7WKO
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![BU of 7wko by Molmil](/molmil-images/mine/7wko) | ICP1 Csy1-2 complex | 分子名称: | Csy1, Csy2 | 著者 | Zhang, M, Peng, R. | 登録日 | 2022-01-10 | 公開日 | 2023-04-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage. Proc.Natl.Acad.Sci.USA, 120, 2023
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5J09
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4MXL
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![BU of 4mxl by Molmil](/molmil-images/mine/4mxl) | X-ray structure of ZnPFeBMb1 | 分子名称: | Myoglobin, PROTOPORPHYRIN IX CONTAINING ZN | 著者 | Chakraborty, S, Lu, Y, Petrik, I. | 登録日 | 2013-09-26 | 公開日 | 2014-02-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Spectroscopic and computational study of a nonheme iron nitrosyl center in a biosynthetic model of nitric oxide reductase. Angew.Chem.Int.Ed.Engl., 53, 2014
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4N6F
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![BU of 4n6f by Molmil](/molmil-images/mine/4n6f) | Crystal structure of Amycolatopsis orientalis BexX complexed with G6P | 分子名称: | CALCIUM ION, FRUCTOSE -6-PHOSPHATE, Putative thiosugar synthase | 著者 | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | 登録日 | 2013-10-11 | 公開日 | 2014-05-14 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis. Nature, 509, 2014
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7EQ4
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![BU of 7eq4 by Molmil](/molmil-images/mine/7eq4) | Crystal Structure of the N-terminus of Nonstructural protein 1 from SARS-CoV-2 | 分子名称: | Host translation inhibitor nsp1 | 著者 | Liu, Y, Ke, Z, Hu, H, Zhao, K, Xiao, J, Xia, Y, Li, Y. | 登録日 | 2021-04-29 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1. Microbiol Spectr, 9, 2021
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7BTD
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7BTA
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7BTC
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1G69
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![BU of 1g69 by Molmil](/molmil-images/mine/1g69) | THIAMIN PHOSPHATE SYNTHASE | 分子名称: | 2-METHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, 4-METHYL-5-HYDROXYETHYLTHIAZOLE PHOSPHATE, MAGNESIUM ION, ... | 著者 | Peapus, D.H, Chiu, H.-J, Campobasso, N, Reddick, J.J, Begley, T.P, Ealick, S.E. | 登録日 | 2000-11-03 | 公開日 | 2001-09-26 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase. Biochemistry, 40, 2001
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7FIF
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![BU of 7fif by Molmil](/molmil-images/mine/7fif) | Cryo-EM structure of the hedgehog release protein Disp from water bear (Hypsibius dujardini) | 分子名称: | Protein dispatched-like protein 1 | 著者 | Luo, Y, Wan, G, Wang, Q, Zhao, Y, Cong, Y, Li, D. | 登録日 | 2021-07-31 | 公開日 | 2021-09-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Architecture of Dispatched, a Transmembrane Protein Responsible for Hedgehog Release. Front Mol Biosci, 8, 2021
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6BZ3
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![BU of 6bz3 by Molmil](/molmil-images/mine/6bz3) | Complex structure of FAK FAT domain and DCC P3 motif | 分子名称: | CALCIUM ION, Focal adhesion kinase 1, Netrin receptor DCC | 著者 | Xu, S, Wang, J.-H. | 登録日 | 2017-12-22 | 公開日 | 2018-04-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.497 Å) | 主引用文献 | The binding of DCC-P3 motif and FAK-FAT domain mediates the initial step of netrin-1/DCC signaling for axon attraction. Cell Discov, 4, 2018
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7EVR
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![BU of 7evr by Molmil](/molmil-images/mine/7evr) | Crystal structure of hnRNP L RRM2 in complex with SETD2 | 分子名称: | Heterogeneous nuclear ribonucleoprotein L, SHI domain from Histone-lysine N-methyltransferase SETD2 | 著者 | Li, F.D, Wang, S.M. | 登録日 | 2021-05-22 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing. Nat Commun, 12, 2021
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7EVS
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![BU of 7evs by Molmil](/molmil-images/mine/7evs) | Crystal structure of hnRNP LL RRM2 in complex with SETD2 | 分子名称: | Heterogeneous nuclear ribonucleoprotein L-like, SHI domain from Histone-lysine N-methyltransferase SETD2, SULFATE ION | 著者 | Li, F.D, Wang, S.M. | 登録日 | 2021-05-22 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing. Nat Commun, 12, 2021
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7F58
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![BU of 7f58 by Molmil](/molmil-images/mine/7f58) | Cryo-EM structure of THIQ-MC4R-Gs_Nb35 complex | 分子名称: | (3R)-N-[(2R)-3-(4-chlorophenyl)-1-[4-cyclohexyl-4-(1,2,4-triazol-1-ylmethyl)piperidin-1-yl]-1-oxidanylidene-propan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhang, H, Chen, L, Mao, C, Shen, Q, Yang, D, Shen, D, Qin, J. | 登録日 | 2021-06-21 | 公開日 | 2021-11-03 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Res., 31, 2021
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7F54
