7CAG
 
 | | Mycobacterium smegmatis LpqY-SugABC complex in the catalytic intermediate state | | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | | 著者 | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T. | | 登録日 | 2020-06-08 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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7CAD
 | | Mycobacterium smegmatis SugABC complex | | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | | 著者 | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | | 登録日 | 2020-06-08 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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7CAE
 | | Mycobacterium smegmatis LpqY-SugABC complex in the resting state | | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | | 著者 | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | | 登録日 | 2020-06-08 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
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7V9G
 | | Native BEN4 domain of protein Bend3 with DNA | | 分子名称: | BEN domain-containing protein 3, DNA (5'-D(*GP*CP*AP*CP*CP*GP*CP*GP*TP*GP*GP*GP*GP*CP*CP*A)-3'), DNA (5'-D(*TP*GP*GP*CP*CP*CP*CP*AP*CP*GP*CP*GP*GP*TP*GP*C)-3') | | 著者 | Zhang, J, Zhang, Y, You, Q, Huang, C, Zhang, T, Wang, M, Zhang, T, Yang, X, Xiong, J, Li, Y, Liu, C.P, Zhang, Z, Xu, R.M, Zhu, B. | | 登録日 | 2021-08-25 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Highly enriched BEND3 prevents the premature activation of bivalent genes during differentiation.
Science, 375, 2022
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7V9I
 | | The Monomer mutant of BEN4 domain of protein Bend3 with DNA | | 分子名称: | BEN domain-containing protein 3, DNA (5'-D(*AP*CP*CP*GP*CP*GP*TP*GP*GP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*CP*CP*AP*CP*GP*CP*GP*GP*T)-3') | | 著者 | Zhang, J, Zhang, Y, You, Q, Huang, C, Zhang, T, Wang, M, Zhang, T, Yang, X, Xiong, J, Li, Y, Liu, C.P, Zhang, Z, Xu, R.M, Zhu, B. | | 登録日 | 2021-08-25 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Highly enriched BEND3 prevents the premature activation of bivalent genes during differentiation.
Science, 375, 2022
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7V9H
 | | The BEN3 domain of protein Bend3 | | 分子名称: | BEN domain-containing protein 3 | | 著者 | Zhang, J, Zhang, Y, You, Q, Huang, C, Zhang, T, Wang, M, Zhang, T, Yang, X, Xiong, J, Li, Y, Liu, C.P, Zhang, Z, Xu, R.M, Zhu, B. | | 登録日 | 2021-08-25 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.692 Å) | | 主引用文献 | Highly enriched BEND3 prevents the premature activation of bivalent genes during differentiation.
Science, 375, 2022
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7V9F
 | | Selenomethionine mutant (L740Sem) of BEN4 domain of protein Bend3 with DNA | | 分子名称: | BEN domain-containing protein 3, CITRIC ACID, DNA (5'-D(*GP*CP*AP*CP*CP*GP*CP*GP*TP*GP*GP*GP*GP*CP*CP*A)-3'), ... | | 著者 | Zhang, J, Zhang, Y, You, Q, Huang, C, Zhang, T, Wang, M, Zhang, T, Yang, X, Xiong, J, Li, Y, Liu, C.P, Zhang, Z, Xu, R.M, Zhu, B. | | 登録日 | 2021-08-25 | | 公開日 | 2022-02-16 | | 最終更新日 | 2022-03-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Highly enriched BEND3 prevents the premature activation of bivalent genes during differentiation.
Science, 375, 2022
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7VWK
 | | The product template domain of AviM | | 分子名称: | Polyketide synthase | | 著者 | Feng, Y, Yang, X, Zheng, J. | | 登録日 | 2021-11-10 | | 公開日 | 2022-06-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Streptomyces viridochromogenes product template domain represents an evolutionary intermediate between dehydratase and aldol cyclase of type I polyketide synthases.
Commun Biol, 5, 2022
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7BVV
 | | Crystal structure of sulfonic peroxiredoxin Ahp1 in complex with thioredoxin Trx2 | | 分子名称: | Peroxiredoxin AHP1, Thioredoxin-2 | | 著者 | Lian, F.M, Jiang, Y.L, Yang, W, Yang, X. | | 登録日 | 2020-04-11 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Crystal structure of sulfonic peroxiredoxin Ahp1 in complex with thioredoxin Trx2 mimics a conformational intermediate during the catalytic cycle.
Int.J.Biol.Macromol., 161, 2020
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7CWK
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7FEE
 | | Crystal structure of the allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole, ... | | 著者 | Wang, X, Zhao, C, Shao, Z. | | 登録日 | 2021-07-19 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1.
