1G55
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![BU of 1g55 by Molmil](/molmil-images/mine/1g55) | Structure of human DNMT2, an enigmatic DNA methyltransferase homologue | 分子名称: | BETA-MERCAPTOETHANOL, DNA CYTOSINE METHYLTRANSFERASE DNMT2, GLYCEROL, ... | 著者 | Dong, A, Yoder, J.A, Zhang, X, Zhou, L, Bestor, T.H, Cheng, X. | 登録日 | 2000-10-30 | 公開日 | 2001-01-17 | 最終更新日 | 2018-06-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA. Nucleic Acids Res., 29, 2001
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5IJD
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![BU of 5ijd by Molmil](/molmil-images/mine/5ijd) | The crystal structure of mouse TLR4/MD-2/lipid A complex | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | 登録日 | 2016-03-01 | 公開日 | 2016-04-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
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5ZC3
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1JQD
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![BU of 1jqd by Molmil](/molmil-images/mine/1jqd) | Crystal Structure Analysis of Human Histamine Methyltransferase (Thr105 Polymorphic Variant) Complexed with AdoHcy and Histamine | 分子名称: | HISTAMINE, Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X. | 登録日 | 2001-08-06 | 公開日 | 2002-08-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons. Structure, 9, 2001
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1V92
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![BU of 1v92 by Molmil](/molmil-images/mine/1v92) | Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97 | 分子名称: | NSFL1 cofactor p47 | 著者 | Yuan, X, Simpson, P, Mckeown, C, Kondo, H, Uchiyama, K, Wallis, R, Dreveny, I, Keetch, C, Zhang, X, Robinson, C, Freemont, P, Matthews, S. | 登録日 | 2004-01-19 | 公開日 | 2004-04-06 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97 Embo J., 23, 2004
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6NT9
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![BU of 6nt9 by Molmil](/molmil-images/mine/6nt9) | Cryo-EM structure of the complex between human TBK1 and chicken STING | 分子名称: | Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein | 著者 | Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. | 登録日 | 2019-01-28 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of STING binding with and phosphorylation by TBK1. Nature, 567, 2019
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5ZG9
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![BU of 5zg9 by Molmil](/molmil-images/mine/5zg9) | Crystal structure of MoSub1-ssDNA complex in phosphate buffer | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*G)-3'), MoSub1, PHOSPHATE ION | 著者 | Zhao, Y, Huang, J, Liu, H, Yi, L, Wang, S, Zhang, X, Liu, J. | 登録日 | 2018-03-08 | 公開日 | 2019-03-27 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | The effect of phosphate ion on the ssDNA binding mode of MoSub1, a Sub1/PC4 homolog from rice blast fungus. Proteins, 87, 2019
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1VAZ
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![BU of 1vaz by Molmil](/molmil-images/mine/1vaz) | Solution structures of the p47 SEP domain | 分子名称: | NSFL1 cofactor p47 | 著者 | Yuan, X, Simpson, P, Mckeown, C, Kondo, H, Uchiyama, K, Wallis, R, Dreveny, I, Keetch, C, Zhang, X, Robinson, C, Freemont, P, Matthews, S. | 登録日 | 2004-02-20 | 公開日 | 2004-04-06 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97. Embo J., 23, 2004
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1U2Z
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![BU of 1u2z by Molmil](/molmil-images/mine/1u2z) | Crystal structure of histone K79 methyltransferase Dot1p from yeast | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X. | 登録日 | 2004-07-20 | 公開日 | 2004-09-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase J.Biol.Chem., 279, 2004
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1NGN
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![BU of 1ngn by Molmil](/molmil-images/mine/1ngn) | Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 | 分子名称: | methyl-CpG binding protein MBD4 | 著者 | Wu, P, Qiu, C, Sohail, A, Zhang, X, Bhagwat, A.S, Cheng, X. | 登録日 | 2002-12-17 | 公開日 | 2003-03-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 J.Biol.Chem., 278, 2003
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1KHC
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![BU of 1khc by Molmil](/molmil-images/mine/1khc) | Crystal Structure of the PWWP Domain of Mammalian DNA Methyltransferase Dnmt3b | 分子名称: | DNA cytosine-5 methyltransferase 3B2, UNKNOWN ATOM OR ION | 著者 | Qiu, C, Sawada, K, Zhang, X, Cheng, X. | 登録日 | 2001-11-29 | 公開日 | 2002-02-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds. Nat.Struct.Biol., 9, 2002
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4QWQ
