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Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686S Mutant in Complex with Glutamate at 1.7 Resolution
分子名称:	GLUTAMIC ACID, Glutamate receptor 2, SULFATE ION
著者	Cho, Y, Lolis, E, Howe, J.R.
登録日	2007-10-29
公開日	2008-02-05
最終更新日	2021-10-20
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. J.Neurosci., 28, 2008

5V5I

OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.1
分子名称:	RNA-directed RNA polymerase L, Ubiquitin variant CC.1
著者	Khare, B, Mark, B.L.
登録日	2017-03-14
公開日	2017-05-10
最終更新日	2020-01-08
実験手法	X-RAY DIFFRACTION (2.201 Å)
主引用文献	OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.1 To be published

5V5H

OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.2
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, RNA-directed RNA polymerase L, SODIUM ION, ...
著者	Khare, B, Mark, B.L.
登録日	2017-03-14
公開日	2017-05-10
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathog., 13, 2017

5V69

Crystal structure of the Middle East respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant ME.4
分子名称:	CHLORIDE ION, ME.4, MERS-CoV PLpro, ...
著者	Bailey-Elkin, B.A, Mark, B.L.
登録日	2017-03-16
公開日	2017-05-10
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathog., 13, 2017

5V5G

OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.4
分子名称:	1,2-ETHANEDIOL, RNA-directed RNA polymerase L, SODIUM ION, ...
著者	Khare, B, Mark, B.L.
登録日	2017-03-14
公開日	2017-05-10
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathog., 13, 2017

5V6A

Crystal structure of the Middle East respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant ME.2
分子名称:	CHLORIDE ION, CITRATE ANION, ME.2, ...
著者	Bailey-Elkin, B.A, Mark, B.L.
登録日	2017-03-16
公開日	2017-05-10
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathog., 13, 2017

8D95

Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors
分子名称:	Complement factor D, N-(6-bromopyridin-2-yl)-1-[(3-cyanophenyl)acetyl]-L-prolinamide
著者	Raman, K, Babu, Y.S.
登録日	2022-06-09
公開日	2022-11-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.166 Å)
主引用文献	Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022

8DEA

Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors
分子名称:	1-[(3-acetylphenyl)acetyl]-N-(6-bromopyridin-2-yl)-L-prolinamide, Complement factor D, GLYCEROL
著者	Raman, K, Babu, Y.S.
登録日	2022-06-20
公開日	2022-11-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.214 Å)
主引用文献	Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022

8DG6

Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors
分子名称:	1-{2-[(2S)-2-{[(3-chloro-2-fluorophenyl)methyl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl}-1H-indazole-3-carboxamide, Complement factor D
著者	Raman, K, Babu, Y.S.
登録日	2022-06-23
公開日	2022-11-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.986 Å)
主引用文献	Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022

5C7J

CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT
分子名称:	E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C
著者	Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
登録日	2015-06-24
公開日	2016-03-16
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016

8SRO

FoxP3 tetramer on TTTG repeats
分子名称:	DNA 72-mer, Forkhead box protein P3
著者	Leng, F, Hur, S.
登録日	2023-05-05
公開日	2023-10-18
最終更新日	2023-12-27
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	FOXP3 recognizes microsatellites and bridges DNA through multimerization. Nature, 624, 2023

8SRP

FoxP3 forms Ladder-like multimer to bridge TTTG repeats
分子名称:	DNA 72-mer, Forkhead box protein P3
著者	Leng, F, Hur, S.
登録日	2023-05-05
公開日	2023-10-18
最終更新日	2023-12-27
実験手法	ELECTRON MICROSCOPY (3.7 Å)
主引用文献	FOXP3 recognizes microsatellites and bridges DNA through multimerization. Nature, 624, 2023

5HPK

System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: NEDD4L and UbV NL.1
分子名称:	E3 ubiquitin-protein ligase NEDD4-like, Ubiquitin variant NL.1
著者	Wu, K.-P, Mukherjee, M, Mercredi, P.Y, Schulman, B.A.
登録日	2016-01-20
公開日	2016-03-16
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.431 Å)
主引用文献	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016

5HPT

System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1, Ubv P2.3 and UBCH7
分子名称:	NEDD4-like E3 ubiquitin-protein ligase WWP1, Ubiquitin variant P2.3, Ubiquitin-conjugating enzyme E2 L3
著者	Wu, K.-P, Schulman, B.A.
登録日	2016-01-20
公開日	2016-03-16
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.84 Å)
主引用文献	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016