Nat.Chem.Biol., 18, 2022
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3GJ9
 | | crystal structure of TIP-1 in complex with c-terminal of Kir2.3 | | 分子名称: | C-terminal peptide from Inward rectifier potassium channel 4, CHLORIDE ION, Tax1-binding protein 3, ... | | 著者 | Shen, Y. | | 登録日 | 2009-03-08 | | 公開日 | 2009-12-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular mechanism of inward rectifier potassium channel 2.3 regulation by tax-interacting protein-1
J.Mol.Biol., 392, 2009
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7YW3
 | | Crystal structure of tRNA 2'-phosphotransferase from Homo sapiens | | 分子名称: | 1,2-ETHANEDIOL, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, tRNA 2'-phosphotransferase 1 | | 著者 | Yang, X.Y, Liu, X.H. | | 登録日 | 2022-08-21 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.
Nucleic Acids Res., 51, 2023
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7YW4
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7YW2
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3OQ1
 | | Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor | | 分子名称: | 3-(2-fluoroethyl)-4-({4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl}sulfonyl)benzonitrile, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, Z, Sudom, A, Walker, N.P. | | 登録日 | 2010-09-02 | | 公開日 | 2011-07-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The synthesis and SAR of novel diarylsulfone 11beta-HSD1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
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7WV9
 | | Allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 in complex with Gi protein | | 分子名称: | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, ... | | 著者 | Xu, Z, Shao, Z. | | 登録日 | 2022-02-10 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1.
Nat.Chem.Biol., 18, 2022
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7YLL
 | | Crystal structure of TTEDbh | | 分子名称: | DNA polymerase IV, MAGNESIUM ION, PHOSPHATE ION | | 著者 | Yan, X, Tian, L, Gao, H. | | 登録日 | 2022-07-26 | | 公開日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.6000092 Å) | | 主引用文献 | Structure and function of extreme TLS DNA polymerase TTEDbh from Thermoanaerobacter tengcongensis.
Int.J.Biol.Macromol., 253, 2023
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7YG4
 | | Structure of WTAP-VIRMA in the m6A writer complex | | 分子名称: | Pre-mRNA-splicing regulator WTAP, Protein virilizer homolog | | 著者 | Yan, X.H, Guan, Z.Y, Tang, C, Yin, P. | | 登録日 | 2022-07-11 | | 公開日 | 2022-11-23 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | AI-empowered integrative structural characterization of m 6 A methyltransferase complex.
Cell Res., 32, 2022
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7YFJ
 | | Crystal structure of human WTAP | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Pre-mRNA-splicing regulator WTAP | | 著者 | Yan, X.H, Guan, Z.Y, Tang, C, Yin, P. | | 登録日 | 2022-07-08 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | AI-empowered integrative structural characterization of m 6 A methyltransferase complex.
Cell Res., 32, 2022
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4I0N
 | | Pore forming protein | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Necrotic enteritis toxin B | | 著者 | Yan, X, Porter, C.J, Hardy, S.P, Steer, D, Smith, A.I, Quinset, N, Hughes, V, Cheung, J.K, Keyburn, A.L, Kaldhusdal, M, Moore, R.J, Bannam, T.L, Whisstock, J.C, Rood, J.I. | | 登録日 | 2012-11-16 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and functional analysis of the pore-forming toxin NetB from Clostridium perfringens
MBio, 4, 2013
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5Y4R
 | | Structure of a methyltransferase complex | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Chemotaxis protein methyltransferase 1, Cyclic diguanosine monophosphate-binding protein PA4608, ... | | 著者 | Yan, X, Xin, L, Tan, Y.J, Jin, S, Liang, Z.X, Gao, Y.G. | | 登録日 | 2017-08-04 | | 公開日 | 2017-11-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein.
J. Biol. Chem., 293, 2018
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5Y4S
 | | Structure of a methyltransferase complex | | 分子名称: | Chemotaxis protein methyltransferase 1 | | 著者 | Yan, X, Xin, L, Tan, Y.J, Jin, S, Liang, Z.X, Gao, Y.G. | | 登録日 | 2017-08-04 | | 公開日 | 2017-11-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.405 Å) | | 主引用文献 | Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein.
J. Biol. Chem., 293, 2018
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4QNC
 | | Crystal structure of a SemiSWEET in an occluded state | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PENTADECANE, chemical transport protein | | 著者 | Yan, X, Yuyong, T, Liang, F, Perry, K. | | 登録日 | 2014-06-17 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.388 Å) | | 主引用文献 | Structures of bacterial homologues of SWEET transporters in two distinct conformations.
Nature, 515, 2014
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4QND
 | | Crystal structure of a SemiSWEET | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Chemical transport protein, ... | | 著者 | Yan, X, Yuyong, T, Liang, F, Perry, K. | | 登録日 | 2014-06-17 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Structures of bacterial homologues of SWEET transporters in two distinct conformations.
Nature, 515, 2014
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