5KKQ

Homo sapiens CCCTC-binding factor (CTCF) ZnF3-7 and DNA complex structure

Summary for 5KKQ

• Entry DOI: 10.2210/pdb5kkq/pdb
• Descriptor: Transcriptional repressor CTCF, DNA (5'-D(*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*A)-3'), ... (5 entities in total)
• Functional Keywords: ctcf, zinc finger, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 56574.12

Authors

Hashimoto, H.,Wang, D.,Cheng, X. (deposition date: 2016-06-22, release date: 2017-05-24, Last modification date: 2024-03-06)

• Primary citation: Hashimoto, H.,Wang, D.,Horton, J.R.,Zhang, X.,Corces, V.G.,Cheng, X.; Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.; Mol. Cell, 66:711-720.e3, 2017; PubMed: 28529057; DOI: 10.1016/j.molcel.2017.05.004

Experimental method

X-RAY DIFFRACTION (1.744 Å)