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7F55

Cryo-EM structure of bremelanotide-MC4R-Gs_Nb35 complex

Summary for 7F55
Entry DOI10.2210/pdb7f55/pdb
EMDB information31456 31457 31458 31461
DescriptorIsoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
Functional Keywordssingle particle, membrane protein, class a g-protein-coupled receptors
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains6
Total formula weight164683.48
Authors
Zhang, H.,Chen, L.,Mao, C.,Shen, Q.,Yang, D.,Shen, D.,Qin, J. (deposition date: 2021-06-21, release date: 2021-11-03, Last modification date: 2022-02-16)
Primary citationZhang, H.,Chen, L.N.,Yang, D.,Mao, C.,Shen, Q.,Feng, W.,Shen, D.D.,Dai, A.,Xie, S.,Zhou, Y.,Qin, J.,Sun, J.P.,Scharf, D.H.,Hou, T.,Zhou, T.,Wang, M.W.,Zhang, Y.
Structural insights into ligand recognition and activation of the melanocortin-4 receptor.
Cell Res., 31:1163-1175, 2021
Cited by
PubMed: 34433901
DOI: 10.1038/s41422-021-00552-3
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation

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