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7LK9
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Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 HC + COVD21-C8 LC
分子名称: COV107-23 heavy chain, COVD21-C8 light chain
著者Yuan, M, Zhu, X, Wilson, I.A, Wu, N.C.
登録日2021-02-01
公開日2021-02-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain.
Nat Commun, 12, 2021
7LM8
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BU of 7lm8 by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with two cross-neutralizing antibodies CV38-142 and COVA1-16 Fabs isolated from COVID-19 patients
分子名称: 1,2-ETHANEDIOL, COVA1-16 Fab heavy chain, COVA1-16 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2021-02-05
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.936 Å)
主引用文献A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
Cell Host Microbe, 29, 2021
7LM9
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BU of 7lm9 by Molmil
Crystal structure of SARS-CoV spike protein receptor-binding domain in complex with a cross-neutralizing antibody CV38-142 Fab isolated from COVID-19 patient
分子名称: 1,2-ETHANEDIOL, CV38-142 Fab heavy chain, CV38-142 Fab light chain, ...
著者Liu, H, Yuan, M, Zhu, X, Wilson, I.A.
登録日2021-02-05
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
Cell Host Microbe, 29, 2021
6N5A
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BU of 6n5a by Molmil
Crystal structure of an equine H7 hemagglutinin from A/equine/NY/49/73 (H7N7)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Zhu, X, Wilson, I.A.
登録日2018-11-21
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses.
Cell Rep, 27, 2019
1IAO
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BU of 1iao by Molmil
CLASS II MHC I-AD IN COMPLEX WITH OVALBUMIN PEPTIDE 323-339
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-AD
著者Scott, C.A, Peterson, P.A, Teyton, L, Wilson, I.A.
登録日1998-03-13
公開日1998-11-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues.
Immunity, 8, 1998
1FRG
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BU of 1frg by Molmil
CRYSTAL STRUCTURE, SEQUENCE, AND EPITOPE MAPPING OF A PEPTIDE COMPLEX OF AN ANTI-INFLUENZA HA PEPTIDE ANTIBODY FAB 26(SLASH)9: FINE-TUNING ANTIBODY SPECIFICITY
分子名称: IGG2A 26/9 FAB (HEAVY CHAIN), IGG2A 26/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 101 - 108)
著者Churchill, M.E.A, Wilson, I.A.
登録日1994-01-17
公開日1994-05-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen.
J.Mol.Biol., 241, 1994
8TXM
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BU of 8txm by Molmil
Crystal structure of 05.GC.w13.02 Fab in complex with H1 HA from A/California/04/2009(H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_B, ...
著者Lin, T.H, Moore, N, Wilson, I.A.
登録日2023-08-23
公開日2024-06-26
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Maturation of germinal center B cells after influenza vaccination in humans
J.Exp.Med., 2024
8TXT
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BU of 8txt by Molmil
Crystal structure of 05.GC.w13.02 Fab in complex with H5 HA from A/Viet Nam/1203/2004(H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_W13B_B, ...
著者Lin, T.H, Moore, N, Wilson, I.A.
登録日2023-08-24
公開日2024-06-26
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Maturation of germinal center B cells after influenza vaccination in humans
J.Exp.Med., 2024
8TY7
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BU of 8ty7 by Molmil
Crystal structure of 05.GC.w2.3C10 Fab in complex with H1 HA from A/California/04/2009(H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w2_3C10, heavy chain, ...
著者Lin, T.H, Moore, N, Wilson, I.A.
登録日2023-08-24
公開日2024-06-26
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Maturation of germinal center B cells after influenza vaccination in humans
J.Exp.Med., 2024
8U44
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BU of 8u44 by Molmil
CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06
分子名称: 05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Moore, N, Han, J, Ward, A.B, Wilson, I.A.
登録日2023-09-08
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Persistence of germinal center B cell responses after influenza virus vaccination in humans
To Be Published
8TXP
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BU of 8txp by Molmil
Crystal structure of 05.GC.w13.01 Fab in complex with H1 HA from A/California/04/2009(H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_A, Fab heavy chain, ...
著者Lin, T.H, Moore, N, Wilson, I.A.
登録日2023-08-24
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Maturation of germinal center B cells after influenza vaccination in humans
J.Exp.Med., 2024
3CYE
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BU of 3cye by Molmil
Cyrstal structure of the native 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
著者Zhu, X, Xu, X, Wilson, I.A.
登録日2008-04-25
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure determination of the 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects
Acta Crystallogr.,Sect.D, 64, 2008
8F0I
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BU of 8f0i by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody COVA309-22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA309-22 heavy chain, COVA309-22 light chain, ...
