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1LOJ
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BU of 1loj by Molmil
Crystal structure of a Methanobacterial Sm-like archaeal protein (SmAP1) bound to uridine-5'-monophosphate (UMP)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, URIDINE, URIDINE-5'-MONOPHOSPHATE, ...
著者Mura, C, Kozhukhovsky, A, Eisenberg, D.
登録日2002-05-06
公開日2003-03-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
4RIK
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BU of 4rik by Molmil
Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77
分子名称: Alpha-synuclein
著者Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S.
登録日2014-10-06
公開日2015-08-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.854 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
6CF4
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BU of 6cf4 by Molmil
Segment NFGTFS, with familial mutation A315T and phosphorylated threonine, from the low complexity domain of TDP-43, residues 312-317
分子名称: NFGTFS
著者Guenther, E.L, Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-13
公開日2018-05-23
最終更新日2021-06-30
実験手法ELECTRON CRYSTALLOGRAPHY (0.75 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5KMZ
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BU of 5kmz by Molmil
Solution NMR structure of Tetrahymena telomerase RNA pseudoknot
分子名称: Telomerase RNA pseudoknot
著者Cash, D.D, Feigon, J.
登録日2016-06-27
公開日2016-10-12
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Science, 350, 2015
1M5Q
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BU of 1m5q by Molmil
Crystal structure of a novel Sm-like archaeal protein from Pyrobaculum aerophilum
分子名称: ACETIC ACID, CADMIUM ION, GLYCEROL, ...
著者Mura, C, Phillips, M, Kozhukhovsky, A, Eisenberg, D.
登録日2002-07-09
公開日2003-03-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and assembly of an augmented Sm-like archaeal protein 14-mer
Proc.Natl.Acad.Sci.USA, 100, 2003
4QXX
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BU of 4qxx by Molmil
Structure of the amyloid forming peptide GNLVS (residues 26-30) from the eosinophil major basic protein (EMBP)
分子名称: Bone marrow proteoglycan
著者Soriaga, A.B, Soragni, A, Sawaya, M.R, Eisenberg, D.
登録日2014-07-22
公開日2015-03-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.445 Å)
主引用文献Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation.
Mol.Cell, 57, 2015
4IOD
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BU of 4iod by Molmil
Preliminary structural investigations of a malarial protein secretion system.
分子名称: Malarial CLP B2 atpase/HSP101 protein, SULFATE ION
著者Egea, P.F.
登録日2013-01-07
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
Protein Sci., 24, 2015
3PZZ
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BU of 3pzz by Molmil
Structure of an amyloid forming peptide GAIIGL (29-34) from amyloid beta
分子名称: Amyloid beta A4 protein
著者Soriaga, A.B, Laganowsky, A.L, Sawaya, M.R, Eisenberg, D.
登録日2010-12-14
公開日2011-10-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Molecular basis for amyloid-beta polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q2X
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BU of 3q2x by Molmil
Structure of an amyloid forming peptide NKGAII (residues 27-32) from amyloid beta
分子名称: Amyloid beta A4 protein
著者Soriaga, A.B, Sawaya, M.R, Eisenberg, D.
登録日2010-12-20
公開日2011-10-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Molecular basis for amyloid-beta polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
4IRF
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BU of 4irf by Molmil
Preliminary structural investigations of a malarial protein secretion system
分子名称: MALARIAL CLPB2 ATPASE/HSP101 PROTEIN
著者Egea, P.F.
登録日2013-01-14
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
Protein Sci., 24, 2015
4UNU
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BU of 4unu by Molmil
MCG - a dimer of lambda variable domains
分子名称: IG LAMBDA CHAIN V-II REGION MGC, POLYETHYLENE GLYCOL (N=34), SULFATE ION
著者Brumshtein, B, Esswein, S.R, Landau, M, Ryan, C, Whitelegge, J, Casio, D, Sawaya, M.R, Eisenberg, D.S.
登録日2014-05-30
公開日2014-08-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
3OW9
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BU of 3ow9 by Molmil
Structure of an amyloid forming peptide KLVFFA from amyloid beta, alternate polymorph II
分子名称: KLVFFA hexapeptide segment from Amyloid beta
著者Landau, M, Eisenberg, D.