5HPL

System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: Rsp5 and UbV R5.4
分子名称:	Rsp5, Ubiquitin variant R5.4
著者	Wu, K.-P, Kamadurai, H.B, Schulman, B.A.
登録日	2016-01-20
公開日	2016-03-16
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.31 Å)
主引用文献	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016

5HPS

System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1
分子名称:	Ubiquitin variant P1.1, WWP1 HECT
著者	Wu, K.-P, Mercredi, P.Y, Schulman, B.A.
登録日	2016-01-20
公開日	2016-03-16
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016

8JNI

Structure of AE2 in complex with PIP2
分子名称:	Anion exchange protein 2, CHLORIDE ION, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate
著者	Yin, Y.X, Ding, D.
登録日	2023-06-06
公開日	2024-02-07
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Structural and functional insights into the lipid regulation of human anion exchanger 2. Nat Commun, 15, 2024

8JNJ

Structure of R932A/K1147A/H1148A mutant AE2
分子名称:	Anion exchange protein 2
著者	Yin, Y.X, Ding, D.
登録日	2023-06-06
公開日	2024-02-07
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	Structural and functional insights into the lipid regulation of human anion exchanger 2. Nat Commun, 15, 2024

7EQ2

Crystal structure of GDP-bound Rab1a-T75D
分子名称:	(4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, COBALT HEXAMMINE(III), ...
著者	Cao, Y.L, Gu, D.D, Gao, S.
登録日	2021-04-28
公開日	2022-11-02
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (1.55090284 Å)
主引用文献	Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis Nat.Struct.Mol.Biol., 2024

7YR5

Embigin facilitates monocarboxylate transporter 1 localization to plasma membrane and transition to a decoupling state
分子名称:	Embigin, Monocarboxylate transporter 1
著者	Xu, B, Ye, S.
登録日	2022-08-08
公開日	2022-09-28
実験手法	ELECTRON MICROSCOPY (3.63 Å)
主引用文献	Embigin facilitates monocarboxylate transporter 1 localization to the plasma membrane and transition to a decoupling state. Cell Rep, 40, 2022

5ONU

Trimeric OmpU structure
分子名称:	(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, GLYCEROL, LAURYL DIMETHYLAMINE-N-OXIDE, ...
著者	Li, H.Y, Dong, C.J.
登録日	2017-08-04
公開日	2018-01-03
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (2.22 Å)
主引用文献	Crystal structure of the outer membrane protein OmpU from Vibrio cholerae at 2.2 angstrom resolution. Acta Crystallogr D Struct Biol, 74, 2018

4Y07

Crystal structure of the HECT domain of human WWP2
分子名称:	NEDD4-like E3 ubiquitin-protein ligase WWP2
著者	Gong, W, Li, J, Li, Z, Xu, Y.
登録日	2015-02-05
公開日	2015-11-04
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.507 Å)
主引用文献	Structure of the HECT domain of human WWP2 Acta Crystallogr.,Sect.F, 71, 2015

4W82

Enoyl-acyl carrier protein-reductase domain from human fatty acid synthase
分子名称:	CHLORIDE ION, Fatty acid synthase, MAGNESIUM ION, ...
著者	Sippel, K.H, Vyas, N.K, Sankaran, B, Quiocho, F.A.
登録日	2014-08-22
公開日	2014-10-15
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Crystal structure of the human Fatty Acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibition. J.Biol.Chem., 289, 2014

7YTJ

Cryo-EM structure of VTC complex
分子名称:	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, INOSITOL HEXAKISPHOSPHATE, PHOSPHATE ION, ...
著者	Guan, Z.Y, Chen, J, Liu, R.W, Chen, Y.K, Xing, Q, Du, Z.M, Liu, Z.
登録日	2022-08-15
公開日	2023-02-22
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex. Nat Commun, 14, 2023

4FF5

Structure basis of a novel virulence factor GHIP a glycosyl hydrolase 25 of Streptococcus pneumoniae participating in host cell invasion
分子名称:	1,2-ETHANEDIOL, Glycosyl hydrolase 25
著者	Wang, D.
登録日	2012-05-31
公開日	2013-07-17
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.86 Å)
主引用文献	Structural basis of the novel S. pneumoniae virulence factor, GHIP, a glycosyl hydrolase 25 participating in host-cell invasion. Plos One, 8, 2013

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表示件数:	25
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