3LIK
 
 | | Human MMP12 in complex with non-zinc chelating inhibitor | | 分子名称: | ACETOHYDROXAMIC ACID, CALCIUM ION, HEXAETHYLENE GLYCOL, ... | | 著者 | Stura, E.A, Dive, V, Devel, L, Czarny, B, Vera, L, Beau, F. | | 登録日 | 2010-01-25 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
J.Biol.Chem., 285, 2010
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3LJX
 | | Crystal Structure of MmoQ Response regulator (fragment 20-298) from Methylococcus capsulatus str. Bath, Northeast Structural Genomics Consortium Target McR175G | | 分子名称: | CHLORIDE ION, MmoQ Response regulator | | 著者 | Kuzin, A, Scott, L, Forouhar, F, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-01-26 | | 公開日 | 2010-02-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Northeast Structural Genomics Consortium Target McR175G
To be published, 2009
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3CWX
 | | Crystal structure of cagd from helicobacter pylori pathogenicity island | | 分子名称: | protein CagD | | 著者 | Cendron, L, Zanotti, G, Angelini, A, Barison, N, Couturier, M, Stein, M. | | 登録日 | 2008-04-23 | | 公開日 | 2008-12-30 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion.
J.Mol.Biol., 386, 2009
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3LM6
 | | Crystal Structure of Stage V sporulation protein AD (spoVAD) from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR525 | | 分子名称: | Stage V sporulation protein AD | | 著者 | Forouhar, F, Su, M, Seetharaman, J, Fang, F, Xiao, R, Cunningham, K, Ma, L, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-01-29 | | 公開日 | 2010-02-16 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Northeast Structural Genomics Consortium Target SR525
To be Published
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5ZUF
 | | Fit R10 Fab coordinates into the cryo-EM of EV71 in complex with A9 | | 分子名称: | Capsid protein VP1, R10 ANTIBODY HEAVY CHAIN, R10 ANTIBODY LIGHT CHAIN, ... | | 著者 | Wang, X, Zhu, L, Wang, N. | | 登録日 | 2018-05-07 | | 公開日 | 2019-12-25 | | 最終更新日 | 2021-01-06 | | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | | 主引用文献 | Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71.
Mbio, 9, 2018
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6ADS
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4FYG
 | | Structural basis for substrate recognition by a novel Legionella phosphoinositide phosphatase | | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, SidF, inhibitor of growth family, ... | | 著者 | Hsu, F.S, Zhu, W, Brennan, L, Tao, L, Luo, Z.Q, Mao, Y. | | 登録日 | 2012-07-04 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.822 Å) | | 主引用文献 | Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3HDL
 | | Crystal Structure of Highly Glycosylated Peroxidase from Royal Palm Tree | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Watanabe, L, Moura, P.R, Bleicher, L, Nascimento, A.S, Zamorano, L.S, Calvete, J.J, Bursakov, S, Roig, M.G, Shnyrov, V.L, Polikarpov, I. | | 登録日 | 2009-05-07 | | 公開日 | 2009-11-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia).
J.Struct.Biol., 169, 2010
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2AAA
 | | CALCIUM BINDING IN ALPHA-AMYLASES: AN X-RAY DIFFRACTION STUDY AT 2.1 ANGSTROMS RESOLUTION OF TWO ENZYMES FROM ASPERGILLUS | | 分子名称: | ALPHA-AMYLASE, CALCIUM ION | | 著者 | Brady, L, Brzozowski, A.M, Derewenda, Z, Dodson, E.J, Dodson, G.G. | | 登録日 | 1991-02-27 | | 公開日 | 1993-07-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Calcium binding in alpha-amylases: an X-ray diffraction study at 2.1-A resolution of two enzymes from Aspergillus.
Biochemistry, 29, 1990
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4CXL
 | | Human insulin analogue (D-ProB8)-insulin | | 分子名称: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN | | 著者 | Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L. | | 登録日 | 2014-04-07 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53, 2014
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1N7U
 | | THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM I | | 分子名称: | ACETATE ION, Adsorption protein P2, CALCIUM ION | | 著者 | Xu, L, Benson, S.D, Butcher, S.J, Bamford, D.H, Burnett, R.M. | | 登録日 | 2002-11-18 | | 公開日 | 2003-04-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Receptor Binding Protein P2 of PRD1, a
Virus Targeting Antibiotic-Resistant Bacteria,
Has a Novel Fold Suggesting Multiple Functions.
Structure, 11, 2003
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6ADT
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1HY9
 | | COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT | | 分子名称: | COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN | | 著者 | Ludvigsen, S, Thim, L, Blom, A.M, Wulff, B.S. | | 登録日 | 2001-01-18 | | 公開日 | 2001-08-29 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold.