著者Yuan, M, Wilson, I.A.
登録日2022-11-03
公開日2023-09-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Broad SARS-CoV-2 neutralization by monoclonal and bispecific antibodies derived from a Gamma-infected individual.
Iscience, 26, 2023
1IFH
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BU of 1ifh by Molmil
A DETAILED ANALYSIS OF THE FREE AND BOUND CONFORMATION OF AN ANTIBODY: X-RAY STRUCTURES OF ANTI-PEPTIDE FAB 17(SLASH)9 AND THREE DIFFERENT FAB-PEPTIDE COMPLEXES
分子名称: IGG2A-KAPPA 17/9 FAB (HEAVY CHAIN), IGG2A-KAPPA 17/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 101-107)
著者Schulze-Gahmen, U, Wilson, I.A.
登録日1993-05-06
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Detailed analysis of the free and bound conformations of an antibody. X-ray structures of Fab 17/9 and three different Fab-peptide complexes.
J.Mol.Biol., 234, 1993
1GGB
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BU of 1ggb by Molmil
MAJOR ANTIGEN-INDUCED DOMAIN REARRANGEMENTS IN AN ANTIBODY
分子名称: IGG2A-KAPPA 50.1 FAB (HEAVY CHAIN), IGG2A-KAPPA 50.1 FAB (LIGHT CHAIN)
著者Takimoto-Kamimura, M, Wilson, I.A.
登録日1993-07-19
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Major antigen-induced domain rearrangements in an antibody.
Structure, 1, 1993
1GGC
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BU of 1ggc by Molmil
MAJOR ANTIGEN-INDUCED DOMAIN REARRANGEMENTS IN AN ANTIBODY
分子名称: IGG2A-KAPPA 50.1 FAB (HEAVY CHAIN), IGG2A-KAPPA 50.1 FAB (LIGHT CHAIN)
著者Takimoto-Kamimura, M, Wilson, I.A.
登録日1993-07-19
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Major antigen-induced domain rearrangements in an antibody.
Structure, 1, 1993
1GGI
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BU of 1ggi by Molmil
CRYSTAL STRUCTURE OF AN HIV-1 NEUTRALIZING ANTIBODY 50.1 IN COMPLEX WITH ITS V3 LOOP PEPTIDE ANTIGEN
分子名称: HIV-1 V3 LOOP PEPTIDE ANTIGEN, IGG2A 50.1 FAB (HEAVY CHAIN), IGG2A 50.1 FAB (LIGHT CHAIN)
著者Stanfield, R.L, Rini, J.M, Wilson, I.A.
登録日1993-04-02
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen.
Proc.Natl.Acad.Sci.USA, 90, 1993
2FX9
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BU of 2fx9 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41
分子名称: Fab 4E10, Fragment of HIV glycoprotein gp41
著者Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日2006-02-03
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
2FX8
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BU of 2fx8 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41
分子名称: Fab 4E10, Fragment of HIV glycoprotein (GP41)
著者Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日2006-02-03
公開日2006-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
2FX7
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BU of 2fx7 by Molmil
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41
分子名称: Fab 4E10, Fragment of HIV glycoprotein (GP41), GLYCEROL
著者Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日2006-02-03
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
8SDF
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BU of 8sdf by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.4
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yuan, M, Wilson, I.A.
登録日2023-04-06
公開日2024-03-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift.
Biorxiv, 2023
8SDG
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BU of 8sdg by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.43
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neutralizing antibody CC25.43 heavy chain, Neutralizing antibody CC25.43 light chain, ...
著者Yuan, M, Wilson, I.A.
登録日2023-04-06
公開日2024-03-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift.
Biorxiv, 2023
8SD4
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BU of 8sd4 by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule fusion inhibitor compound 7
分子名称: (S~1~S)-N-{3,5-dichloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-[(dimethylamino)methyl]azetidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Kadam, R.U, Zhu, X, Wilson, I.A.
登録日2023-04-06
公開日2024-06-05
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TJA
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BU of 8tja by Molmil
CRYSTAL STRUCTURE OF THE A/Ecuador/1374/2016(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Wu, N.C, Zhu, X, Wilson, I.A.
登録日2023-07-20
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site.
Cell Host Microbe, 32, 2024
8TJ7
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BU of 8tj7 by Molmil
CRYSTAL STRUCTURE OF THE A/Shandong/9/1993(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Zhu, X, Wilson, I.A.
登録日2023-07-20
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site.
Cell Host Microbe, 32, 2024

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