7EQ2

Crystal structure of GDP-bound Rab1a-T75D

Summary for 7EQ2

• Entry DOI: 10.2210/pdb7eq2/pdb
• Descriptor: Ras-related protein Rab-1A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: ras-related protein rab-1a, small gtpase, protein trafficking, signal transduction, membrane remolding, cell cycle
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 44315.55

Authors

Cao, Y.L.,Gu, D.D.,Gao, S. (deposition date: 2021-04-28, release date: 2022-11-02, Last modification date: 2024-01-10)

• Primary citation: Zhang, W.,Zhang, Z.,Xiang, Y.,Gu, D.D.,Chen, J.,Chen, Y.,Zhai, S.,Liu, Y.,Jiang, T.,Liu, C.,He, B.,Yan, M.,Wang, Z.,Xu, J.,Cao, Y.L.,Deng, B.,Zeng, D.,Lei, J.,Zhuo, J.,Lei, X.,Long, Z.,Jin, B.,Chen, T.,Li, D.,Shen, Y.,Hu, J.,Gao, S.,Liu, Q.; Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis; Nat.Struct.Mol.Biol., 2024; DOI: 10.1038/s41594-023-01165-7

Experimental method

X-RAY DIFFRACTION (1.55090284637 Å)