Biochemistry, 40, 2001
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6I9J
 | | Human transforming growth factor beta2 in a tetragonal crystal form | | 分子名称: | Transforming growth factor beta-2 proprotein | | 著者 | Gomis-Ruth, F.X, Marino-Puertas, L, del Amo-Maestro, L, Goulas, T. | | 登録日 | 2018-11-23 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor beta 2 in a new conformation.
Sci Rep, 9, 2019
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8A59
 | | C-type lectin-like domain (CTLD) and Sushi-like domain of human CD93 | | 分子名称: | Complement component C1q receptor, GLYCEROL, SULFATE ION | | 著者 | Tassone, G, Barbera, S, Raucci, L, Orlandini, M, Pozzi, C. | | 登録日 | 2022-06-14 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells.
Int.J.Biol.Macromol., 224, 2023
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1I0E
 | | CRYSTAL STRUCTURE OF CREATINE KINASE FROM HUMAN MUSCLE | | 分子名称: | CREATINE KINASE,M CHAIN | | 著者 | Shen, Y.-Q, Tang, L, Zhou, H.-M, Lin, Z.-J. | | 登録日 | 2001-01-29 | | 公開日 | 2003-04-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structure of human muscle creatine kinase.
Acta Crystallogr.,Sect.D, 57, 2001
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1N8E
 | | Fragment Double-D from Human Fibrin | | 分子名称: | Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain | | 著者 | Yang, Z, Pandi, L, Doolittle, R.F. | | 登録日 | 2002-11-20 | | 公開日 | 2003-01-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | The Crystal Structure of Fragment Double-D from Cross-Linked Lamprey Fibrin Reveals Isopeptide Linkages across an Unexpected D-D Interface
Biochemistry, 41, 2002
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4CXN
 | | Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I | | 分子名称: | INSULIN A CHAIN, INSULIN B CHAIN | | 著者 | Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L. | | 登録日 | 2014-04-07 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53, 2014
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4D07
 | | DYNLL2 dynein light chain binds to an extended, unstructured linear motif of myosin 5a tail | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT (II) ION, DYNEIN LIGHT CHAIN 2, ... | | 著者 | Bodor, A, Radnai, L, Hetenyi, C, Rapali, P, Lang, A, Kover, K.E, Perczel, A, Wahlgren, W.Y, Katona, G, Nyitray, L. | | 登録日 | 2014-04-24 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Dynll2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5A Tail that Has Structural Plasticity.
Biochemistry, 53, 2014
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8A76
 | | Metallo-beta-lactamase NDM-1 in complex with 1,2,4-Triazole-3-thione compound 26 | | 分子名称: | (2~{S})-2-[bis(pyridin-2-ylmethyl)amino]-5-(3-phenyl-5-sulfanylidene-1~{H}-1,2,4-triazol-4-yl)pentanoic acid, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Vascon, F, Legru, A, Hernandez, J.F, Cendron, L. | | 登録日 | 2022-06-20 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-beta-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.
J.Med.Chem., 65, 2022
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3ENL
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3EOP
 | | Crystal Structure of the DUF55 domain of human thymocyte nuclear protein 1 | | 分子名称: | SULFATE ION, Thymocyte nuclear protein 1 | | 著者 | Yu, F, Song, A, Xu, C, Sun, L, Li, L, Tang, L, Hu, H, He, J. | | 登録日 | 2008-09-29 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Determining the DUF55-domain structure of human thymocyte nuclear protein 1 from crystals partially twinned by tetartohedry
Acta Crystallogr.,Sect.D, 65, 2009
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7ZL9
 | | Crystal structure of human GPCR Niacin receptor (HCA2) | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, ... | | 著者 | Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, Han, G.W, FiBerto, J.F, Wu, L.J, Tong, J.H, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J. | | 登録日 | 2022-04-14 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural insights into the human niacin receptor HCA2-G i signalling complex.
Nat Commun, 14, 2023
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7ZLY
 | | Crystal structure of human GPCR Niacin receptor (HCA2) expressed from Spodoptera frugiperda | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, OLEIC ACID | | 著者 | Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, FiBerto, J.F, Wu, L.J, Tong, J.H, Han, G.W, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J. | | 登録日 | 2022-04-17 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural insights into the human niacin receptor HCA2-G i signalling complex.
Nat Commun, 14, 2023
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6APL
 | | Crystal Structure of human ST6GALNAC2 in complex with CMP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, CYTIDINE-5'-MONOPHOSPHATE | | 著者 | Forouhar, F, Moremen, K.W, Northeast Structural Genomics Consortium (NESG), Tong, L. | | 登録日 | 2017-08-17 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Expression system for structural and functional studies of human glycosylation enzymes.
Nat. Chem. Biol., 14, 2018
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