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PDB: 13 results

3CLN
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BU of 3cln by Molmil
STRUCTURE OF CALMODULIN REFINED AT 2.2 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, CALMODULIN
Authors:Babu, Y.S, Bugg, C.E, Cook, W.J.
Deposit date:1988-05-11
Release date:1988-07-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of calmodulin refined at 2.2 A resolution.
J.Mol.Biol., 204, 1988
1BIO
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BU of 1bio by Molmil
HUMAN COMPLEMENT FACTOR D IN COMPLEX WITH ISATOIC ANHYDRIDE INHIBITOR
Descriptor: COMPLEMENT FACTOR D, GLYCEROL, ISATOIC ANHYDRIDE
Authors:Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L.
Deposit date:1998-06-18
Release date:1999-06-22
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.
J.Mol.Biol., 282, 1998
1ULA
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BU of 1ula by Molmil
APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS
Descriptor: PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
Authors:Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E.
Deposit date:1991-11-05
Release date:1993-01-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.
Proc.Natl.Acad.Sci.USA, 88, 1991
1ULB
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BU of 1ulb by Molmil
APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS
Descriptor: GUANINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
Authors:Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E.
Deposit date:1991-11-05
Release date:1993-01-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.
Proc.Natl.Acad.Sci.USA, 88, 1991
1NNA
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BU of 1nna by Molmil
THREE-DIMENSIONAL STRUCTURE OF INFLUENZA A N9 NEURAMINIDASE AND ITS COMPLEX WITH THE INHIBITOR 2-DEOXY 2,3-DEHYDRO-N-ACETYL NEURAMINIC ACID
Descriptor: CALCIUM ION, NEURAMINIDASE
Authors:Bossart-Whitaker, P, Carson, M, Babu, Y.S, Smith, C.D, Laver, W.G, Air, G.M.
Deposit date:1993-03-08
Release date:1994-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of influenza A N9 neuraminidase and its complex with the inhibitor 2-deoxy 2,3-dehydro-N-acetyl neuraminic acid.
J.Mol.Biol., 232, 1993
1NNB
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BU of 1nnb by Molmil
THREE-DIMENSIONAL STRUCTURE OF INFLUENZA A N9 NEURAMINIDASE AND ITS COMPLEX WITH THE INHIBITOR 2-DEOXY 2,3-DEHYDRO-N-ACETYL NEURAMINIC ACID
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CALCIUM ION, NEURAMINIDASE
Authors:Bossart-Whitaker, P, Carson, M, Babu, Y.S, Smith, C.D, Laver, W.G, Air, G.M.
Deposit date:1993-03-08
Release date:1994-04-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three-dimensional structure of influenza A N9 neuraminidase and its complex with the inhibitor 2-deoxy 2,3-dehydro-N-acetyl neuraminic acid.
J.Mol.Biol., 232, 1993
2SAS
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BU of 2sas by Molmil
STRUCTURE OF A SARCOPLASMIC CALCIUM-BINDING PROTEIN FROM AMPHIOXUS REFINED AT 2.4 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, SARCOPLASMIC CALCIUM-BINDING PROTEIN
Authors:Cook, W.J, Babu, Y.S, Cox, J.A.
Deposit date:1993-07-30
Release date:1993-10-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a sarcoplasmic calcium-binding protein from amphioxus refined at 2.4 A resolution.
J.Mol.Biol., 229, 1993
1HFD
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BU of 1hfd by Molmil
HUMAN COMPLEMENT FACTOR D IN A P21 CRYSTAL FORM
Descriptor: COMPLEMENT FACTOR D
Authors:Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L.
Deposit date:1998-06-18
Release date:1999-06-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.
J.Mol.Biol., 282, 1998
1DIC
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BU of 1dic by Molmil
STRUCTURE OF 3,4-DICHLOROISOCOUMARIN-INHIBITED FACTOR D
Descriptor: 3,4-DICHLOROISOCOUMARIN, FACTOR D, OXYGEN ATOM
Authors:Cole, L.B, Kilpatrick, J.M, Chu, N, Babu, Y.S.
Deposit date:1998-07-08
Release date:1999-07-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of 3,4-dichloroisocoumarin-inhibited factor D.
Acta Crystallogr.,Sect.D, 54, 1998
1DFP
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BU of 1dfp by Molmil
FACTOR D INHIBITED BY DIISOPROPYL FLUOROPHOSPHATE
Descriptor: DIISOPROPYL PHOSPHONATE, FACTOR D
Authors:Cole, L.B, Chu, N, Kilpatrick, J.M, Volanakis, J.E, Narayana, S.V.L, Babu, Y.S.
Deposit date:1997-02-18
Release date:1998-02-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of diisopropyl fluorophosphate-inhibited factor D.
Acta Crystallogr.,Sect.D, 53, 1997
8DEA
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BU of 8dea by Molmil
Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors
Descriptor: 1-[(3-acetylphenyl)acetyl]-N-(6-bromopyridin-2-yl)-L-prolinamide, Complement factor D, GLYCEROL
Authors:Raman, K, Babu, Y.S.
Deposit date:2022-06-20
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.214 Å)
Cite:Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors.
Bioorg.Med.Chem., 74, 2022
8DG6
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BU of 8dg6 by Molmil
Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors
Descriptor: 1-{2-[(2S)-2-{[(3-chloro-2-fluorophenyl)methyl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl}-1H-indazole-3-carboxamide, Complement factor D
Authors:Raman, K, Babu, Y.S.
Deposit date:2022-06-23
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.986 Å)
Cite:Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors.
Bioorg.Med.Chem., 74, 2022
8D95
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BU of 8d95 by Molmil
Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors
Descriptor: Complement factor D, N-(6-bromopyridin-2-yl)-1-[(3-cyanophenyl)acetyl]-L-prolinamide
Authors:Raman, K, Babu, Y.S.
Deposit date:2022-06-09
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.166 Å)
Cite:Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors.
Bioorg.Med.Chem., 74, 2022

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