8JNI

Structure of AE2 in complex with PIP2

Summary for 8JNI

• Entry DOI: 10.2210/pdb8jni/pdb
• EMDB information: 36448
• Descriptor: Anion exchange protein 2, CHLORIDE ION, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate (3 entities in total)
• Functional Keywords: ae2, slc4a2, pip2, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 276518.89

Authors

Yin, Y.X.,Ding, D. (deposition date: 2023-06-06, release date: 2024-02-07)

• Primary citation: Zhang, W.,Ding, D.,Lu, Y.,Chen, H.,Jiang, P.,Zuo, P.,Wang, G.,Luo, J.,Yin, Y.,Luo, J.,Yin, Y.; Structural and functional insights into the lipid regulation of human anion exchanger 2.; Nat Commun, 15:759-759, 2024; PubMed: 38272905; DOI: 10.1038/s41467-024-44966-0

Experimental method

ELECTRON MICROSCOPY (3.2 Å)