8JQK

Crystal structure of a carbonyl reductase SSCR mutant from Sporobolomyces Salmonicolor

Summary for 8JQK

• Entry DOI: 10.2210/pdb8jqk/pdb
• Descriptor: Aldehyde reductase 2 (2 entities in total)
• Functional Keywords: sscr, reductase, carbonyl reductase, oxidoreductase
• Biological source: Sporobolomyces salmonicolor (Sporobolomyces salmonicolor)
• Total number of polymer chains: 2
• Total formula weight: 75173.26

Authors

Zhang, H.L.,Li, Q.,Liu, W.D.,Chen, X.,Wu, Q.Q.,Zhu, D.M. (deposition date: 2023-06-14, release date: 2023-12-27)

• Primary citation: Zhang, H.,Chen, X.,Lv, T.,Li, Q.,Liu, W.,Feng, J.,Liu, X.,Yao, P.,Wu, Q.,Zhu, D.; Engineering a Carbonyl Reductase to Simultaneously Increase Activity Toward Bulky Ketone and Isopropanol for Dynamic Kinetic Asymmetric Reduction via Enzymatic Hydrogen Transfer; Acs Catalysis, 13:9960-9968, 2023; DOI: 10.1021/acscatal.3c01569

Experimental method

X-RAY DIFFRACTION (1.63 Å)