1ULB
APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS
Summary for 1ULB
Entry DOI | 10.2210/pdb1ulb/pdb |
Descriptor | PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION, GUANINE (3 entities in total) |
Functional Keywords | pentosyltransferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton (By similarity): P00491 |
Total number of polymer chains | 1 |
Total formula weight | 32528.13 |
Authors | Ealick, S.E.,Rule, S.A.,Carter, D.C.,Greenhough, T.J.,Babu, Y.S.,Cook, W.J.,Habash, J.,Helliwell, J.R.,Stoeckler, J.D.,Parksjunior, R.E.,Chen, S.-F.,Bugg, C.E. (deposition date: 1991-11-05, release date: 1993-01-15, Last modification date: 2024-02-14) |
Primary citation | Ealick, S.E.,Babu, Y.S.,Bugg, C.E.,Erion, M.D.,Guida, W.C.,Montgomery, J.A.,Secrist 3rd., J.A. Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors. Proc.Natl.Acad.Sci.USA, 88:11540-11544, 1991 Cited by PubMed: 1763067DOI: 10.1073/pnas.88.24.11540 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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