6APL
Crystal Structure of human ST6GALNAC2 in complex with CMP
Summary for 6APL
Entry DOI | 10.2210/pdb6apl/pdb |
Descriptor | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, CYTIDINE-5'-MONOPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | glycosyltransferase, transferase, structural genomics, psi-biology, northeast structural genomics consortium, nesg |
Biological source | Homo sapiens (Human) |
Cellular location | Golgi apparatus membrane ; Single-pass type II membrane protein : Q9UJ37 |
Total number of polymer chains | 6 |
Total formula weight | 257780.12 |
Authors | Forouhar, F.,Moremen, K.W.,Northeast Structural Genomics Consortium (NESG),Tong, L. (deposition date: 2017-08-17, release date: 2017-12-20, Last modification date: 2024-04-03) |
Primary citation | Moremen, K.W.,Ramiah, A.,Stuart, M.,Steel, J.,Meng, L.,Forouhar, F.,Moniz, H.A.,Gahlay, G.,Gao, Z.,Chapla, D.,Wang, S.,Yang, J.Y.,Prabhakar, P.K.,Johnson, R.,Rosa, M.D.,Geisler, C.,Nairn, A.V.,Seetharaman, J.,Wu, S.C.,Tong, L.,Gilbert, H.J.,LaBaer, J.,Jarvis, D.L. Expression system for structural and functional studies of human glycosylation enzymes. Nat. Chem. Biol., 14:156-162, 2018 Cited by PubMed: 29251719DOI: 10.1038/nchembio.2539 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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