, W.D, Chen, X, Wu, Q.Q, Zhu, D.M. | 登録日 | 2023-06-14 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Engineering a Carbonyl Reductase to Simultaneously Increase Activity Toward Bulky Ketone and Isopropanol for Dynamic Kinetic Asymmetric Reduction via Enzymatic Hydrogen Transfer Acs Catalysis, 13, 2023
|
|
6JPJ
| Crystal structure of FGF401 in complex of FGFR4 | 分子名称: | Fibroblast growth factor receptor 4, N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide, SULFATE ION | 著者 | Zhou, Z, Chen, X, Chen, Y. | 登録日 | 2019-03-27 | 公開日 | 2019-05-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.638 Å) | 主引用文献 | Characterization of FGF401 as a reversible covalent inhibitor of fibroblast growth factor receptor 4. Chem.Commun.(Camb.), 55, 2019
|
|
8H8Y
| Crystal structure of AbHheG from Acidimicrobiia bacterium | 分子名称: | GLYCEROL, alpha/beta hydrolase | 著者 | Zhou, C.H, Chen, X, Han, X, Liu, W.D, Wu, Q.Q, Zhu, D.M, Ma, Y.H. | 登録日 | 2022-10-24 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides Acs Catalysis, 13, 2023
|
|
8HQP
| Crystal structure of AbHheG mutant from Acidimicrobiia bacterium | 分子名称: | AbHheG_m | 著者 | Zhou, C.H, Chen, X, Han, X, Liu, W.D, Wu, Q.Q, Zhu, D.M, Ma, Y.H. | 登録日 | 2022-12-13 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides Acs Catalysis, 13, 2023
|
|
7VI6
| Crystal structure of GH3 beta-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila | 分子名称: | Beta-N-acetylhexosaminidase, CHLORIDE ION, MAGNESIUM ION | 著者 | Qian, K, Yang, W, Chen, X, Wang, Y, Zhang, M, Wang, M. | 登録日 | 2021-09-26 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Functional and structural characterization of a GH3 beta-N-acetylhexosaminidase from Akkermansia muciniphila involved in mucin degradation Biochem.Biophys.Res.Commun., 589, 2022
|
|
7VI7
| Crystal structure of GH3 beta-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila in complex with GlcNAc | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ... | 著者 | Qian, K, Yang, W, Chen, X, Wang, Y, Zhang, M, Wang, M. | 登録日 | 2021-09-26 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Functional and structural characterization of a GH3 beta-N-acetylhexosaminidase from Akkermansia muciniphila involved in mucin degradation Biochem.Biophys.Res.Commun., 589, 2022
|
|
5ZE2
| Hairpin Complex, RAG1/2-hairpin 12RSS/23RSS complex in 5mM Mn2+ for 2 min at 4'C | 分子名称: | 1,2-ETHANEDIOL, DNA (30-MER), DNA (31-MER), ... | 著者 | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | 登録日 | 2018-02-25 | 公開日 | 2018-04-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
|
|
5ZDZ
| Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in Ca2+ | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, DNA (30-MER), ... | 著者 | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | 登録日 | 2018-02-25 | 公開日 | 2018-04-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
|
|
5ZE0
| Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+ | 分子名称: | 1,2-ETHANEDIOL, DNA (30-MER), DNA (39-MER), ... | 著者 | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | 登録日 | 2018-02-25 | 公開日 | 2018-04-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
|
|
5ZE1
| Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in 2mM Mn2+ for 10 min at 4'C | 分子名称: | 1,2-ETHANEDIOL, DNA, HMGB1 A-B box, ... | 著者 | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | 登録日 | 2018-02-25 | 公開日 | 2018-04-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
|
|