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1PKK
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Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Bifunctional deaminase/diphosphatase
著者Huffman, J.L, Li, H, White, R.H, Tainer, J.A.
登録日2003-06-05
公開日2003-09-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii
J.Mol.Biol., 331, 2003
1YHY
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BU of 1yhy by Molmil
Crystal structure of Arabidopsis thaliana Acetohydroxyacid synthase In Complex With A Sulfonylurea Herbicide, Metsulfuron methyl
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ETHYL DIHYDROGEN DIPHOSPHATE, ...
著者McCourt, J.A, Pang, S.S, King-Scott, J, Guddat, L.W, Duggleby, R.G.
登録日2005-01-10
公開日2006-01-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase
Proc.Natl.Acad.Sci.Usa, 103, 2006
2VK5
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THE STRUCTURE OF CLOSTRIDIUM PERFRINGENS NANI SIALIDASE AND ITS CATALYTIC INTERMEDIATES
分子名称: CALCIUM ION, EXO-ALPHA-SIALIDASE, GLYCEROL
著者Newstead, S.L, Potter, J.A, Wilson, J.C, Xu, G, Chien, C.H, Watts, A.G, Withers, S.G, Taylor, G.L.
登録日2007-12-17
公開日2008-01-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献The Structure of Clostridium Perfringens Nani Sialidase and its Catalytic Intermediates.
J.Biol.Chem., 283, 2008
4EEL
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BU of 4eel by Molmil
Crystal structure of HAD FAMILY HYDROLASE DR_1622 from Deinococcus radiodurans R1 (TARGET EFI-501256) with bound citrate and sodium
分子名称: Beta-phosphoglucomutase-related protein, CITRIC ACID, SODIUM ION
著者Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Allen, K.N, Dunaway-Mariano, D, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-03-28
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of HAD HYDROLASE DR_1622 Deinococcus radiodurans R1 (TARGET EFI-501256)
To be Published
1AF8
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ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR A3(2), NMR, 24 STRUCTURES
分子名称: ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN
著者Crump, M.P, Crosby, J, Dempsey, C.E, Parkinson, J.A, Murray, M, Hopwood, D.A, Simpson, T.J.
登録日1997-03-23
公開日1997-09-26
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2).
Biochemistry, 36, 1997
4EB1
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BU of 4eb1 by Molmil
Hyperstable in-frame insertion variant of antithrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III
著者Martinez-Martinez, I, Johnson, D.J.D, Yamasaki, M, Corral, J, Huntington, J.A.
登録日2012-03-23
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Type II antithrombin deficiency caused by a large in-frame insertion: structural, functional and pathological relevance.
J.Thromb.Haemost., 10, 2012
4EBP
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BlaC E166A Cefotaxime Acyl-Intermediate Complex
分子名称: Beta-lactamase, CEFOTAXIME, C3' cleaved, ...
著者Mire, J.A, TB Structural Genomics Consortium (TBSGC)
登録日2012-03-23
公開日2013-04-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Faropenem is Effective Against Mycobacterium tuberculosis in vitro and in vivo
To be Published
1YBH
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BU of 1ybh by Molmil
Crystal structure of Arabidopsis thaliana Acetohydroxyacid synthase In Complex With A Sulfonylurea Herbicide Chlorimuron Ethyl
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-[[[[(4-CHLORO-6-METHOXY-2-PYRIMIDINYL)AMINO]CARBONYL]AMINO]SULFONYL]BENZOIC ACID ETHYL ESTER, Acetolactate synthase, ...
著者McCourt, J.A, Pang, S.S, King-Scott, J, Guddat, L.W, Duggleby, R.G.
登録日2004-12-20
公開日2006-01-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase
Proc.Natl.Acad.Sci.Usa, 103, 2006
4ENM
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Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-benzylguanine
分子名称: Alkyltransferase-like protein 1, DNA (5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*AP*TP*GP*(BZG)P*CP*TP*AP*GP*TP*A)-3')
著者Tubbs, J.L, Arvai, A.S, Tainer, J.A.
登録日2012-04-13
公開日2012-06-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8402 Å)
主引用文献Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines.
Mol.Cell, 47, 2012
2W22
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Activation Mechanism of Bacterial Thermoalkalophilic Lipases
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL, CALCIUM ION, ...
著者Carrasco-Lopez, C, Godoy, C, De Las Rivas, B, Fernandez-Lorente, G, Palomo, J.M, Guisan, J.M, Fernandez-Lafuente, R, Hermoso, J.A.
登録日2008-10-23
公開日2008-12-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Activation of bacterial thermoalkalophilic lipases is spurred by dramatic structural rearrangements.
J. Biol. Chem., 284, 2009
2VR9
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BU of 2vr9 by Molmil
Drosophila Robo IG1-2 (tetragonal form)
分子名称: ROUNDABOUT 1
著者Fukuhara, N, Howitt, J.A, Hussain, S, Hohenester, E.
登録日2008-03-28
公開日2008-04-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and Functional Analysis of Slit and Heparin Binding to Immunoglobulin-Like Domains 1 and 2 of Drosophila Robo
J.Biol.Chem., 283, 2008
4ENK
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Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-propylguanine
分子名称: Alkyltransferase-like protein 1, DNA (5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6PO)P*CP*TP*AP*GP*TP*A)-3')
著者Tubbs, J.L, Arvai, A.S, Tainer, J.A.
登録日2012-04-13
公開日2012-06-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.0445 Å)
主引用文献Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines.
Mol.Cell, 47, 2012
2VR8
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BU of 2vr8 by Molmil
Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.36 A resolution
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J.
登録日2008-03-28
公開日2008-04-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
2VW2
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BU of 2vw2 by Molmil
Crystal structure of the NanB sialidase from Streptococcus pneumoniae
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, SIALIDASE B
著者Xu, G, Potter, J.A, Russell, R.J.M, Oggioni, M.R, Andrew, P.W, Taylor, G.L.
