5V5G

OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.4

Summary for 5V5G

• Entry DOI: 10.2210/pdb5v5g/pdb
• Related: 5V5H 5V5I
• Descriptor: RNA-directed RNA polymerase L, Ubiquitin variant CC.4, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: ovarian tumor domain protease, deubiquitinase, ubiquitin variant, hydrolase, transferase
• Biological source: Crimean-Congo hemorrhagic fever virus (strain Nigeria/IbAr10200/1970) (CCHFV); More
• Total number of polymer chains: 4
• Total formula weight: 66696.08

Authors

Khare, B.,Mark, B.L. (deposition date: 2017-03-14, release date: 2017-05-10, Last modification date: 2023-10-04)

• Primary citation: Zhang, W.,Bailey-Elkin, B.A.,Knaap, R.C.M.,Khare, B.,Dalebout, T.J.,Johnson, G.G.,van Kasteren, P.B.,McLeish, N.J.,Gu, J.,He, W.,Kikkert, M.,Mark, B.L.,Sidhu, S.S.; Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.; PLoS Pathog., 13:e1006372-e1006372, 2017; PubMed: 28542609; DOI: 10.1371/journal.ppat.1006372

Experimental method

X-RAY DIFFRACTION (2.1 Å)