5V5G
OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.4
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 201 |
| Chain | Residue |
| A | ARG92 |
| A | MET93 |
| A | GLU98 |
| A | TRP99 |
| A | SER101 |
| A | GLU104 |
| B | ARG72 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 202 |
| Chain | Residue |
| A | MET1 |
| D | PHE4 |
| A | GLY-2 |
| A | GLY0 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 101 |
| Chain | Residue |
| A | HOH308 |
| B | LYS27 |
| B | LEU50 |
| B | ASP52 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 102 |
| Chain | Residue |
| B | ASN60 |
| B | GLN62 |
| B | HOH222 |
| C | ALA79 |
| C | LEU84 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue NA C 201 |
| Chain | Residue |
| A | ARG63 |
| C | TYR60 |
| C | ARG63 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 202 |
| Chain | Residue |
| C | ARG92 |
| C | MET93 |
| C | GLU98 |
| C | TRP99 |
| C | SER101 |
| C | GLU104 |
| D | ARG72 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue NA C 203 |
| Chain | Residue |
| C | GLY-2 |
| C | GLY0 |
| C | MET1 |
| C | PHE161 |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| B | LYS27-ASP52 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 54 |
| Details | Region: {"description":"Essential for the vOTU enzymatic activity","evidences":[{"source":"PubMed","id":"21266548","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"For ubiquitin thioesterase activity","evidences":[{"source":"PubMed","id":"21228232","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21266548","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For ubiquitin thioesterase activity","evidences":[{"source":"PubMed","id":"21228232","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21266548","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18078692","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