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![BU of 7f54 by Molmil](/molmil-images/mine/7f54) | Cryo-EM structure of afamelanotide-MC4R-Gs_Nb35 complex | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, H, Chen, L, Mao, C, Shen, Q, Yang, D, Shen, D, Qin, J. | 登録日 | 2021-06-21 | 公開日 | 2021-11-03 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Res., 31, 2021
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7F55
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![BU of 7f55 by Molmil](/molmil-images/mine/7f55) | Cryo-EM structure of bremelanotide-MC4R-Gs_Nb35 complex | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, H, Chen, L, Mao, C, Shen, Q, Yang, D, Shen, D, Qin, J. | 登録日 | 2021-06-21 | 公開日 | 2021-11-03 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Res., 31, 2021
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7DAJ
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![BU of 7daj by Molmil](/molmil-images/mine/7daj) | The crystal structure of serotonin N-acetyltransferase in complex with acetyl-CoA from Oryza Sativa | 分子名称: | ACETYL COENZYME *A, Serotonin N-acetyltransferase 1, chloroplastic | 著者 | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | 登録日 | 2020-10-16 | 公開日 | 2021-09-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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1G6C
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![BU of 1g6c by Molmil](/molmil-images/mine/1g6c) | THIAMIN PHOSPHATE SYNTHASE | 分子名称: | 2-TRIFLUOROMETHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, 4-METHYL-5-HYDROXYETHYLTHIAZOLE PHOSPHATE, MAGNESIUM ION, ... | 著者 | Peapus, D.H, Chiu, H.-J, Campobasso, N, Reddick, J.J, Begley, T.P, Ealick, S.E. | 登録日 | 2000-11-03 | 公開日 | 2001-09-26 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase. Biochemistry, 40, 2001
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7DAL
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![BU of 7dal by Molmil](/molmil-images/mine/7dal) | The crystal structure of a serotonin N-acetyltransferase in complex with serotonin and acetyl-CoA from Oryza Sativa | 分子名称: | ACETYL COENZYME *A, SEROTONIN, Serotonin N-acetyltransferase 1, ... | 著者 | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | 登録日 | 2020-10-16 | 公開日 | 2021-09-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DAI
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![BU of 7dai by Molmil](/molmil-images/mine/7dai) | The crystal structure of a serotonin N-acetyltransferase from Oryza Sativa | 分子名称: | Serotonin N-acetyltransferase 1, chloroplastic | 著者 | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | 登録日 | 2020-10-16 | 公開日 | 2021-09-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DAK
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![BU of 7dak by Molmil](/molmil-images/mine/7dak) | The crystal structure of a serotonin N-acetyltransferase in complex with 5-Methoxytryptamine and acetyl-CoA from Oryza Sativa | 分子名称: | 2-(5-methoxy-1H-indol-3-yl)ethanamine, ACETYL COENZYME *A, Serotonin N-acetyltransferase 1, ... | 著者 | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | 登録日 | 2020-10-16 | 公開日 | 2021-09-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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1G4E
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![BU of 1g4e by Molmil](/molmil-images/mine/1g4e) | THIAMIN PHOSPHATE SYNTHASE | 分子名称: | THIAMIN PHOSPHATE SYNTHASE | 著者 | Peapus, D.H, Chiu, H.-J, Campobasso, N, Reddick, J.J, Begley, T.P, Ealick, S.E. | 登録日 | 2000-10-26 | 公開日 | 2001-09-26 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase. Biochemistry, 40, 2001
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1G4T
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![BU of 1g4t by Molmil](/molmil-images/mine/1g4t) | THIAMIN PHOSPHATE SYNTHASE | 分子名称: | 3-(4-AMINO-2-TRIFLUOROMETHYL-PYRIMIDIN-5-YLMETHYL)-4-METHYL-5-(2-PHOSPHONATOOXY-ETHYL)-THIAZOL-3-IUM, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | 著者 | Peapus, D.H, Chiu, H.-J, Campobasso, N, Reddick, J.J, Begley, T.P, Ealick, S.E. | 登録日 | 2000-10-28 | 公開日 | 2001-09-26 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase. Biochemistry, 40, 2001
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7F53
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![BU of 7f53 by Molmil](/molmil-images/mine/7f53) | Cryo-EM structure of a-MSH-MC4R-Gs_Nb35 complex | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, H, Chen, L, Mao, C, Shen, Q, Yang, D, Shen, D, Qin, J. | 登録日 | 2021-06-21 | 公開日 | 2021-11-03 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Res., 31, 2021
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7FAJ
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![BU of 7faj by Molmil](/molmil-images/mine/7faj) | CARM1 bound with compound 43 | 分子名称: | Histone-arginine methyltransferase CARM1, N'-[[3-[4-(3,5-dimethyl-1,2-oxazol-4-yl)-5-methyl-6-phenylazanyl-pyrimidin-2-yl]phenyl]methyl]-N-methyl-ethane-1,2-diamine | 著者 | Cao, D.Y, Li, J, Xiong, B. | 登録日 | 2021-07-06 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2450726 Å) | 主引用文献 | Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy. J.Med.Chem., 64, 2021
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