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![BU of 4qwq by Molmil](/molmil-images/mine/4qwq) | Crystal structure of the DNA-binding domain of the response regulator SaeR from Staphylococcus aureus | 分子名称: | Response regulator SaeR | 著者 | Fan, X, Zhu, Y, Zhang, X, Teng, M, Li, X. | 登録日 | 2014-07-17 | 公開日 | 2015-08-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Structure of the DNA-binding domain of the response regulator SaeR from Staphylococcus aureus. Acta Crystallogr.,Sect.D, 71, 2015
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2W5Q
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![BU of 2w5q by Molmil](/molmil-images/mine/2w5q) | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | 分子名称: | 1,2-ETHANEDIOL, MANGANESE (II) ION, PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE | 著者 | Lu, D, Wormann, M.E, Zhang, X, Scheewind, O, Grundling, A, Freemont, P.S. | 登録日 | 2008-12-11 | 公開日 | 2009-02-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas. Proc.Natl.Acad.Sci.USA, 106, 2009
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1MVX
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![BU of 1mvx by Molmil](/molmil-images/mine/1mvx) | structure of the SET domain histone lysine methyltransferase Clr4 | 分子名称: | CRYPTIC LOCI REGULATOR 4, NICKEL (II) ION, SULFATE ION, ... | 著者 | Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M. | 登録日 | 2002-09-26 | 公開日 | 2002-10-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the SET domain histone lysine methyltransferase Clr4. Nat.Struct.Biol., 9, 2002
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1MVH
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![BU of 1mvh by Molmil](/molmil-images/mine/1mvh) | structure of the SET domain histone lysine methyltransferase Clr4 | 分子名称: | Cryptic loci regulator 4, NICKEL (II) ION, SULFATE ION, ... | 著者 | Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M. | 登録日 | 2002-09-25 | 公開日 | 2002-10-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the SET domain histone lysine methyltransferase Clr4. Nat.Struct.Biol., 9, 2002
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2XDN
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2XRN
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![BU of 2xrn by Molmil](/molmil-images/mine/2xrn) | Crystal structure of TtgV | 分子名称: | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV | 著者 | Lu, D, Fillet, S, Meng, C, Alguel, Y, Kloppsteck, P, Bergeron, J, Krell, T, Gallegos, M.-T, Ramos, J, Zhang, X. | 登録日 | 2010-09-17 | 公開日 | 2010-12-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structure of Ttgv in Complex with its DNA Operator Reveals a General Model for Cooperative DNA Binding of Tetrameric Gene Regulators. Genes Dev., 24, 2010
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8H6K
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![BU of 8h6k by Molmil](/molmil-images/mine/8h6k) | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
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8H6J
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![BU of 8h6j by Molmil](/molmil-images/mine/8h6j) | Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
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8H6E
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![BU of 8h6e by Molmil](/molmil-images/mine/8h6e) | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-17 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
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8H6L
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![BU of 8h6l by Molmil](/molmil-images/mine/8h6l) | Cryo-EM structure of human exon-defined spliceosome in the early B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
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2XRO
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![BU of 2xro by Molmil](/molmil-images/mine/2xro) | Crystal structure of TtgV in complex with its DNA operator | 分子名称: | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV, OSMIUM ION, TTGV OPERATOR DNA | 著者 | Lu, D, Fillet, S, Meng, C, Alguel, Y, Kloppsteck, P, Bergeron, J, Krell, T, Gallegos, M.-T, Ramos, J, Zhang, X. | 登録日 | 2010-09-17 | 公開日 | 2010-12-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal Structure of Ttgv in Complex with its DNA Operator Reveals a General Model for Cooperative DNA Binding of Tetrameric Gene Regulators. Genes Dev., 24, 2010
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2WUI
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![BU of 2wui by Molmil](/molmil-images/mine/2wui) | Crystal Structure of MexZ, a key repressor responsible for antibiotic resistance in Pseudomonas aeruginosa. | 分子名称: | TRANSCRIPTIONAL REGULATOR | 著者 | Alguel, Y, Lu, D, Quade, N, Zhang, X. | 登録日 | 2009-10-05 | 公開日 | 2010-08-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structure of Mexz, a Key Repressor Responsible for Antibiotic Resistance in Pseudomonas Aeruginosa. J.Struct.Biol., 172, 2010
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8B4J
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8B4K
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