登録日2008-06-13
公開日2008-06-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of the Nanb Sialidase from Streptococcus Pneumoniae
J.Mol.Biol., 384, 2008
1B39
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HUMAN CYCLIN-DEPENDENT KINASE 2 PHOSPHORYLATED ON THR 160
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (CELL DIVISION PROTEIN KINASE 2)
著者Brown, N.R, Noble, M.E.M, Lawrie, A.M, Morris, M.C, Tunnah, P, Divita, G, Johnson, L.N, Endicott, J.A.
登録日1998-12-17
公開日1998-12-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity.
J.Biol.Chem., 274, 1999
4E8G
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BU of 4e8g by Molmil
Crystal structure of an enolase (mandelate racemase subgroup) from paracococus denitrificans pd1222 (target nysgrc-012907) with bound mg
分子名称: MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein, ...
著者Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Chamala, S, Kar, A, Lafleur, J, Villigas, G, Evans, B, Hammonds, J, Gizzi, A, Zencheck, W.D, Hillerich, B, Love, J, Seidel, R.D, Bonanno, J.B, Gerlt, J.A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-03-20
公開日2012-05-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine.
MBio, 5, 2014
4DY7
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BU of 4dy7 by Molmil
Crystal structures of protease nexin-1 in complex with S195A thrombin
分子名称: ACETATE ION, CALCIUM ION, Glia-derived nexin, ...
著者Huntington, J.A, Li, W.
登録日2012-02-28
公開日2012-08-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism.
Blood, 120, 2012
2W2A
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BU of 2w2a by Molmil
Crystal Structure of p-coumaric Acid Decarboxylase from Lactobacillus plantarum: structural insights into the active site and decarboxylation catalytic mechanism
分子名称: P-COUMARIC ACID DECARBOXYLASE
著者Rodriguez, H, Angulo, I, de las Rivas, B, Campillo, N, Paez, J.A, Munoz, R, Mancheno, J.M.
登録日2008-10-27
公開日2009-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献P-Coumaric Acid Decarboxylase from Lactobacillus Plantarum: Structural Insights Into the Active Site and Decarboxylation Catalytic Mechanism.
Proteins, 78, 2010
2W40
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Crystal structure of Plasmodium falciparum glycerol kinase with bound glycerol
分子名称: 1,2-ETHANEDIOL, GLYCEROL, GLYCEROL KINASE, ...
著者Schnick, C, Polley, S.D, Fivelman, Q.L, Ranford-Cartwright, L, Wilkinson, S.R, Brannigan, J.A, Wilkinson, A.J, Baker, D.A.
登録日2008-11-18
公開日2008-12-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structure and Non-Essential Function of Glycerol Kinase in Plasmodium Falciparum Blood Stages.
Mol.Microbiol., 71, 2009
1YO1
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Proton Transfer from His200 in Human Carbonic Anhydrase II
分子名称: Carbonic anhydrase II, SULFATE ION, ZINC ION
著者Bhatt, D, Tu, C, Fisher, S.Z, Hernandez Prada, J.A, McKenna, R, Silverman, D.N.
登録日2005-01-26
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Proton transfer in a Thr200His mutant of human carbonic anhydrase II
Proteins, 61, 2005
4DN1
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Crystal structure of an ENOLASE (mandelate racemase subgroup member) from Agrobacterium tumefaciens (target EFI-502088) with bound mg and formate
分子名称: CHLORIDE ION, FORMIC ACID, Isomerase/lactonizing enzyme, ...
著者Vetting, M.W, Toro, R, Bhosle, R, Bouvier, J.T, Wasserman, S.R, Morisco, L.L, Sojitra, S, Al Obaidi, N.F, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-02-08
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of an enolase (mandelate racemase subgroup member) from Agrobacterium tumefaciens (target EFI-502088) with bound mg and formate
to be published
2WMA
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Structural and thermodynamic consequences of cyclization of peptide ligands for the recruitment site of cyclin A
分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIC RKLFN-NH2, CYCLIN-A2
著者Robertson, G.F, Endicott, J.A, Noble, M.E.M, McDonnell, J.M.
登録日2009-06-30
公開日2010-09-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and Thermodynamic Consequences of Cyclization of Peptide Ligands for the Recruitment Site of Cyclin A
To be Published
4DPP
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The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana
分子名称: Dihydrodipicolinate synthase 2, chloroplastic, SODIUM ION
著者Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G.
登録日2012-02-14
公開日2012-07-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana
Plos One, 7, 2012
1YOW
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human Steroidogenic Factor 1 LBD with bound Co-factor Peptide
分子名称: PHOSPHATIDYL ETHANOL, Steroidogenic factor 1, TIF2 peptide
著者Krylova, I.N, Sablin, E.P, Xu, R.X, Waitt, G.M, Juzumiene, D, Williams, J.D, Ingraham, H.A, Willson, T.M, Williams, S.P, Montana, V, Madauss, K.P, Moore, J, Bynum, J.M, Lebedeva, L, MacKay, J.A, Suzawa, M, Guy, R.K, Thornton, J.W.
登録日2005-01-28
公開日2005-05-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
Cell(Cambridge,Mass.), 120, 2005
1NZN
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Cytosolic domain of the human mitchondrial fission protein Fis1 adopts a TPR fold
分子名称: Fission protein Fis1p, GLYCEROL, SULFATE ION
著者Gittis, A.G, Dohm, J.A, Hill, R.B.
登録日2003-02-18
公開日2004-03-02
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cytosolic domain of the human mitchondrial fission protein Fis1 adopts a TPR fold
Proteins, 54, 2004

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