登録日2010-09-17
公開日2011-08-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular basis for amyloid-{beta} polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
2LGS
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BU of 2lgs by Molmil
FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE
分子名称: GLUTAMIC ACID, GLUTAMINE SYNTHETASE, MANGANESE (II) ION
著者Liaw, S.-H, Eisenberg, D.
登録日1994-08-05
公開日1994-11-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Feedback inhibition of fully unadenylylated glutamine synthetase from Salmonella typhimurium by glycine, alanine, and serine.
Proc.Natl.Acad.Sci.USA, 90, 1993
6WLA
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BU of 6wla by Molmil
Antigen binding fragment of ch128.1
分子名称: Fab ch128.1 heavy chain, Fab ch128.1 light chain, GLYCEROL
著者Helguera, G, Rodriguez, J.A, Sawaya, M, Cascio, D, Zink, S, Ziegenbein, J, Short, C.
登録日2020-04-18
公開日2021-03-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections.
Nat Commun, 13, 2022
3NVF
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BU of 3nvf by Molmil
IIHFGS segment 138-143 from human prion
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVE
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BU of 3nve by Molmil
MMHFGN segment 138-143 from Syrian Hamster prion
分子名称: Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVG
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BU of 3nvg by Molmil
MIHFGN segment 137-142 from mouse prion
分子名称: Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
6CEW
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BU of 6cew by Molmil
Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326
分子名称: AMMAAA
著者Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-12
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6CFH
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BU of 6cfh by Molmil
SWGMMGMLASQ segment from the low complexity domain of TDP-43
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Rodriguez, J.A, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-15
公開日2018-05-23
最終更新日2024-05-15
実験手法ELECTRON CRYSTALLOGRAPHY (1.5 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6BTK
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BU of 6btk by Molmil
Segment from bank vole prion protein 168-176 QYNNQNNFV
分子名称: Major prion protein
著者Glynn, C, Rodriguez, J.A, Boyer, D.R, Gallagher-Jones, M.
登録日2017-12-06
公開日2018-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Sub-angstrom cryo-EM structure of a prion protofibril reveals a polar clasp.
Nat. Struct. Mol. Biol., 25, 2018
5VL4
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BU of 5vl4 by Molmil
Accidental minimum contact crystal lattice formed by a redesigned protein oligomer
分子名称: T33-53H-B
著者Cannon, K.A, Cascio, D, Sawaya, M.R, Park, R, Boyken, S, King, N, Yeates, T.
登録日2017-04-24
公開日2018-05-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering.
Protein Sci., 29, 2020
6CB9
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BU of 6cb9 by Molmil
Segment AALQSS from the low complexity domain of TDP-43, residues 328-333
分子名称: AALQSS
著者Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-02
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
3O7O
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BU of 3o7o by Molmil
Use of synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga maritima
分子名称: BROMIDE ION, Endoglucanase
著者Forse, G.J, Ram, N, Yeates, T.O.
登録日2010-07-30
公開日2010-12-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga maritima.
Protein Sci., 20, 2011
1RHG
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BU of 1rhg by Molmil
THE STRUCTURE OF GRANULOCYTE-COLONY-STIMULATING FACTOR AND ITS RELATIONSHIP TO THOSE OF OTHER GROWTH FACTORS
分子名称: GRANULOCYTE COLONY-STIMULATING FACTOR
著者Hill, C.P, Osslund, T.D, Eisenberg, D.
登録日1993-01-29
公開日1994-01-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors.
Proc.Natl.Acad.Sci.USA, 90, 1993
1SK5
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BU of 1sk5 by Molmil
The ultra-high resolution structure of d(CTTTTAAAAG)2: modulation of bending by T-A steps and its role in DNA recognition
分子名称: 5'-D(*CP*TP*TP*TP*TP*AP*AP*AP*AP*G)-3', CALCIUM ION
著者Han, G.W, Langs, D, Kopka, M.L, Dickerson, R.E.
登録日2004-03-04
公開日2005-06-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (0.89 Å)
主引用文献The ultra-high resolution structure of d(CTTTTAAAAG)2: modulation of bending by T-A steps and its role in DNA recognition
To be Published

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